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    Carpal tunnel decompression: two different mini-incision techniques
    (Verduci Publisher, 2012) Ucar, B. Y.; Demirtas, A.; Bulut, M.; Azboy, I.; Ucar, D.
    Aim: To compare two different mini-incision surgical techniques for carpal tunnel surgery. Materials and Methods: A total of 45 patients in Group 1 underwent carpal tunnel release through a 2-cm longitudinal incision made distal to the flexor crease, whereas the 45 patients in Group 2 underwent carpal tunnel release through a 2-cm longitudinal incision made proximal to the flexor crease. The self-administered Boston Questionnaire was used to assess the severity of patients' symptoms and their functional status, both before and after the surgical intervention and at their final follow-up. Patients were also asked, during the final follow-up, about the pain level of their scar tissue. Results: There was a significant decrease in the Boston Carpal Tunnel Questionnaire scores for the symptom severity scale and the functional status scale of patients in both groups, pre-operatively, post-operatively at one month and at final follow-up (p < 0.001 for both). The mean operative time for Group 2 was significantly shorter than for Group 1 (p < 0.001). At final follow-up, 11 patients in Group 1 stated they had scar tissue pain, compared to three patients in Group 2. The pain in scar tissue among Group 2 was significantly less than for Group 1 (p = 0.02). Conclusions: Due to shorter operative times, mini-incisions proximal to the flexor crease can be performed. The absence of relapse and good clinical results make both surgical techniques suitable. For this reason, we consider that the selection of the mini-surgical technique used should depend on the experience and skill of the surgeon.
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    Clinical and functional outcomes and treatment options for paediatric elbow dislocations: Experiences of three trauma centres
    (Elsevier Sci Ltd, 2015) Subasi, M.; Isik, M.; Bulut, M.; Cebesoy, O.; Uludag, A.; Karakurt, L.
    Although elbow dislocations are seen rarely in children, their management remains controversial. In this study, over a 7 years period, we evaluated retrospectively the clinical and functional results of paediatric elbow dislocations managed in three different trauma centres. Pure dislocations and dislocations with associated injuries were evaluated separately. In total 56 patients met the inclusion criteria. The number of patients without additional injury was 22 out of which according to the Robert's criteria, 15 children (68%) had an excellent, four (18%) a good, one (5%) a fair, and two (9%) a poor outcome. From the thirty-four patients that had associated injuries, two (6%) had an excellent, 6 (18%) a good, 10 (29%) a fair and 16 (47%) a poor result. Overall, patients with pure dislocation were found to have a better range of motion compared to patients with dislocation and associated injuries. Prolonged follow ups, and effective rehabilitation programs are required in order to expect good outcomes. (C) 2015 Elsevier Ltd. All rights reserved.
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    Comparison of long-term results of obliterative colpocleisis and reconstructive vaginal surgery including sacrospinous ligament fixation in patients with total genital prolapse
    (Wolters Kluwer Medknow Publications, 2022) Agacayak, E.; Bulut, M.; Peker, N.; Gunduz, R.; Tunc, S.; Evsen, M.; Gul, T.
    Background: Treatment of total genital prolapse in elderly patients is still controversial in terms of postoperative objective and subjective results. Aim: The present study aimed to compare the long-term objective and subjective cure rates of sacrospinous ligament fixation and Le Fort operation for treatment of total genital prolapse. Patients and Methods: Patients over the age of 60 with stage 3 or 4 pelvic organ prolapse that presented to the Obstetrics and Gynaecology Clinic of the Faculty of Medicine of *** University. The study sample consisted of 17 patients that underwent Le Fort operation and 29 patients that underwent sacrospinous ligament fixation. Data on duration of operation, intraoperative complications, duration of hospital stay, and differences between preoperative and postoperative estimated blood loss, postoperative complications, and relapse in the long term were obtained. Questionnaires exploring quality of life, incontinence, and pelvic floor disorders were applied to the patients. Results: As subjective cure rates, postoperative patient satisfaction (P = 0.001), regret rate (P = 0.038) and recommendation rate (P = 0.044), as well as postoperative questionnaire results, Pelvic Floor Impact Questionnaire and SF36 were found to be significantly better in the Le Fort group (respectively P = 0.039 and 0.042). As objective cure rates, there was no difference between the two groups in terms of postoperative cystocele, rectocele, and cystorectocele (P = 0.955) and postoperative recurrence of prolapse beyond the hymen (P: 0.893). Duration of operation and duration of hospital stay were found to be significantly shorter in the Le Fort group (respectively P = 0.032 and 0.012). Conclusion: Le Fort operation could be the intervention of choice in sexually inactive elderly patients with stage 3 or 4 pelvic organ prolapse.
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    Effect of hyperbaric oxygen therapy on healing in an experimental model of degloving injury in tails of nicotine-treated rats
    (Sage Publications Ltd, 2013) Demirtas, A.; Azboy, I.; Bulut, M.; Ucar, B. Y.; Alabalik, U.; Ilgezdi, S.
    The aim of this study was to investigate the effect of hyperbaric oxygen (HBO) therapy on healing in an experimental model of a degloving injury of the tails of nicotine-treated rats. Thirty-two male Sprague-Dawley rats were randomized to four groups (n = 8): nicotine (group 1); HBO (group 2); nicotine + HBO (group 3); and control (group 4). The mean length of the necrotic parts of the tails at the degloving injury site was significantly higher in group 1 compared with groups 2, 3, and 4, and was significantly lower in group 2 compared with groups 1, 3, and 4. The mean histopathological stage of ulcers at the degloving injury site was statistically significantly higher (more severe) in group 1 compared with groups 2, 3, and 4, and was statistically significantly lower in group 2 compared with groups 1, 3, and 4. It appears that the negative effects of nicotine on wound healing in degloving injuries are negated by the positive effects of immediate HBO therapy.
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    Investigation of the effects of Enoxaparin, Fondaparinux, and Rivaroxaban used in thromboembolism prophylaxis on fracture healing in rats
    (Verduci Publisher, 2013) Demirtas, A.; Azboy, I.; Bulut, M.; Ucar, B. Y.; Alabalik, U.; Necmioglu, N. S.
    BACKGROUND: Today, there is a small number of studies on the effects of Enoxaparin and Fondaparinux used commonly in the prevention of venous thromboembolism on healing of fracture cases. AIM: The aim of this study was to investigate clinically, radiologically and histopathologically, the effects of Enoxaparin, Fondaparinux and Ri-varoxaban used in thromboembolism prophylaxis on fracture healing in a rat model of femur fracture. MATERIALS AND METHODS: Thirty-two male Sprague Dawley rats were randomized into four groups (n=8): the control group (Group 1), the Enoxaparin group (Group 2), the Fondaparinux group (Group 3), and Rivaroxaban group (Group 4). Under general anesthesia, a standard closed fracture was created in the left femur of each rat using an osteotome. Group 1 was given saline solution (1 cc/day, sc), Group 2 Enoxaparin (100 anti Xa IU/kg/day, sc), Group 3 Fondaparinux (0.2 mg/kg/day, sc), and Group 4 Rivaroxaban (3 mg/kg/day, po) for 21 days. After all rats were sacrificed at the end of day 21, their left femurs were disarticulated at the level of the hip and knee. The bony union was radiologically, clinically, and histopathologically evaluated. RESULTS: No differences were found between the groups in terms of clinical, radiological, and histopathological findings in fracture healing (p = 0.849, p = 0.731, and p = 0.395, respectively). CONCLUSIONS: Enoxaparin, Fondaparinux and Rivaroxaban used in thromboembolism prophylaxis cause no significant changes in fracture healing with short term follow up. Thus, they can be safely used in cases of fractures.