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Öğe A comparative study of conventional and liquid-based cervical cytology(Via Medica, 2016) Budak, Mehmet Sukru; Senturk, Mehmet B.; Kaya, Cihan; Akgol, Sedat; Bademkiran, Muhammed H.; Tahaoglu, Ali Emre; Yildirim, AyhanObjectives: The aim of our study is the comparison of the results of conventional smear (CC) technique and liquid-based cytology (LBC) technique used as cervical cancer screening methods. Material and methods: The results of 47954 patients submitted to smear screening in our gynecology clinic between January 2008 and December 2014 have been studied. The smear results have been divided into two groups CC and LBC according to the technique used. Results: When considering the distribution within CC group, the results were as follows: intraepithelial cell abnormalities 2,0% (n=619), insufficient sample for analysis 2,1% (n=660), Atypical squamous cells of undetermined significance (ASC-US) 1.8% (n=554), Low grade squamous intraepithelial lesion (LGSIL) 0.1% (n=35), High grade squamous intraepithelial lesion (HGSIL) 0.1% (n=16), Atypical squamous cells - cannot exclude HGSIL (ASC-H) 0.029% (n=9), Atypical glandular cells-not other wise specified (AGC-NOS) 0.012% (n=4), squamous carcinoma 0.003% (n=1). When considering the distribution in LBC group, the results were as follows: intraepithelial cell abnormalities2.1% (n=357), insufficient sample for analysis 0.9% (n=144), ASC-US 1.8% (n=296), LGSIL 0.2% (n=38), HGSIL 0.1% (n=8), ASC-H 0.1% (n=10), AGC-NOS 0.017% (n=3), squamous carcinoma 0.011% (n=2). Conclusions: Although the rates of epithelial cell abnormalities are similar for both tests, LSIL results are more frequently observed in LBC technique. In LBC technique, the number of insufficient sample for analysis is quite low compared to CC group and thus constitutes an advantage.Öğe Evaluation and Management of Patients with Hematoma After Gynecologic and Obstetric Surgery(2021) Uzundere, Osman; Ege, Serhat; Kahveci, Bekir; Budak, Mehmet Sukru; Kahveci, Gaye; Peker, Nurullah; Sucu, MeteOBJECTIVE: Postoperative hematoma following abdominal surgery is relatively rare and mainly depends on the type of surgery. Specific treatment including surgery or interventional radiology is sometimes necessary. The aim of this study is to evaluate the cases of postoperative hematoma after gynecologic and obstetric surgery.STUDY DESIGN: This is a retrospective cohort study of 30 patients with hematoma developed after gynecologic and obstetric surgery. We included the patients who hospitalized with the diagnosis of a postoperative hematoma between June 2017 and April 2019 at Gazi Yasargil Training and ResearchHospital of Health Sciences University. Hematomas occurring after endoscopic surgery and episiotomywere not included. The diagnosed cases were divided into three groups as wound hematoma, rectussheath hematoma and intra-abdominal hematoma (intraperitoneal and retroperitoneal). All cases wereassessed by patient demographics and clinical findings, hematoma of characteristics, treatment methods and results.RESULTS: A total of 30 patients were included in the study with a mean age of 33.0±8.6 years.Incidence of hematoma account for 0.2%. The mean c-reactive protein was 37.9±47.4 mg/dL at admission and 14.6±25.8 mg/dL at discharge, respectively. The decrease was statistically significant (p <0.001). The mean hemoglobin was 10.6±2.1 g/dL at admission and 10.7±1.5 g/dL at discharge. Feverwas detected in 7 (23.3%) patients. Only 12 patients (40%) were followed up by observation and symptom management. In 10 (33.3%) patients, antibiotics were included in the treatment due to infection. Inaddition, 4 patients (13.3%) had relaparotomy, 5 patients (16.7%) underwent percutaneous radiologicaldrainage and 8 (26.7%) received blood transfusion. The mean time of resorption of the hematoma was4.6 ± 2.0 days. The evaluation of the hematoma locations revealed that 14 patients (46.7%) had woundhematoma, 7 patients (23.3%) had rectus sheath hematoma (Type I: 2 cases, type II: 3 cases, type III:2 cases), 8 patients (26.7%) had pelvic hematoma and 2 patients (6.7%) had a retroperitonealhematoma. The mean hematoma size was 68.1±15.18 mm.CONCLUSIONS: In cases of hematoma resistant to antibiotic treatment and non-resorbable hematoma,we can consider percutaneous catheter drainage as an alternative to surgical interventionÖğe An investigation of the effect of placental growth factor on intrapartum fetal compromise prediction in term-induced high risk pregnancies(Via Medica, 2018) Budak, Mehmet Sukru; Toprak, Gulten; Akgol, Sedat; Obut, Mehmet; Oglak, Cemil; Bagli, Ihsan; Kahramanoglu, IlkerObjectives: To date, there is no available test to predict the risk of intrapartum fetal compromise (IFC) during labor, either starting spontaneously or induced due to obstetrics indications. The aim of this study was to examine the effectiveness of placental growth factor (PIGF) in identifying cases that develop intrapartum fetal compromise (IFC) in term high-risk pregnancies induced for labor. Material and methods: This prospective cross-sectional study was conducted on 40 IFC+ cases and 40 IFC- cases with high-risk term pregnancy and labor induction started in the Health Sciences University Gazi Yasargil Training and Research Hospital, between January 2018 and April 2018. Comparisons were made between the groups in respect of placental growth factor (PIGF) levels, and obstetric and neonatal outcomes. Results: The PIGF level was found to be statistically significantly lower in the IFC+ cases compared to the IFC- cases. For a PIGF cutoff value of 32 pg/mL for the prediction of IFC+ cases, sensitivity was 74.4%, specificity 73.2%, NPV 75% and PPV 72.5%, with a statistically significant difference determined between the groups. The IFC+ development risk increased 7.91-fold in patients with PIGF <= 32 pg/mL. Conclusions: The PIGF levels in cases of IFC+ high risk pregnancies were found to be statistically significantly lower than those of IFC-cases. However, further, large-scale randomized controlled research is necessary to demonstrate this relationship better.Öğe Mevsimsel Sıcaklık Değişikliklerinin Gestasyonel Diabetes Mellitus Prevalansı Üzerine Etkisi(2021) Obut, Mehmet; Kahramanoğlu, Özge; Budak, Mehmet Sukru; Andan, Cengiz; Akgöl, Sedat; Kahveci, Bekir; Kahramanoğlu, İlkerAmaç: Bu çalışmada, ortam sıcaklığındaki mevsimsel değişikliklerin gestasyonel diabetes mellitus (GDM) prevalansı üzerine etkisinin araştırılmasıamaçlanmıştır.Gereç ve Yöntem: Ocak 2017-Aralık 2017 tarihleri arasında, yazları sıcak ve kurak, kışın soğuk ve yağışlı bir şehir olan Diyarbakır’da Sağlık BilimleriÜniversitesi, Gazi Yaşargil Eğitim ve Araştırma Hastanesi’nde GDM taraması yapılan 24.-28. haftalarında olan gebelerin sonuçları retrospektif olarak değerlendirildi. GDM taraması yapılan hamile kadınlar mevsimlere göre dört gruba ayrıldı. Farklı mevsimlerde GDM tanısı konulan gebelerde GDM prevalansı açısından bir karşılaştırma yapıldı.Bulgular: Taranan 3.618 gebe arasından %7,5’i (n=272) GDM tanısı aldı. GDM olgularının mevsimsel dağılımı kışın %6,4 (n=54), ilkbaharda %8,3 (n=78), yaz aylarında %9,2 (n=84) ve sonbaharda %6,1 (n=56) olmuştur. Mevsimsel dağılım açısından anlamlı bir fark gözlendi (p<0,05).Sonuç: Bu çalışmanın sonuçları, mevsimsel sıcaklık değişimlerinin GDM prevalansı üzerinde anlamlı bir etkisi olduğunu göstermiştir. Ancak, bu ilişkiyi daha iyi göstermek için daha fazla çalışmaya ihtiyaç vardırÖğe Ovarian Hyperstimulation Syndrome Continuing with Very High C Reactivity Protein Level without Infection: A Case Report and Review of the Literature(2020) Vardar, Mehmet; Kahveci, Bekir; Budak, Mehmet SukruOvarian hyperstimulation syndrome is an iatrogenic complication of supraphysiologic ovarian stimulation. The syndrome is al-most exclusively associated with exogenous gonadotropin stimulation and is only rarely observed after clomiphene citrate treatment or spon-taneous ovulation. C-reactive protein, an acute phase protein produced by the hepatocytes, is a marker of systemic inflammation, tissue damage, and/or infection. While the increased C-reactive protein level in the ovarian hyperstimulation syndrome made us think that there is an infection, for making this diagnosis, other infection indicators must be researched on these patients. Although the use of C-reactive pro-tein for infection in ovarian hyperstimulation syndrome is recommended, the level of C-reactive protein may increase without infection. We aimed to identify ovarian hyperstimulation syndrome with very high C-reactive protein level without infection.