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Öğe In vitro NMR proton T-1 measurements in peritoneal ascites(Iop Publishing Ltd, 1996) Yilmaz, A; Tez, M; Goral, V; Boylu, S; Kaplan, A; Kavak, GThe proton spin-lattice relaxation rate (1/T-1) in malignant and non-malignant ascites was measured with an FT NMR spectrometer operating at 60 MHz. The mean relaxation rate in non-malignant ascites was significantly smaller than that of malignant ascites. However, the 1/T-1 of malignant ascites overlaps with that of non-malignant ascites over all concentrations of total protein (TP) in samples. The 1/T-1 in non-malignant ascites correlates strongly with TP, whilst the 1/T-1 in malignant ascites shows only a moderate correlation. T-1 measurements before and after addition of ascorbic acid (reductant) suggest that there is a small paramagnetic contribution of ions to the 1/T-1 in malignant ascites. The least-squares fitting of 1/T-1 versus TP for non-malignant data gives a linear relationship, and suggests that the T-1 mechanism in non-malignant ascites is caused by a fast chemical exchange of water molecules between protein-bound water and free water.Öğe In vitro NMR proton T-1 measurements in peritoneal ascites.(W B Saunders Co-Elsevier Inc, 1997) Goral, V; Yilmaz, A; Tez, M; Boylu, S; Kaplan, A; Kavak, G[Abstract Not Available]Öğe NMR proton 1/T1 rates in bile fluid(Marcel Dekker Inc, 1996) Yilmaz, A; Boylu, S1/T1 rates in bile fluids from patients with gallstones in the gallbladder have been determined using a FT-NMR spectrometer operating at 60MHz. The inversion recovery pulse sequences (180 degrees-tau-90 degrees] were used for T1 measurements. Fluids from patients with nonobstructive. partially obstructive and complete obstructive gallstones have been studied. The mean 1/T1 in bile fluids from patients with obstructive gallstones was highly significantly different than those from patients with non-obstructive and partial obstructive gallstones. while the 1/T1 in the fluid of partially obstructive cases was significantly different than that of complete obstructive cases. This implies that in vivo MRI T1 measurements can be used for the clinical course of gallstone formation and for surgical decision about early intervention.