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Öğe An investigation of the effects of the local use of 1:25 dihydroxycholecalciferol (1:25 D) on tension sites during experimental tooth movement in rats.(1996) Baran S.; Hamamci O.; Akalar M.The aim of this work was to investigate the local effects of 1:25 dihydroxychole-calciferol, one of the most potent osteoclastic activity stimulants. Tests were conducted on 32 Wistar albino rats divided into 3 groups: an experimental (appliance + drug, n = 11), control (appliance only, n = 11) and a no therapy group (n = 10) which was used for purposes of interpreting histological findings in the others. A significantly higher area of unilateral apposition, relative to the control group, was observed in the experimental group local to the area of administration of the 1:25 D.