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    İskeletsel III.sınıf malokluzyonlu bireylerde ortopedik ve ortodontik tedavi sonrası yumuşak doku değişimleri
    (1998) Kama, Jalan Devecioğlu; Baran, Sedat; Darı, Osman
    Araştırmamızın amacı, maksiller darlık ve maksiller retrüzyonla karakterize, iskeletsel KI III olgularda maksiller ekspansiyon ve protraksiyon sonucunda oluşan yumuşak doku değişikliklerini incelemektir. Araştırmamızın materyalini, Dicle Üniversitesi Dişhekimliği Fakültesi Ortodonti Anabilim Dalına tedavi için başvuran 30 iskeletsel KI III anomaliye sahip hasta oluşturmuştur. Hastaların 15'ine maksiller ekspansiyon ve protraksiyon tedavisi uygulanmış, diğer 15 tedavi edilmeyen hasta ise kontrol grubunu meydana getirmiştir. Hastaların lateral sefalometrik radyografileri üzerinde elde edilen ölçümlerin grup içi karşılaştırılması Wilcoxon testi ile, gruplar arası farklılıkların önemi ise Mann-Whitney U testi ile değerlendirilmiştir. Tedavi grubunda yüz açısının düşüşü p<0.001 düzeyinde, total yumuşak doku konveksitesi ve Ls-E boyutundaki azalma p<0.001 düzeyinde, üst dudak uzunluğunda p<0.05 düzeyinde artış görülmüştür. Kontrol grubunda burun yüksekliğindeki artış p<0.01 düzeyinde anlamlıdır. Sonuç olarak erken dönemde maksiller ekspansiyon ve protraksiyon tedavisi ile fasiyal profilde önemli değişiklikler elde edilmektedir.
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    Öğe
    Orthodontic and orthopaedic changes associated with treatment in subjects with Class III malocclusions
    (Oxford Univ Press, 2006) Kama, Jalen Devecioglu; Oezer, Toeruen; Baran, Sedat
    The aim of this study was to determine the cephalometric changes in subjects with Class III malocclusions after rapid palatal expansion (RPE) and facemask treatment. The 30 subjects presented with developing Class III malocclusions. The treatment group comprised 15 patients ( eight girls and seven boys, mean age 11 years 6 months) who had undergone RPE and facemask therapy. The control group consisted of nine girls and six boys with a mean age of 11 years 8 months. Radiographs were taken at the same time intervals for both groups, and the average treatment time was 15 months. A Wilcoxon test was used to determine significant differences before and after treatment, and a Mann-Whitney U-test to analyse differences between the treatment and control groups. In the sagittal plane, significant changes were observed in both groups. In the treatment group, the following dimensions increased significantly: A perpendicular to FHp (P < 0.001), ANS-PNS (P < 0.01), 6 perpendicular to FHp (P < 0.05); in the control group Go-Gn (P < 0.05) increased significantly. In the treatment group, SN/Go-Gn and SN/ ANS-PNS had higher values and this finding was significant (P < 0.05). Managing developing Class III malocclusions with RPE and maxillary protraction presents favourable results, such as vertical and sagittal displacement of point A.
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    Ultrastructural evaluation of the effects of cinnamon on the nervus ischiadicus in diabetic rats
    (Riyadh Armed Forces Hospital, 2009) Bahceci, Selen; Aluclu, Mehmet U.; Canoruc, Naime; Bahceci, Mithat; Akkus, Murat; Baran, Sedat; Gokalp, Deniz
    Objective: To investigate the effects of oral cinnamon supplementation on the nervus ischiadicus at the electron microscopical level in rats. Methods: This study was performed between 20042006 in Dicle University School of Medicine, Diyarbakir, Turkey in 15 adult Sprague-Dawley rats. Rats were divided into 3 groups; control (C) (n=5), diabetic without cinnamon (D) (n=5), and diabetic with cinnamon (D-C) (n=5). Diabetes was induced with intraperitoneal alloxan administration. All diabetic rats were treated with human insulin. AN rats were fed with standard pellet chow. The D-C group rats were fed with standard pellet chow plus Cinnamomum cassia at the dose of 400mg/kg. All rats were sacrificed after 3 months and we obtained the nervus ischiadicus of all rats. Contrast stained thin sections evaluated by Jeol-TEM-1010 electron microscope, were not statistically different in both groups and photo samples were obtained. Results: Mean blood glucose, hemoglobin AlC, and lipid profile were not statistically different in both groups. Marked detachment of myelin lamellae at Schmidt-Lanterman clefts, lysis in cristae mitochondrialis and degenerative changes, severe dispersion of organelles in neurolemma, mesoaxon region, and remarkable edema at the endoneurium were found in diabetic rats. On the contrary, mesoaxon, nucleus, nucleolus and myelin sheet were almost of normal appearance at the ultra-structural level in the D-C group. Conclusions: Cinnamon extracts may have beneficial effects on the development of diabetic neuropathy in alloxan induced diabetic rats.