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Öğe Acute Acalculous Cholecystitis due to Viral Hepatitis A(Hindawi Ltd, 2013) Kaya, Safak; Eskazan, Ahmet Emre; Ay, Nurettin; Baysal, Birol; Bahadir, Mehmet Veysi; Onur, Arzu; Duymus, RecaiInflammation of the gallbladder without evidence of calculi is known as acute acalculous cholecystitis (AAC). AAC is frequently associated with gangrene, perforation, and empyema. Due to these associated complications, AAC can be associated with high morbidity andmortality. Medical or surgical treatments can be chosen according to the general condition of the patient, underlying disease and agent. Particularly in acute acalculous cholecystitis cases, early diagnosis and early medical treatment have a positive effect on the patient and protect them from surgical trauma. ACC is a rare complication of acute viral hepatitis A. Herein, we present an adult patient of acalculous cholecystitis due to acute viral hepatitis A. She responded to the conservative management.Öğe Efficacy and Safety of Telbivudine in Chronic Hepatitis B Treatment Throughout the Entire Pregnancy(Galenos Yayincilik, 2016) Baysal, Birol; Kaya, Safak; Aksoz, Seluk; Comoglu, Senol; Cabalak, Mehmet; Arslan, Eyup; Colak, HabibeObjective: Women of childbearing potential treated for chronic hepatitis B virus (HBV) infection may experience exacerbations during or after pregnancy. Infants may also acquire HBV infection through perinatal route. Currently, there is no antiviral agent approved for use in pregnancy. This makes it difficult to decide whether treatment should be withdrawn immediately or continued in women who become pregnant while on HBV antiviral therapy. The present study aims to establish the safety and, as a second measure, the efficacy of telbivudine in patients who became pregnant while they were on telbivudine treatment for chronic HBV infections and were maintained on the treatment throughout pregnancy. Materials and Methods: Between 2010 and 2013, twenty-one patients, who became pregnant while receiving telbivudine treatment for chronic HBV infection and continued the treatment, were evaluated retrospectively. Results: The mean age of the patients was 28.9 +/- 6.3 years (range: 18-41 years). All patients were hepatitis B envelope antigen-negative. The mean pre-treatment hepatic activity index was 9.4 +/- 1.6 (range: 7-13), and fibrosis and serum HBV, DNA measurements were 3.2 +/- 0.8 (range: 2-5) and 3.5x10(5)+/- 2.8x10(5) IU/mL, respectively. No drug-related side effects were seen in any of the patients. All infants had normal birth weights and no abnormalities were observed in any of them. At the end of week 28, none of the infants was hepatitis B surface antigen-positive. Conclusion: The use of telbivudine from the first trimester of pregnancy appears to be safe both for the mother and fetus and to be efficient in preventing mother-to-child transmission of HBV infection. However, randomized, controlled studies involving a higher number of subjects are needed.Öğe Measuring the knowledge and attitudes of physicians towards patients with HIV/AIDS: study of Anatolian group(Emerald Group Publishing, 2021) Kaya, Şafak; Araç, Eşref; Akgül, Fethiye; Çomoğlu, Şenol; Kaya, Şehmuz; Araç, Songül; Yıldız, Yeşim; Büyüktuna, Seyit Ali; Kayaaslan, Bircan; Parlak, Emine; Baysal, Birol; Karakeçili, Faruk; Balık, Elif Zelal; Akkoç, Ali; Özdemir, Kevser; Kavak, Şeyhmus; Doğan, Suat Ali; Günay, Emrah; Karabela, Şemsi Nur; Cabalak, Mehmet; Çağ, Yasemin; Avcı, Veli; Durdu, Yasemin; Kaya, Zehra; Kılıç, Damla; Yerlikaya, Halis; Tarakçı, Hüseyin; Menteş, Osman; Tartar, Ayşe Sağmak; Köse, Adem; Alakuş, Ömer Faruk; Aktaş, Ulaş; Kömek, Halil; Aksöz, SelçukThis paper aims to determine the knowledge and attitudes of the physicians regarding human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), to emphasize that these patients exist and they will exist in the future and to raise awareness so as to prevent that their rights to treatment are revoked. Design/methodology/approach The survey was conducted via a link sent through an online system. Random physicians from 81 cities of the country were invited to the survey. The survey has 41 questions regarding knowledge and attitudes in total, including epidemiological information such as age, gender and title. Findings A total of 3,107 physicians has voluntarily participated in the study. In total, 2,195 (70.7%) are internal physicians and 912 (29.3%) are surgical physicians among the participant physicians. In total, 1,452 (46.7%) of the participants are specialist physicians, 608 (19.6%) of the participants are practising physician and the rest of it is physician assistants, academicians and dentists, respectively. Originality/value In this study, it has been found out that the physicians have a lack of knowledge on HIV/AIDS and they adopt a discriminatory attitude towards HIV-positive persons. HIV-positive patients who are exposed to discrimination and scared of being uncovered refrain from applying to hospitals for treatment, which puts public health into jeopardy due to the high viral load and these patients are faced with difficulties in coping with both medical and emotional load of the disease.Öğe Seroprevalence of Hepatitis B and C among Patients Admitted to a Tertiary Hospital(Galenos Yayincilik, 2014) Kaya, Safak; Baysal, Birol; Temiz, Hakan; Karadag, Omer; Ozdemir, Kevser; Bilman, FulyaObjectives: To evaluate seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) among patients admitted to a tertiary hospital in southeast Turkey. Materials and Methods: A retrospective study of patients admitted to the Diyarbakir Training and Research Hospital during February 2010 and July 2011. The study population consisted of patients who gave blood and tested for HBV and HCV. Data were collected from the database of our hospital. Data were analyzed using SPSS program. Results: A total of 43.131 patients tested for hepatitis B surface antigen (HBsAg) were included in this study. 4.472 patients (10.4%) were positive for HBsAg (6.8% male, 3.6% female, p<0.05). 323 (1.2%) of 28.276 patients, who underwent anti-HCV testing, were positive for anti-HCV. 381 (13.1%) of 2.899 HBsAg-positive patients were positive for hepatitis B e antigen (HBeAg). Conclusion: Although similar to that in the other regions of Turkey, the seroprevalence of hepatitis B is still high. Community awareness about the transmission and prevention of hepatitis B infection should be strengthened by health education.
