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Öğe Clinical Presentation of Primary Thyroid Tuberculosis(Mary Ann Liebert Inc, 2010) Akbulut, Sami; Gomceli, Ismail; Cakabay, Bahri; Arikok, Ata Turker; Sezgin, Arsenal; Bakir, Sule[Abstract Not Available]Öğe Ga-68-FAPI-04 PET/CT, a new step in breast cancer imaging: a comparative pilot study with the F-18-FDG PET/CT(Springer, 2021) Kömek, Halil; Can, Canan; Güzel, Yunus; Oruç, Zeynep; Gündoğan, Cihan; Yıldırım, Özgen Ahmet; Kaplan, İhsan; Erdur, Erkan; Yıldırım, Mehmet Serdar; Cakabay, BahriAbstract Aim We aimed to compare the roles of Ga-68-FAPI-04 PET/CT and F-18-FDG PET/CT in the evaluation of primary tumor and metastases in primary and recurrent breast cancer. Materials and method Twenty female patients with histopathologically confirmed primary and recurrent breast cancer were included in the prospective study. All patients underwent FDG and FAPI PET/CT imaging in the same week. The number of primary and metastatic lesions, SUVmax values, and tumor-to-background ratios (TBR) were recorded from both scans. Data obtained were statistically compared. Results FAPI PET/CT was superior to FDG in detecting breast lesions, as well as hepatic, bone, lymph node, and cerebral metastases in terms of patient- and lesion-based assessments. The sensitivity and specificity of FAPI in detecting primary breast lesions were 100% and 95.6%, respectively, while the sensitivity and specificity of FDG were 78.2% and 100%, respectively. The SUVmax values of primary breast tumors, lymph nodes, lung metastases, and bone metastases were significantly higher on FAPI imaging than FDG imaging (p < 0.05). However, SUVmax values of hepatic metastases did not exhibit a statistically significant difference between two imaging techniques (p > 0.05). Also, FAPI imaging yielded significantly higher TBR in breast lesions as well as hepatic, bone, brain and lung metastases compared to FDG (p < 0.05). Conclusion (68) Ga-FAPI-04 PET/CT is superior to F-18-FDG PET/CT in detecting the primary tumor in patients with breast cancer with its high sensitivity, high SUVmax, and high TBR. (68) Ga-FAPI-04 PET/CT is also superior to F-18-FDG PET/CT in detecting lymph node, hepatic, bone, and cerebral metastases because it has lower background activity and higher uptake in subcentimetric lesions.Öğe Giant vesical diverticulum: A rare cause of defecation disturbance(Baishideng Publishing Group Inc, 2009) Akbulut, Sami; Cakabay, Bahri; Sezgin, Arsenal; Isen, Kenan; Senol, AyhanVesical diverticula frequently result from bladder outlet obstructions. However, giant vesical diverticula which cause acute abdomen or intestinal obstruction are very rare. Our review of the English medical literature found 3 cases of bladder diverticula which caused gastrointestinal symptoms. Here, we present a 57-year-old man with a giant diverticulum of the urinary bladder who complained of abdominal pain, nausea and vomiting, constipation, no passage of gas or feces, and abdominal distension for 3 d. A 20 cm x 15 cm diverticulum was observed upon laparotomy. The colonic obstruction was secondary to external compression of the rectum against the sacrum by a distended vesical diverticulum. We performed a diverticulectomy and primary closure. Twelve months postoperatively, the patient had no difficulty with voiding or defecation. (c) 2009 The WJG Press and Baishideng. All rights reserved.Öğe Patent vitelline duct as a cause of acute abdomen: Case report of an adult patient(Turkish Soc Gastroenterology, 2011) Alevli, Feride; Akbulut, Sami; Dolek, Yasemin; Cakabay, Bahri; Sezgin, ArsenalA patent vitelline duct is an uncommon condition. Diagnosis is based on clinical and radiological findings. Complications include prolapse, intestinal obstruction, hemorrhage, and perforation. Here, we report the case of a 23-year-old man with patent vitelline duct who presented with umbilical discharge, severe abdominal pain, fever of 38.5 degrees C, no gas/feces passage, and nausea and vomiting for three days. Laparotomy with midline incision was performed because of acute abdomen. A patent vitelline duct from the terminal ileum to the umbilicus was observed. Meckel's diverticulitis and ileus were also noted. En bloc resection of the umbilicus, patent uitelline duct and a 15 cm ileal segment was performed. The patient was discharged five days after the operation.Öğe Radical vs conservative surgery for hydatid liver cysts: Experience from single center(Baishideng Publishing Group Inc, 2010) Akbulut, Sami; Senol, Ayhan; Sezgin, Arsenal; Cakabay, Bahri; Dursun, Mehmet; Satici, OmerAIM: To compare the efficacy and safety of radical and conservative surgical interventions for liver hydatid disease. METHODS: The study comprised 59 patients in two groups who had undergone radical and conservative surgical procedures for liver hydatid disease in our department between 2004 and 2009. Preoperative diagnostic tools, medical treatments, demographic and clinical characteristics, postoperative follow-up, and recurrence were compared in both groups. RESULTS: This non-randomized retrospective study included 59 patients who had undergone liver hydatid disease surgery. The radical technique was used in 18 patients (mean age: 42.1 +/- 13.5 years, seven male, 11 female), and the conservative technique was used in 41 patients (mean age: 43.5 +/- 13.9 years, 17 male, 24 female). The follow-up period ranged from 3 to 58 mo. Although operative time was significantly shorter in the conservative group (P < 0.001), recurrence was significantly reduced in the radical group (P = 0.045). No statistically significant differences were found in terms of hospitalization duration, cyst count and size, location, postoperative complications, scolicidal solution usage, or follow-up duration between the two groups. CONCLUSION: The more effective method for preventing postoperative recurrence is radical surgery. Endoscopic retrograde cholangiopancreatography for bile leakage in the early postoperative period may decrease the requirement for repeat surgery. (C) 2010 Baishideng. All rights reserved.Öğe A rare cause of severe dyspareunia: a case report and literature review(Springer Heidelberg, 2010) Akbulut, Sami; Cakabay, Bahri; Sezgin, Arsenal; Ozmen, CihanGastrointestinal stromal tumors (GISTs) of the rectum are rare, and their clinical manifestations are variable. We report the case of a 23-year-old woman who was referred complaining of dyspareunia during coitus. We performed digital vaginal and rectal investigations, ultrasound, colonoscopy, and computed tomography. These examinations confirmed the presence of a lesion measuring about 6 x 5 x 5 cm in size attached to the posterolateral left rectum wall. We performed a circumanal excision, then arrived at the mass between the muscles of the pelvic floor. Pathological studies indicated that the tumor was a high-grade GIST, and was clear at the surgical margins. On follow-up, a GIST was found at the gastric fundus via an endoscopic biopsy. Imatinib treatment was initiated because the patient refused a second operation. The gastric lesion disappeared 6 months after imatinib treatment. Dyspareunia disappeared 1 month after operation.Öğe Retroperitoneal Fibrosis and Hydronephrosis due to Actinomycosis(Mary Ann Liebert, Inc, 2009) Akbulut, Sami; Cakabay, Bahri; Sezgin, Arsenal; Ozmen, Cihan Akgul; Isen, Kenan; Bakir, CetinPurpose: In this article, we present a case of actinomycosis causing fibrosis and bilateral obstructive uropathy. Methods: A 43-year-old woman was admitted to the hospital with left flank pain. Abdominal computed tomography showed bilateral hydroureteronephrosis and a malignant mass. The fine-needle aspiration biopsy was reported as retroperitoneal fibrosis. Stents were placed in both ureters. Two (2) months later, laparotomy revealed a mass located just below the origin of the inferior mesenteric artery. Bilateral ureterolysis and sigmoid colon resection was performed. Results: The pathology report was fibrosis and actinomycosis. She was given parenteral crystallized penicillin 4 x 5 million units/day for 21 days, followed by oral cotrimoxazole (960 mg) for 6 months. Conclusions: Because actinomycosis was not diagnosed either radiologically or pathologically, the patient underwent immunosuppressive therapy for 2 months preoperatively.Öğe An unusual cause of ileal perforation: Report of a case and literature review(W J G Press, 2009) Akbulut, Sami; Cakabay, Bahri; Ozmen, Cihan Akgul; Sezgin, Arsenal; Sevinc, Mahsuni MertAn ileal perforation resulting from a migrated biliary stent is a rare complication of endoscopic stent placement for benign or malignant biliary tract disease. We describe the case of a 59-year-old woman with a history of abdominal surgery in which a migrated biliary stent resulted in an ileal perforation. Patients with comorbid abdominal pathologies, including colonic diverticuli, parastomal hernia, or abdominal hernia, may be at increased risk of perforation from migrated stems. (C) 2009 The WJG Press and Baishideng. All rights reserved
