Yazar "Batun S." seçeneğine göre listele

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    Blood glucose fructosamin and HbAlc levels in cases with diabetes mellitus
    (1992) Yenice N.; Kaplan A.; Batun S.; Canoruc N.
    In this research serum glucose, fructosomin and erytroid HbAlc levels were investigated in 50 patiens with diabetes mellitus (Type I and II) and result were compared with the normal control values. (25 normal people) In the control group the levels of serum glucose, fructosamin and erytroid HmAlc were obtained as % 94.52 ± 7.7 mg; 2.29 ± 0.299 mmol/L; % 7.02 ± 0.742 respectively. In cases with Diabetes mellitus the levels of serum glycose, fructosamin and erytroid HbAlc were obtained as % 270.83 ± 98.49 mg, 4.02 ± 0.942 mmol/L, % 13.09 ± 2.387 respectively. The levels of serum glucose, fructosamine and erytroid HbAlc were increased significantly in patients with diabetes mellitus as compared with control group (p < 0.001). The serial determinations of serum fructozamin and erytroid HbAlc levels are of value in cases with diabetes mellitus in the diagnosis, treatment and in estimation of complications of diabetes mellitus which will appear in future.
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    Hereditary thrombophilic risk factors in patients with deep venous thrombosis
    (2007) Altintaş A.; Çil T.; Kaplan M.A.; Yurt M.; Batun S.
    The prevalence of hereditary risk factors for deep venous thrombosis (DVT) varies greatly in different parts of the world. Factor V Leiden (FVL) and prothrombin G 20210A (FT G20210A) are the most common genetic defects leading to venous thrombosis. The aim of this study was to investigate the frequency of FVL and PT G20210A mutations in adult patient with DVT in our region. Between September 2001 and August 2006, 52 patients with documented venous thrombosis were investigated in our center for the presence of FVL and PT G20210A mutations. Fourteen of 52 patients with thrombosis (%26.9) were detected to have a FVL mutation. The PT G20210A mutation was detected in 6 (%11) of the 52 patients. Our findings reveal that FVL and PT G20210A mutations are significantly higher in patients with DVT than in the healty population in the southeast of Turkey.
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    Protein C and antithrombin III in children with acute leukemia.
    (1993) Atlihan F.; Karakaş Z.; Batun S.
    In this study Protein C (PC) and antithrombin III (AT III) levels in childhood acute leukemia were investigated. The mean PC activity levels in 19 newly diagnosed cases of acute leukemia were significantly lower as compared with the normal controls (p < 0.05). A significant increase was found (p < 0.01) in the patients in remission. Prior to treatment 78.8 percent of patients had decreased PC activity levels, but all patients had normal PC activity during remission. Decreased PC activity levels were found to be independent of the leukocyte count and liver function. No statistically significant difference was found in the AT III antigen levels between the untreated patients, the patients in remission and the control group. Our results indicate that apart from thrombocytopenia, low PC activity levels and alterations in fibrinolysis and coagulation may be responsible for the hemorrhagic manifestations observed in cases of acute leukemia.
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    Quantitative analysis of t(8,21) and inv(16) via RT-PCR in patients with acute myeloid leukemia
    (2005) Ayyildiz O.; Kalkanli S.; Batun S.; Işikdo?an A.; Söker M.; Yurt M.; Müftüo?lu E.
    It has been showed that there is a relation between chromosomal abnormality and prognosis in acute myeloid leukemia (AML). There are many chromosomal abnormalities in AML patients and it is known that t(8;21) and inv(16) are good prognostic abnormalities. Recently the treatment has been planned according to these abnormalities. We investigated t(8,21) and inv(16) abnormalities by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) in 19 patients with AML. Morever conventional cytogenetic method was applied for all patients. Of whom 9 were men and 10 women. Age of avarage was 19 to 58 years. FAB morphologic classification follows as; 5 AML-M1, 8 AML-M2, 5 AML-M4, 1 AML-M5. Complete remission was obtained in eighteen patients with first induction regimen, whereas in one patient after second induction. t(8;21) has been found in 1 patient with cytogenetic method and confirmed with RT-PCR. In this study, we aim to search t(8;21) and inv(16) abnormalities in AML cases.