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    Assessment of serum asymmetric dimethylarginine levels and left ventricular diastolic function in patients with ankylosing spondylitis
    (Wiley, 2017) Inci, Umit; Yildiz, Abdulkadir; Batmaz, Ibrahim; Tekbas, Ebru
    Aim: To assess left ventricular diastolic functions and serum dimethylarginine (ADMA) concentrations, as well as the effect of different treatment strategies on ADMA concentrations and diastolic function parameters, in patients with ankylosing spondylitis (AS). Method: Sixty AS patients and 40 control subjects without classical cardiovascular (CV) risk factors were included in the study. Baseline clinical and echocardiographic variables were obtained. C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and ADMA levels were measured. Spinal mobility, disease activity and functional status were assessed using Bath Ankylosing Spondylitis Metrology Index, Bath Ankylosing Spondylitis Disease Activity Index and Bath Ankylosing Spondylitis Functional Index. Results: CRP, ESR and ADMA levels were significantly higher in the AS group as compared to the control group. Two (5%) control subjects and six (10%) AS patients met the criteria for left ventricular diastolic dysfunction (DD) on conventional Doppler echocardiography, but the difference was not statistically significant (P = 0.36). However, using tissue Doppler imaging, 12 (20%) patients in the AS group and three (8%) subjects in the control group were diagnosed with left ventricular DD (P = 0.08). The anti-tumor necrosis factor (TNF)-alpha group, conventional therapy group and control group were compared in terms of ADMA, CRP, ESR levels and echocardiographic parameters. ADMA levels were significantly lower in anti-TNF-alpha group as compared to the conventional therapy group (P < 0.001). In the control group, ADMA levels were significantly lower than both treatment groups (P < 0.001). Conclusion: Increased ADMA levels reveal impaired nitric oxide metabolism in a relatively young group of patients with AS, who have no classical CV risk factors. Anti-TNF-alpha may have beneficial effect on endothelial function in AS patients by reducing ADMA levels.
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    Association between Serum Follistatin-Like Protein 1 Levels and Disease Activity in Behçet's Disease
    (Georg Thieme Verlag Kg, 2023) Demir, Mesut; Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Ekinci, Aysun; Akar, Zeynel Abidin; Batmaz, Oznur; Karakoc, Mehmet
    Introduction This study sought to determine the serum levels of follistatin-like protein 1 (FSTL-1), a glycoprotein of mesenchymal origin shown to be involved in the pathogenesis of many inflammatory diseases, for example Behcet's disease (BD), and to investigate its association with disease activity.Material and Methods The study included 45 patients followed for newly diagnosed Behcet's disease who met the 1990 International Study Group criteria for BD and a control group of 36 healthy volunteers who were age- and gender-matched. Peripheral blood samples were collected from the patients and control groups. Serum FSTL-1 levels were measured using an enzyme-linked immunosorbent assay. The disease activity was assessed using the Behcet's Disease Current Activity Form (BDCAF).Results A comparison of serum FSTL-1 levels in the patient and control groups found significantly higher levels of FSTL-1 in the patient group. Serum FSTL-1 levels were significantly higher in female patients compared with male patients. Female patients exhibited significantly higher BDCAF scores compared with male patients (p=0.008). Erythrocyte sedimentation rate and serum FSTL-1 levels were positively correlated.Conclusion Serum FSTL-1 levels may play a role in the aetiopathogenesis of BD and can also be a useful biomarker for determining disease activity.
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    The association between varicocele and ankylosing spondylitis via color duplex sonography
    (Springer, 2014) Hamidi, Cihad; Batmaz, Ibrahim; Gumus, Hatice; Penbegül, Necmettin; Cetincakmak, Mehmet Guli; Tahtasiz, Mehmet; Bilici, Aslan
    Objective To evaluate the relationship between varicocele and ankylosing spondylitis (AS) via color duplex sonography (CDS). Methods Thirty male patients (age range 18-40 years, mean age 30.27 years) with AS and 30 male healthy controls (age range 20-36 years, mean age 27.23 years) were evaluated for varicocele using CDS. Results Vein diameter in right and left pampiniform plexus (PP) in the AS group was significantly higher than in the control group (p < 0.001 and p = 0.003, respectively). The incidence of varicocele was observed as 33.3 % in the AS group and 10 % in the control group. However, the difference was statistically significant (p = 0.028). The rate of right, left, and bilateral varicocele was 3.3 % (1 patient), 23.3 % (7 patients), and 6.6 % (2 patients), respectively, in the AS group, versus 0, 10, and 0 % in the control group (p = 1.000, p = 0.166, and p = 0.492, respectively). Conclusions The incidence of varicocele in AS patients is higher than in control subjects, and the difference is statistically significant. Therefore, varicocele must be taken into consideration and investigated in patients with AS.
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    Association of Neuron-Specific Enolase with Sleep Quality, Cognitive Function And Quality of Life in Patients with Fibromyalgia Syndrome
    (Clinical & Exper Rheumatology, 2014) Verim, Sabahattin; Cavas, Husamettin; Nas, Kemal; Yazmalar, Levent; Batmaz, Ibrahim; Cevik, Remzi
    [Abstract Not Available]
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    A case of brucellar spondylodiscitis involving the cervical spine
    (Ios Press, 2009) Nas, Kemal; Bukte, Yasar; Ustun, Cemal; Cevik, Remzi; Geyik, Mehmet Faruk; Batmaz, Ibrahim
    We have presented a patient of 71-year-age with brucellar spondylodiscitis, involving the cervical spine, especially the C3-C4 segment. The patient had painful percussion of the cervical spine and passive mobilization of the neck, decreased range of motion, and cervical paravertebral tenderness; but no abnormalities observed on neurological examination. Wright agglutination test for brucella was positive at 1/320. Cervical localization for brucellar spondylodiscitis is an unusual case and should be detected and treated as early as possible. In endemic regions, spinal involvement of brucellosis should be considered in cases with fever, neck and low back pain.
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    A Case of Spondyloepiphyseal Dysplasia Tarda Coexisting With Osteoporosis and Mimicking Spondyloarthropathy
    (Galenos Yayincilik, 2013) Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Dilek, Banu; Ulu, Mehmet Ali; Verim, Sabahattin; Budulgan, Mahmut; Cevik, Remzi
    Spondyloepiphyseal dysplasia tarda (SEDT), which is characterized by short stature with short trunk, may cause barrel chest, kyphoscoliosis, platyspondyly, coxa vara and genu varum/valgum deformities due to delayed formation of epiphyses. The association of SEDT with osteopenia and osteoporosis has been reported. Chronic back and buttock pain, swelling of the joints and morning stiffness are some of the clinical findings of SEDT which can be confused with inflamatory diseases. In this article, we present a 19-year-old male patient with SEDT who was diagnosed as having spondyloarthropathy because of back and buttock pain and morning stiffness associated with osteoporosis.
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    A Case With Type I Gaucher Primarily Involved Pelvis
    (Elmer Press Inc, 2012) Dilek, Banu; Aydin, Fatma; Dag, Ilknur Sevin Buluttekin; Batmaz, Ibrahim; Nas, Kemal; Cevik, Remzi
    Type 1 Gaucher disease is the most common lysosomal storage disorder which also affects the musculoskeletal system with various organ manifestations. Here, we aimed to present a case diagnosed Type 1 Gaucher disease which mainly involved pelvis.
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    Comparison of clinical outcomes of ultrasonography-guided and blind local injections in facet syndrome: A 6-week randomized controlled trial
    (Ios Press, 2020) Karkucak, Murat; Batmaz, Ibrahim; Kerimoglu, Servet; Ayar, Ahmet
    BACKGROUND: Facet syndrome is defined as pain that arises from any structure of the facet joints, including the fibrous capsule, synovial membrane, hyaline cartilage, and bone. OBJECTIVES: To compare the effectiveness of US-guided and blind injections on clinical outcome in facet syndrome. MATERIALS AND METHODS: Forty-seven patients with the diagnosis of facet syndrome were included. Patients were consecutively randomized into one of the two groups. The patient's history, physical examination and routine laboratory parameters were obtained and diagnose was established based on physical findings. Two injections (mixture of 2 ml of 1% lidocaine hydrochloride and 20 mg of triamcinolone, to a single or maximum two sites depending on the clinical characteristics of the facet joint) were performed with 15 days apart, as blinded or US-guided manner. Clinical outcome assessments were carried out at 0, 2nd and 6th weeks, using Visual Analog Scale (VAS), Oswestry Disability Index (ODI) and State-Trait Anxiety Inventory (STAI). RESULTS: The patients' initial VAS and ODI were not significantly different. When the two groups were compared in the 6th week in terms of VAS scores, improvement was more pronounced in the US-guided injection group (US-guided group (n = 23) before 7.6 (2.2) cm, after 3.0 (1.7) cm, P = 0.0001 vs blind group (n = 24) before 7.2 (1.3) cm, after 5.2 (2.0) cm, P = 0.0001). The improvement in initial and 6th week ODI was statistically significant in the US-guided injection group ( P = 0.006). Except STAI I for US-group, trait anxiety scale scores were significant in both groups. CONCLUSION: The US-guided local injections offer better clinical outcome in the treatment of facet syndrome.
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    Depressive and Anxious Temperaments in Patients with Complex Regional Pain Syndrome Secondary to Tendon Injury
    (Taylor & Francis Ltd, 2014) Batmaz, Ibrahim; Dilek, Banu; Sariyildiz, Mustafa Akif; Erbatur, Serkan; Bez, Yasin; Yazmalar, Levent; Bozkurt, Mehtap
    Objective: To determine the affective temperaments and somatoform amplification of the symptoms and its relation with the complex regional pain syndrome [CRPS] in patients who had tendon injuries of the forearm and hand. Methods: Sixty-seven patients [60 males, 7 females] with a forearm or hand tendon injury were enrolled in the present study. The patients were divided into two groups: CRPS and non-CRPS. The patients' pain levels within the last 48 hours were assessed using the visual analog scale [VAS]. The temperament of the patients was evaluated using the Temperament Evaluation of Memphis, Pisa, Paris and San Diego Auto questionnaire [TEMPS-A]. Their anxiety levels were evaluated with the help of the State-Trait Anxiety Inventory [STAI]. The depression assessment was performed using the Beck Depression Inventory [BDI]. The Somato sensory Amplification Scale [SSAS] was employed for the evaluation of the somatoform disorders. Results: The mean age of the patients was 26.21 +/- 8.01 years [age range: 18 to 57 years]. Among the patients 24 [35.8%] had developed CRPS. When the patients with and without CRPS were compared in terms of their psychological scores, the STAI-II and BDI scores were observed to be significantly deteriorated in the CRPS group in comparison to the non-CRPS group [p<0.05]. Among the TEMPS-A subtypes, anxious [16.7%] and depressive [41.7%] temperaments were more dominant in the CRPS group and the ratio was significantly more deteriorated than the non-CRPS group [p<0.05]. No significant difference was observed between the groups regarding the SSAS scores [p>0.05]. Conclusion: The present study is the first one evaluating the affective temperaments of CRPS patients with tendon injury, and the main findings point out that depressive and anxious temperaments are the most common dominant affective temperaments among our patients.
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    Education and Visual Information Improves Effectiveness of Ultrasound-Guided Local Injections on Shoulder Pain and Associated Anxiety Level A Randomized Controlled Study
    (Lippincott Williams & Wilkins, 2016) Karkucak, Murat; Cilesizoglu, Nurce; Capkin, Erhan; Can, Ipek; Batmaz, Ibrahim; Kerimoglu, Servet; Onder, Mustafa Avni
    Objective Local injections are widely used in patients with a painful shoulder. The aim of this study was to evaluate the possible impact of patients' visual information on the effectiveness of ultrasound (US)-guided local injections on anxiety levels and shoulder pain. Design A total of 151 patients, scheduled for local injection owing to shoulder pain, were randomly assigned into two groups in a consecutive order. Patients in group I (n = 72) were provided information related to US findings and allowed to watch the procedures from the monitor, whereas patients in group II (n = 79) received the injection only without any collaboration. Data were collected from both groups immediately before and after injections through visual analog scale and questionnaire (the State-Trait Anxiety Inventory [STAI] forms 1 and 2). Results US-guided local injections provided significant improvement of anxiety and pain in both groups, irrespective of providing visual information. Group I and group II comparisons with respect to the visual analog scale, STAI 1, and STAI 2 yielded significant difference only for postinjection STAI 2 in group I (P = 0.006). Intragroup comparisons revealed significant differences between preinjection and postinjection values (group I: visual analog scale, P = 0.001; STAI form 1, P = 0.001; STAI form 2, P = 0.002; group II: visual analog scale, P = 0.001; STAI form 1, P = 0.002; STAI form 2, P = 0.042). There was no significant difference between the groups in terms of postinjection satisfaction levels from the procedures (P = 0.824). Conclusions Performing US-guided shoulder injections with patient visual information provides positive contributions to coping with pain and anxiety. In particular, the patient collaboration-based US-guided injections have positive consequences on patients' long-standing trait-anxiety levels.
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    The effectiveness of transforaminal epidural steroid injections on radicular pain, functionality, psychological status and sleep quality in patients with lumbar disc herniation
    (Ios Press, 2017) Sariyildiz, Mustafa Akif; Batmaz, Ibrahim; Yazmalar, Levent; Gunes, Mehmet; Turan, Yahya
    BACKGROUND: The significance of fluoroscopy-guided transforaminal epidural steroid injections (TFESI) in the treatment of lumbar disc herniation (LDH) is well known. The aim of our study is to investigate the effectiveness of TFESI on radicular pain, functionality, psychological status, and sleep quality in patients with LDH. METHODS: Seventy-five LDH patients (36 males, 39 females) were enrolled in the study. All patients received a fluoroscopically guided TFESI (betamethasone 40 mg, lidocaine 2%). Also all patients were evaluated according to (with the visual analogue scale) radicular pain, Oswestry disability index (ODI), hospital axiety and depression scale, and Pittsburgh sleep quality index (PSQI) at baseline, at two weeks, and 12 months post injections. RESULTS: Mean age was 46.4 +/- 12.5. When compared to baseline measurements there were significant improvements in radicular pain, ODI, modified schober, Laseque angle, finger to floor distance, depressive symptoms and PSQI scores at two weeks and 12 months after injection. Improvement of at least 50% in radicular pain relief, ODI score and sleep quality index was detected at two weeks 83%, 71%, 69% respectively. This rate showed regression at 12 months of 73%, 65% and 62% respectively. Duration of symptoms was significantly negatively correlated with changes in scores of radicular pain, ODI, depressive symptoms, and PSQI. There were no significant correlations with symptom duration and anxious symptoms. CONCLUSION: Fluoroscopy guided TFESI had positive effects on radicular pain, functionality, depressive symptoms and sleep quality in management of LDH.
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    Efficacy of Pulsed and Continuous Therapeutic Ultrasound in Myofascial Pain Syndrome A Randomized Controlled Study
    (Lippincott Williams & Wilkins, 2015) Ilter, Leman; Dilek, Banu; Batmaz, Ibrahim; Ulu, Mehmet Ali; Sariyildiz, Mustafa A.; Nas, Kemal; Cevik, Remzi
    Objectives This study aimed to compare continuous and pulsed ultrasound therapy with sham ultrasound in terms of pain, severity of muscle spasm, function, depression, and quality of life in patients with myofascial pain syndrome. Design Patients were randomly divided into three groups, including the continuous ultrasound group (3 MHz, 1 W/cm(2), n = 20), the pulsed ultrasound group (3 MHz, 1 W/cm(2), 1:1 ratio, n = 20), and control group (sham, n = 20). The primary outcome measures were severity of pain at rest and during activity (visual analog scale, 0-10 cm). The secondary outcome measures were function (Neck Pain and Disability Scale), depressive mood (Beck Depression Scale), and quality of life (Nottingham Health Profile). All evaluations were performed at baseline, after treatment, and at the 6th and 12th wks. Results All three groups had significant improvements in all of the pain scores, the severity of muscle spasms, function assessments, and certain subparameters of the quality of life scale (P < 0.05). The continuous ultrasound group had significantly greater improvements in pain at rest (P < 0.05). However, no statistically significant differences were observed in the other parameters (P > 0.05). Conclusions Continuous ultrasound therapy is more efficient in reducing pain at rest for myofascial pain syndrome patients than is sham or pulsed ultrasound therapy.
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    Efficiency of therapeutic ultrasound on pain, disability, anxiety, depression, sleep and quality of life in patients with subacromial impingement syndrome: A randomized controlled study
    (Ios Press, 2016) Yazmalar, Levent; Sariyildiz, Mustafa Akif; Batmaz, Ibrahim; Alpayci, Mahmut; Burkan, Yahya Kemal; Ozkan, Yasemin; Okcu, Mehmet
    BACKGROUND: Subacromial impingement syndrome (SIS) is characterized by pain and disability of shoulder. Various treatment methods have been used for SIS. OBJECTIVES: The aim of our study was to evaluate efficacy of therapeutic ultrasound (US) on pain, disability, anxiety, depression, sleep quality and quality of life in patients with SIS. METHODS: Patients with SIS were randomly divided into two groups, including the group 1 (continuous US group; 3 MHz, 1.5 W/cm(2), n = 26) and group 2 (sham US group, n = 24). Additionally, transcutaneous electrical nerve stimulation (TENS) + exercise program were added in both groups. Pain and disability of the shoulder were assessed by the Shoulder Pain and Disability Index (SPADI), while anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality. Quality of life was evalutaed by the Nottingham Health Profile (NHP). Patients were evaluated at baseline and after end of three weeks. RESULTS: Both groups had significantly improvements in terms of SPADI-pain, SPADI-disability, SPADI-total, NHP-pain and NHP-sleep scores after the three weeks interventions. There were significantly improvements in the Group 1 in terms of PSQI-total, and NHP-physical activity. Group 2 had significantly improvements in terms of anxiety-HADS, depression-HADS and NHP-emotional reaction scores. In the inter-group comparison, there were no significantly differences in the change scores were observed in any domains of SPADI scores, anxiety, depression and sleep scores, or any NHP scores. CONCLUSIONS: Our study showed that US does not have any benefits on SIS. TENS + exercise program are not effective on anxiety, depression and fatigue, however TENS + exercise program are effective on pain, disability and sleep disturbance in patients with SIS.
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    Evaluation Of The Relationship Of Kinesiophobia With Anxiety, Upper Extremity Disability And Quality Of Life In Patients With Frozen Shoulders
    (Georg Thieme Verlag Kg, 2023) Batmaz, Oznur Uysal; Yakar, Burkay; Mirzaoglu, Tacettin; Yilmaz, Ahmet; Em, Serda; Batmaz, Ibrahim
    Introduction Frozen shoulder is a painful shoulder disease in which glenohumeral joint movements are actively and passively restricted in all directions. If not treated, it can cause various psychological diseases and muscle and joint diseases. Kinesiophobia; this is defined as a fear of physical activity resulting from excessive sensitivity and an uncomfortable feeling due to painful or repeated injury. In this study, it was aimed to evaluate the relationship of kinesiophobia to upper extremity disability, anxiety and quality of life in patients with frozen shoulder.Materials and methods Firat University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, between September 2020 and March 2021; As a result of clinical evaluation and radiological examinations, patients were enrolled between the ages of 18-75 and who agreed to participate in the study; 48 patients were diagnosed with frozen shoulder and met the inclusion and exclusion criteria of the study and were included in the patient group; Fourty healthy subjects aged between 18-75 years, who did not have shoulder disease and who met the inclusion and exclusion criteria of the study, were included in the control group. A total of 88 cases were included in the study. The following scales were used. TAMPA kinesiophobia scale to assess kinesiophobia in patients and control group, Beck Anxiety scale to assess anxiety in patient group; The Disabilities of The Arm, Shoulder and Hand (DASH) scale to assess upper extremity disability; Short Form (SF)-36 was used to assess quality of life.Results TAMPA kinesiophobia scale was found to be significantly different in the patient group when the patient group and control group were compared. According to the correlation analysis, the TAMPA kinesiophobia scale showed a positive correlation with the Beck-Anxiety and DASH scales in the patient group, while a negative correlation was found with the SF36-Physical function, emotional role difficulty and social functionality.Conclusion In patients with frozen shoulder, kinesiophobia seems to be associated with increased anxiety and upper extremity disability, as well as low quality of life. Structural disorders as well as psychological factors should be taken into account among the reasons for the prolonged limitation of movement and delayed recovery. When the physicians serving in the primary care are experienced with patient management with frozen shoulder, as evaluated for therapeutic purposes, planning psychological support treatments in addition to medical and physical therapy will increase the quality of health care provided to patients.
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    Fibromyalgia incidence among patients with hepatitis B infection
    (Wiley, 2016) Yazmalar, Levent; Deveci, Ozcan; Batmaz, Ibrahim; Ipek, Davut; Celepkolu, Tahsin; Alpayci, Mahmut; Hattapoglu, Erkam
    Aim: The purpose of our investigation was to evaluate the incidence of fibromyalgia syndrome (FMS) and identify FMS-related clinical symptoms in hepatitis B virus (HBV) patients. Methods: One hundred and eighteen HBV surface antigen (HbsAg)-positive patients (40 with chronic active hepatitis B, 40 hepatitis B carriers and 38, all of whom had been antiretroviral-treated for at least 3 months) were included in this study. In addition, 60 age- and gender-matched HbsAg-negative healthy controls were included in the study. Results: There was no significant difference in age, gender or body mass index (BMI) between the two groups (P > 0.05). Serum aspartate aminotransferase and alanine aminotransferase levels were significantly higher in HBV patients relative to the control group (P < 0.05). The incidence of FMS, widespread body pain, fatigue, sleep disturbance, anxiety, morning stiffness, arthralgia was significantly greater among HBV patients relative to the control group. Additionally, the mean tender point counts and the visual analog scale values were significantly higher among the HBV patients (P < 0.05). Conclusions: The results of the present study demonstrate that FMS incidence is greater among HBV patients relative to control subjects. However, there were no differences in FMS incidence among the subgroups of HBV diagnoses.
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    HIGH OCCURRENCE OF METABOLIC SYNDROME IN PATIENTS WITH RHEUMATOID ARTHRITIS
    (Oxford Univ Press, 2011) Karakoc, Mehmet; Batmaz, Ibrahim; Tahtasiz, Mehmet; Nas, Kemal; Cevik, Remzi; Tekbas, Ebru; Yildiz, Ismail
    [Abstract Not Available]
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    HLA-DRB1 Alleles Distribution in Patients With Rheumatoid Arthritis in A Tertiary Center in the Southeastern Anatolia Region of Turkey
    (Galenos Yayincilik, 2013) Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Dilek, Banu; Yildiz, Ismail; Nas, Kemal; Ayyildiz, Orhan; Cevik, Remzi
    Objective: The HLA-DRB1 alleles play an important role in the genetic predisposition to rheumatoid arthritis (RA). The relationship between HLA-DRB1 and rheumatoid arthritis show differences according to various ethnic groups and geographical distributions. The aim of this study was to determine the distribution of HLA-DRB1 among the Turkish RA patient population in the Southeastern Anatolia Region. Materials and Methods: 96 patients diagnosed with RA and a control group consisting of 84 healthy individuals were enrolled in the study. The HLA-DRB1 type and subtypes were specified using the polymerase chain reaction with sequence specific primers (PCR-SSP) method. The between-group HLA-DRB1 type and certain subtype frequencies were compared. Results: The DRB1*10 alleles were found to be statistically significantly higher in patients with RA compared to the control group (p=0.001). However, the DRB1*07 and DRB1*11 alleles were statistically significantly lower in patients with RA (p<0.001 and p=0.02, respectively). In the RA patient group, the DRB1*0401, DRB1*0408 and DRB1*1001 subtypes were found to be statistically significantly higher (p=0.04, p=0.01, p=0.005, respectively), while the DRB1*0402, DRB1*0403 and DRB1*0701 subtypes were statistically significantly lower (p=0.01, p=0.02, p<0.001, respectively). Conclusion: This study has revealed the HLA-DRB1 distribution in the Southeastern Anatolia Region of Turkey. DRB1*10 type and DRB1*0401, DRB1*0408, DRB1*1001 subtypes were observed to be related with RA. DRB1*07, BRB1*11 types and DRB1 *0402, DRB1*0403, DRB1*0701 subtypes were accepted as protective alleles and subtypes.
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    HLA-DRB1 EXPRESSION IN THE RHEUMATOID ARTHRITIS PATIENTS AMONG THE POPULATION IN THE SOUTHEAST ANATOLIAN REGION OF TURKEY
    (Oxford Univ Press, 2012) Batmaz, Ibrahim; Sariyildiz, MehmetAkif; Dilek, Banu; Yildiz, Ismail; Ayyildiz, Orhan; Nas, Kemal; Cevik, Remzi
    [Abstract Not Available]
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    Investigation of the Effects of Leptin on the Cardiovascular System in Patients With Systemic Sclerosis
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2013) Atilgan, Zuhal Ariturk; Islamoglu, Yahya; Tekbas, Ebru; Budulgan, Mahmut; Batmaz, Ibrahim; Tahtasiz, Mehmet; Yuksel, Hatice
    Objective: Cardiac involvement in systemic sclerosis can be seen, and often remains silent. Leptin, which is often associated with hypertension and regulation of sympathetic tone, has been reported to contribute to the development of atherosclerosis, endothelial dysfunction and thrombosis by acting directly. The aim of this study was to investigate the effects of leptin on the cardiovascular system in patients with systemic sclerosis. Materials and Methods: Twenty-seven patients with systemic sclerosis and 28 healthy subjects as a control group were included in the study. Clinical and laboratory parameters, 24-hour Holter ECG and ambulatory blood pressure monitorings were recorded and serum leptin levels were measured in all subjects. Results: Mean leptin levels were lower in patients with systemic sclerosis than in controls. In 24-hour ambulatory blood pressure Holter recordings, the mean systolic and diastolic blood pressure, daytime systolic and diastolic blood pressure, systolic and diastolic blood pressure values at night were lower in patients when compared with controls. There was no relationship between leptin and heart rate variability parameters. A positive correlation was found between leptin levels and 24-hour ambulatory blood pressure parameters. Conclusion: Decreased serum leptin levels and increased mean heart rate in patients with systemic sclerosis may be the result of increased sympathetic tone.
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    Kinesio taping in patients with lateral epicondylitis
    (Ios Press, 2016) Dilek, Banu; Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Sahin, Ebru; Ilter, Leman; Gulbahar, Selmin; Cevik, Remzi
    BACKGROUND: Lateral epicondylitis (LE) is a painful condition that affects the tendinous tissue of the lateral epicondyle of the humerus and leads to loss of function of the affected limb. Therefore it can have a major impact on the patient's social and personal life. Many treatments are recommended for lateral epicondylitis; unfortunately the evidence is limited. OBJECTIVES: The aim of study was to investigate the effect of kinesio taping (KT) on pain, grip strength and function in patients LE. METHODS: Thirty-one (23 females, 8 males) patients with LE were included. KT was applied twice a week for 2 weeks. Pain at rest, activity of daily living (ADL), night and palpation on lateral epicondyle was evaluated with the visual analog scale (VAS 0-10 cm), and the grip strength was measured with a hand held dynamometer. The stage of the disease was evaluated by the Nirschl score and the functional status was assessed with Patient-Rated Forearm Evaluation Questionnaire (PRTEQ) score. These parameters were evaluated before, at 2 weeks and 6 weeks after treatment. Patients' satisfaction was also recorded on a Likert scale after treatment at 2 weeks and 6 weeks. RESULTS: The average age of the patients was 43.58 +/- 9.02. The dominant limb was affected in 64.5% (20) of the patients. After the application of KT on lateral epicondyle, there was a significant improvement in all parameters in terms of pain, Nirschl score, hand grip strength, patient satisfaction, and PRTEQ scores at 2 and 6 weeks. CONCLUSIONS: Kinesio taping can be an effective treatment method in LE. This application improves pain, grip strength and functional status of the patients with LE.