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    Anterior hepatic grooves accompanied by Chilaiditi sign: a retrospective radiological analysis of a neglected anatomical fact
    (Springer France, 2015) Yavuz, Alpaslan; Batur, Abdussamet; Bulut, Mehmet Deniz; Bora, Aydin; Goya, Cemil; Andic, Cagatay; Beyazal, Mehmet
    To evaluate anterior hepatic grooves (AHGs) associated with hepato-diaphragmatic mesocolic indentations (Chilaiditi sign) and to delineate the incidence and potential clinical significance of this association. Between November 2011 and June 2014, abdominal computed tomography examinations of 2,314 patients with varied indications were retrospectively reviewed. Patients were surveyed consecutively for the Chilaiditi sign and syndrome, and cases with grooves at the antero-inferior hepatic surface enclosing the adjacent mesocolic indents were determined. The incidence of AHGs and their predominance by gender and age were determined. The potential clinical significance of AHGs associated with Chilaiditi syndrome and their possible effect on liver volume were assessed. The incidences of AHGs were similar between genders (p = .461 and p = .646) and age (p = .113 and .621, respectively) among total cohort and patients with Chilaiditi sign, respectively. There was no significant correlation between AHGs and Chilaiditi syndrome (p = .506); no efficacies of AHGs to liver volume were assessed (p = .413). The AHGs are rare adaptive changes in shape of the liver without a significant effect on liver volume. This overlooked phenomenon is likely derived from the Chilaiditi sign, but has no significant correlation with Chilaiditi syndrome. Future studies with extended series are encouraged to reveal the possible significance of this phenomenon based on concerned surgical interventions.
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    Decreased Vertebral Artery Hemodynamics in Patients with Loss of Cervical Lordosis
    (Int Scientific Information, Inc, 2016) Bulut, Mehmet Deniz; Alpayci, Mahmut; Senkoy, Emre; Bora, Aydin; Yazmalar, Levent; Yavuz, Alpaslan; Gulsen, Ismail
    Background: Because loss of cervical lordosis leads to disrupted biomechanics, the natural lordotic curvature is considered to be an ideal posture for the cervical spine. The vertebral arteries proceed in the transverse foramen of each cervical vertebra. Considering that the vertebral arteries travel in close anatomical relationship to the cervical spine, we speculated that the loss of cervical lordosis may affect vertebral artery hemodynamics. The aim of this study was to compare the vertebral artery values between subjects with and without loss of cervical lordosis. Material/Methods: Thirty patients with loss of cervical lordosis and 30 controls matched for age, sex, and body mass index were included in the study. Sixty vertebral arteries in patients with loss of cervical lordosis and 60 in controls without loss of cervical lordosis were evaluated by Doppler ultrasonography. Vertebral artery hemodynamics, including lumen diameter, flow volume, peak systolic velocity, end-diastolic velocity, and resistive index, were measured, and determined values were statistically compared between the patient and the control groups. Results: The means of diameter (p=0.003), flow volume (p=0.002), and peak systolic velocity (p=0.014) in patients were significantly lower as compared to controls. However, there was no significant difference between the 2 groups in terms of the end-diastolic velocity (p=0.276) and resistive index (p=0.536) parameters. Conclusions: The present study revealed a significant association between loss of cervical lordosis and decreased vertebral artery hemodynamics, including diameter, flow volume, and peak systolic velocity. Further studies are required to confirm these findings and to investigate their possible clinical implications.
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    Dyke-Davidoff-Masson sendromu iki olgu sunumu
    (Dicle Üniversitesi Tıp Fakültesi, 2014) Bulut, Mehmet Deniz; Gülşen, İsmail; Bora, Aydın; Yavuz, Alpaslan; Göya, Cemil; Batur, Abdussamet
    Dyke-Davidoff Masson sendromu nadir bir konjenital malformasyon olarak ilk kez 1933 yılında Dyke tarafından bildirilmiştir. Ana klinik bulguları; tek taraflı serebral atrofi, fasiyal asimetri, kontralateral hemiparezi ve epilepsidir. Klinik bulgular beyin hasarının büyüklüğüne bağlı olarak değişiklikler gösterebilir. Etyolojisinde prenatal enfeksiyonlar, konjenital patolojiler, doğum travması, beyin tümörleri, febril nöbetler ve beyin damar hastalıkları sorumlu tutulmuştur. Radyolojik olarak serebral atrofi ve aynı taraf lateral ventrikülde genişleme, kalvariumda kalınlaşma, mastoid hava hücreleri ve paranazal sinüslerde havalanma artışı ve bombeleşmiş temporal kemik en önemli bulgulardır. Etyolojisi ve serebral parankim hasarının büyüklüğünü saptamada başlıca magnetik rezonans görüntüleme ve bilgisayarlı tomografi yöntemleri kullanmanın yanında diffüzyon magnetik rezonans görüntülemede tanıya katkı sunabilir. Bu makalede Dyke-Davidoff Masson sendromlu iki olgu klinik bulgular ve radyolojik görüntüler eşliğinde sunulmuştur.
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    Recurrent Gliosarcoma in Pregnancy
    (Hindawi Ltd, 2014) Gulsen, Ismail; Ak, Hakan; Yilmaz, Tevfik; Bulut, Mehmet Deniz; Alkis, Ismet; Bayram, Irfan
    Gliosarcoma is a rare tumor of the central nervous system and it constitutes about 1 to 8% of all malignant gliomas. In this report we are presenting a recurrent gliosarcoma case during a pregnancy in a 30-year-old woman. This is the first report presenting gliosarcoma in the pregnancy.
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    The relationship between facet joint osteoarthritis and Modic changes of the lumbar spine: a retrospective magnetic resonance imaging study
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2016) Alpayci, Mahmut; Bulut, Mehmet Deniz; Yazmalar, Levent; Yavuz, Alpaslan; Toprak, Murat; Koparan, Ibrahim Halil; Gulsen, Ismail
    Objectives: This study aims to assess the facet joint osteoarthritis in patients with lumbar Modic changes and to investigate the relationship between the Modic types and severity of the facet joint degeneration. Patients and methods: A total of 120 patients (55 males, 65 females; mean age 55.18 +/- 9.47 years; range 40 to 75 years) were included in the study. The patients were divided into four equal groups of 30 patients according to Modic type (No Modic changes, type 1, type 2, type 3). All groups were matched with age, sex, and spinal level. A total of 180 lumbar facet joints of the patients with Modic changes (60 facet joints for each Modic type) and 60 lumbar facet joints of the patients without Modic changes were analyzed. The severity of the facet joint osteoarthritis was assessed. The degree of the facet degeneration was evaluated by using the Pathria grading system with magnetic resonance imaging. Results: Facet joint degeneration increased gradually, as the type of Modic change increased. Compared to the group without Modic changes, all three groups with Modic changes had more degenerative facet joints (all p <= 0.002). The severity of the facet joint degeneration was significantly higher in type 3 versus type 1 Modic changes (p=0.022). Conclusion: Our study results suggest that Modic changes, particularly type 3, are strongly associated with the facet joint osteoarthritis of the lumbar spine. Clinically, facet joint degeneration should be considered in the examination of low back pain inpatients with Modic changes.