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Öğe How to Increase the Diagnostic Value of Malignancy-related Ascites: Discriminative Ability of the Ascitic Tumour Markers(Field House Publishing Llp, 2009) Tuzun, Y.; Yilmaz, M.; Dursun, M.; Canoruc, F.; Celik, Y.; Cil, T.; Boyraz, T.Making a differential diagnosis between malignant and non-malignant ascites is an important clinical issue, but cytological examination has a relatively low diagnostic sensitivity. This study aimed to find a discriminative model that distinguished between malignancy-related and non-malignant ascites. The study included 107 patients: 50 with nonmalignant and 57 with malignant ascites. Ascites was analysed using a range of tumour markers and standard cytology. Standardized canonical discriminant function coefficients were used to distinguish between ascites types. The combination of carbohydrate antigen (CA) 15-3, carcinoembryonic antigen (CEA) and cytokeratin 19 fragments (CYFRA-21.1) discriminated between malignancy-related ascites and non-malignant ascites with an accuracy of 98.8% compared with an accuracy of 77.8% for cytological examination. In conclusion, the use of a discriminant function constructed from a combination of CA15-3, CEA and CYFRA-21.1 could distinguish malignant from non-malignant ascites with greater accuracy than cytological examination. Further studies in larger population groups are warranted.Öğe Pulmonary hypertension in essential thrombocythemia(Ferrata Storti Foundation, 2007) Altintas, A.; Boyraz, T.; Pasa, S.; Cil, T.; Kaplan, M. A.; Ayyildiz, O.[Abstract Not Available]Öğe Results of imatinib mesylate therapy in chronic myeloid leukemia: Experience of a single center(Ferrata Storti Foundation, 2007) Pasa, S.; Boyraz, T.; Beyaz, C.; Sayar, S.; Atayan, Y.[Abstract Not Available]
