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    Prepubertal Unilateral Gynecomastia: Report of 2 Cases
    (Galenos Yayincilik, 2014) Demirbilek, Huseyin; Bacak, Gokhan; Baran, Riza Taner; Avci, Yahya; Baran, Ahmet; Keles, Aysenur; Ozbek, Mehmet Nuri
    Prepubertal unilateral gynecomastia is an extremely rare condition. At present, its etiology and management strategy are not well known. Two unrelated prepubertal boys of ages 8 and 9 who presented with complaints of unilateral enlargement of breast tissue are reported. Physical examination, biochemical, hormonal and oncologic work-up findings were normal. Both patients were treated with peripheral liposuction successfully. Histopathological and immunohistochemical examinations showed benign fibroglandular gynecomastia and intensive (3+) estrogen receptor expression in 100% of periductal epithelial cells. Although an extremely rare and generally benign condition, patients with prepubertal unilateral gynecomastia should have a full endocrine and oncologic work-up.