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Öğe CHANGES IN SERUM PARAOXONASE ACTIVITY, CALCIUM AND LIPID PROFILES IN PRE-ECLAMPSIA, A PRELIMINARY STUDY(Galenos Yayincilik, 2011) Babacan, Figen; Isik, Birgul; Bingol, BanuObjective: To investigate serum paraoxonase (PON1) activity, serum calcium, and lipid profiles in pre-eclampsia. Material and methods: Serum PON1 activity, calcium, and lipid profiles were measured in a cohort of 45 women with normal pregnancies (11 patients) and pre-eclampsia (34 patients). Results: Triglyceride, total cholesterol, and LDL cholesterol concentrations were significantly increased in women with pre-eclampsia, compared with women with normal pregnancies. Serum HDL cholesterol, PON1, and calcium levels in pre-eclamptic patients were significantly lower than those in healthy pregnant women. Conclusion: The significant decrease of PON1 activity in pre-eclampsia is related to lipid profiles and calcium.