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Öğe Endovascular Embolization in Management of Vaginal Bleeding(Galenos Yayincilik, 2007) Bayrak, Aylin Hasanefendiolu; Bas, Ahmet; Cantasdemir, Murat; Numan, FuruzanObjective: To investigate results and effectiveness of endovascular embolization in treatment of massive or intractable vaginal bleeding. Materials and Methods: Between 1991 and 2004, 9 patients with vaginal bleeding, ranging in age from 28 to 53 years (mean; 45.3 years) were treated with endovascular embolization therapy. The causes of massive vaginal bleeding were gynecological malignancy in 8 cases, and arterial pseudoaneurysm formation following postpartum subtotal hysterectomy in 1 case. We used polyvinyl alcohol (PVA) particles in cases of gynecological malignancies, and Gelfoam in the postpartum case as embolizing agents. The results were retrospectively analysed. Results: Diagnostic angiograms demonstrated tumoral blush in all cases with pelvic malignancies fed by the branches of both internal iliac arteries. In the obstetric case, a pseudoaneurysm at lateral wall of the cervix and the vaginal cuff was the source of bleeding. The embolization procedures were technically successful and vaginal bleeding was controlled after embolization in all cases. In two cases, with gynecological malignancy, 20% and 30% residual tumoral blush were seen, respectively. The latter case rebleeded after 4 months, and re-embolization was performed successfully. In all other cases, there were no recurrent vaginal bleeding. Discussion: Endovascular embolization is a safe and effective treatment in massive or intractable vaginal bleeding. Because of various factors (lower mortality and morbidity rates, preservation of surgical options even after unsuccessful embolization), endovascular embolization should be kept in mind as a first treatment modality.Öğe Evaluation of short estrus synchronization methods in dairy cows(Elsevier, 2008) Cirit, Uemuet; Bacinoglu, Suleyman; Tas, Muzaffer; Demir, Kamber; Bas, Ahmet; Ak, Kemal; Ileri, Irfan KamuranIn the present study, two new short estrus synchronization methods have been developed for lactating dairy cows. The study was completed in three consecutive phases. In experiment (Exp) 1, 32 cows, that were not detected in estrus since calving between the 50th and 84th post-partum days, were treated with PGF2 alpha (PGF, D-Cloprostenol, 0.150 mg), estradiol propionate (EP, 2 mg) and GnRH (lecirelina, 50 mu g) at 24 h intervals, respectively, and timed artificial insemination (TAI) was performed 48 h after PGF. Different from Exp 1, EP and GnRH were given at 48 and 60 h, respectively after PGF in Exp 2 (n = 20), instead of 24 and 48 h. Ovulations were investigated by ultrasound for 7 days starting from the day of PGF treatment, and ovulation rates were compared with the ones obtained in Exp 1. In Exp 3, cows were given the same treatments as Exp 2, but treatments started at certain estrus stages. Cows detected in estrus and with a confirmed ovulation (n = 27) after the second PGF given 11 days apart were assigned to three treatment groups. Treatment was initiated at Day 3 (group metestrus, n = 9), Day 12 (group diestrus, n = 9) and Day 18 (group proestrus, n = 9) after ovulation. All cows included in Exp 3 were TAI between 16 and 20 h after GnRH treatment. In Exp 2 and 3, blood samples were obtained once every 2 days, starting from Day 0 to the 10th day after GnRH injection, and once every 4 days between the 10th and the 22nd days after GnRH to examine post-treatment luteal development. During the study, animals exhibiting natural estrus were inseminated and served as controls (n = 85). The rate of estrus was found to be significantly higher in cows with an active corpus luteum (CL) at the start of Exp 1 (72.7% vs. 30.0%, P < 0.05) and the pregnancy rate tended to be higher than cows without an active CL (40.9% vs. 10.0%, P = 0.08). Compared to those in Exp 1, cows in Exp 2 had higher rates of synchronized ovulation (94.1% vs. 59.1%, P = 0.013), In Exp 3, estrus (P < 0.001) and pregnancy rates (P = 0.01) were found to be significantly higher in cows in the proestrus group than in those in the metestrus group. Comparable pregnancy rates were obtained from the first and second inseminations in Exp 1 and 3 with results from those inseminated at natural estrus (P > 0.05). It was concluded from the study that the treatment in Exp 1 and 3 could result in comparable pregnancy rates after timed Al of lactating dairy cows at random stages of the estrus cycle relating to those inseminated at natural estrus, but the stage of the estrus cycle can have significant effects on pregnancy rates. (C) 2007 Elsevier B.V. All rights reserved.Öğe Occult bleeding of small bowel: endovascular embolization and literature review(Wiley, 2009) Bayrak, Aylin Hasanefendioglu; Cantasdemir, Murat; Bas, Ahmet; Numan, Furuzan[Abstract Not Available]
