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  1. Ana Sayfa
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Yazar "Baran, Mehmet Firat" seçeneğine göre listele

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    Analysis of bioactive compounds using LC-ESI-MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
    (Wiley, 2023) Aktepe, Necmettin; Baran, Ayse; Atalar, Mehmet Nuri; Baran, Mehmet Firat; Keskin, Cumali; Taskin, Abdullah; Yavuz, Oemer
    Cyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C. origanifolium were investigated. In the extracts, phenolic compound analysis by the liquid chromatography-electrospray ionization-tandem mass spectrometry method, antimicrobial effect by the minimum inhibition concentration method, and cytotoxic effect on human dermal fibroblasts (HDF), glioblastoma cell (U87), ovarian adenocarcinoma cell (Skov-3), and human colorectal adenocarcinoma cell (CaCo-2) cancer cell lines were investigated. Cytotoxicity analyses were performed by the MTT method. In addition, the GST and AChE enzyme activities of the extracts were also measured. Around 18 compounds were detected in both the methanol and ethanol extract. It was found that the best antimicrobial effect on Gram-negative Pseudomonas aeruginosa was on methanol extract, while the ethanol extract was on Candida albicans fungus (respectively, 2.50 mg/ml, 5.0 mu g/ml). A 500 mu g/ml of methanol extract has been shown to have cytotoxic activity high effect on HDF cells. GST and AChE activity were found to decrease in a concentration-dependent manner.
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    Öğe
    Economic fast synthesis of olive leaf extract and silver nanoparticles and biomedical applications
    (Taylor & Francis Inc, 2022) Atalar, Mehmet Nuri; Baran, Ayse; Baran, Mehmet Firat; Keskin, Cumali; Aktepe, Necmettin; Yavuz, Omer; Kandemir, Sevgi Irtegun
    In this study, silver nanoparticles (AgNPs) were synthesized economically and simply using an environmentally friendly method with the extract obtained from agricultural waste olive leaves. AgNPs synthesized according to the analysis data were determined to have maximum absorbance at 433.5 nm wavelength, spherical appearance, 7.2 nm crystal nano size and -19.9 mV zeta potential. It was determined by the microdilution method with Minimum Inhibition Concentration (MIC) that AgNPs exert a suppressive effect on the growth of pathogen gram-negative, positive bacteria and yeast at very low concentrations. The cytotoxic effects of the particles were investigated on healthy cell lines (HDF) and cancerous cell lines (U118, CaCo-2, Skov-3). AgNPs showed up to 70% suppression in cancer cell lines.
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    Öğe
    Energy use efficiency and greenhouse gas emissions (GHG) analysis of garlic cultivation in Turkey
    (Chinese Acad Agricultural Engineering, 2023) Baran, Mehmet Firat; Demir, Cihan; Elicin, Ahmet Konuralp; Gokdogan, Osman
    This study has been conducted with the purpose of determining energy use efficiency and greenhouse gas emissions of garlic cultivation during the 2020-2021 cultivation season in Adiyaman province of Turkey. Questionnaires, observations and field works were performed in 134 garlic farms in the region through simple random method. In garlic cultivation, energy input was calculated as 32 103.20 MJ/hm2 and energy output was calculated as 30 096 MJ/hm2. With regards to the three highest inputs in garlic production, 46.66% of the energy inputs consisted of chemical fertilizers energy (14 979.26 MJ/hm2), 11.29% consisted of farmyard manure energy (3625.71 MJ/hm2) and 10.48% consisted of human labour energy (3363.36 MJ/hm2). Energy use efficiency, specific energy, energy productivity and net energy in garlic cultivation were calculated as 0.94, 1.71 MJ/kg, 0.59 kg/MJ, and -2007.20 MJ/hm2, respectively. The total energy input consumed in garlic cultivation was classified as 27.19% direct energy, 72.81% indirect energy, 35.17% renewable energy and 64.87% non-renewable energy. Total GHG emissions and GHG ratio were calculated as 8636.60 kg CO2-eq/hm2 and 0.46 kg CO2-eq/kg, respectively.
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    Öğe
    Removal of cadmium (II) in the aqueous solutions by biosorption of Bacillus licheniformis isolated from soil in the area of Tigris River
    (Taylor & Francis Ltd, 2021) Baran, Mehmet Firat; Duz, Mehmet Zahir
    Biosorption by dead bacteria is an alternative and effective method for the removal toxic elements from drinking water and waste water. The biosorption of Cd(II) from aqueous solutions was studied in a batch method by using dead bacteria Bacillus licheniformis sp. extracted from soil in the area of Tigris River. The Cd element analysis was determined using ICP-OES and AAS. The maximum adsorption capacity of biosorbent was determined, respectively, 24.51 mg/g for Cd element from Langmuir isotherm constants in the optimum conditions. The characterisation of B. licheniformis to describe behaviour of bacteria was determined such as adsorption isotherm, kinetic and thermodynamic data using FT-IR, TGA, DTA, SEM and EDX. The results suggested that the most equilibrium data of Cd(II) bioadsorption was best represented by the pseudo second-order equation and Langmuir isotherm model at different time-temperatures. The thermodynamic functions and activation energy was found to be Delta G degrees; -0,984 kJ/mol at 318 K, Delta H degrees; 15.48 kJ/mol, Delta S degrees; 39.08 kJ/mol and E-a; 23.24 kJ/mol and due to the Delta G degrees< 0, Delta H degrees> 0, Delta S degrees> 0, the reaction mechanism was determined to be physical adsorption and endothermic. This study shows that B. licheniformis sp. can be used as an effective method for the removal of Cd(II) from aqueous solutions.
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    Öğe
    THE USE OF RAPESEED OIL METHYL AND ETHYL ESTERS AND OF RAPESEED OIL-DIESEL MIXTURES AS FUELS FOR DIESEL ENGINE
    (Parlar Scientific Publications (P S P), 2019) Elicin, A. Konuralp; Ozturk, Ferhat; Baran, Mehmet Firat; Esgici, Resat
    This study was conducted over a year period incorporating one growing seasons of 2013-2014 with the aim being to investigate the effects of the free fatty acid and yield characteristics of different rapeseed genotypes planted at different sowing times in the climate of Diyarbakir, Turkey on biodiesel production, on engine performance and on emission values. The study was conducted in the trial areas of the Department of Field Crops of the Dicle University Faculty of Agriculture, in which the quality traits of the rapeseed (oil ratio and fatty acid content) were analyzed. The genotypes, 'Licord' was achieved the highest oil content (38.13%). The highest alpha-linolenic acid (1.25%), and oleic acid (65.1%) were recorded from the genotype 'Express'. The highest linoleic acid (18.16%) was achieved from Lirown genotype. Among the different varieties of rapeseed, those with the highest oil ratio and fatty acid content were selected and subjected to transesterification to obtain rapeseed oil methyl and ethyl esters. These were then tested in a small power diesel engine in accordance with the EN 14214 standard, which is considered applicable by the Energy Market Regulatory Board of Turkey for the investigation of the performance and emission characteristics of such ester fuels. The study made use of single-cylinder, direct injection, four-cycle, 5.5 kW nominal power diesel engine. The use of fatty acid esters was found to give moment and power values close to those of diesel engine fuel, although the ester fuels showed a slight increase in fuel consumption values. The transesterification of rapeseed was found to reduce viscosity and to decrease calorific value and specific weights. Emission values for CO and CO2 were found to be lower than number 2-D diesel fuel, while an increase was observed in the level of NON.

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