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    Co-existince of sickle cell disease and hemidiaphragm paralysis
    (Turkish Assoc Tuberculosis & Thorax, 2006) Babayigit, Cenk; Melek, Ismet Murat; Duman, Taskin; Senyigit, Abdurrahman; Gali, Edip
    Sickle cell anemia is a disease caused by production of abnormal hemoglobin. Infection, acute splenic sequestration crisis, aplastic crises, acute chest syndrome, stroke, cholelithiasis, renal disease and pain are the major complications. Unilateral or bilateral diaphragm paralysis maybe seen following phrenic nerve injury and with a variety of motor-neuron diseases, myelopathies, neuropathies, and myopathies. Prominent right hemi-diaphragma elevation was observed on chest radiograph of a 14 years' old female patient with sickle cell disease. Her medical history yielded neither trauma nor intra-thorasic surgery. She didn't have either motor deficit or sensation disorder on any region of her body. Thorax CT yielded no lession except the significantly elevated right diaphragma. Her cranial CT showed no lesion, too. Diagnosis of right hemidiaphragm paralysis was confirmed by positive Hitzenberg Sniff test on fluoroscopy. Although several pathophysiologic mechanisms are known to be involved and lead to central neurologic complications in sickle cell disease, involvement of peripheric nerves have not been reported. Here we present a 14 years' old female patient with sickle cell anemia and unilateral diaphragm paralysis, co-existince of which have not been reported so far.
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    Environmental malignant pleural mesothelioma in Southeast Turkey
    (Saudi Med J, 2006) Tanrikulu, Abdullah C.; Senyigit, Abdulrahman; Dagli, Canan E.; Babayigit, Cenk; Abakay, Abdurrahman
    [Abstract Not Available]
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    Pulmonary Alveolar Microlithiasis: Radiologic Findings of Eight Cases in Turkey
    (Ortadogu Ad Pres & Publ Co, 2010) Tanrikulu, A. Cetin; Dagli, Canan Eren; Senyigit, Abdurrahman; Nazaroglu, Hasan; Babayigit, Cenk
    Objective: Pulmonary alveolar microlithiasis (PAM) is a rare idiopathic disease characterized by presence of diffuse innumerable minute calculi called microliths The aim of this report was to describe the radiographic findings of PAM with particular attention to features provided by chest X-ray and high resolution computerized tomography (HRCT). Material and Methods: We diagnosed three index cases of PAM who came from the same village in 1996. In 2005 we performed a study including 279 residents of that village by using microfilm screening to determine undiagnosed cases. Five additional cases of PAM were detected and underwent HRCT. HRCT and chest X-ray images of eight cases were assessed specifically for patterns, distribution, and profusion of pulmonary abnormalities. Results: Of eight cases, four were adults and four were children. Diffuse typical microcalcifications were detected in chest X-ray in three cases while reticulonodular pattern was seen in three cases and reticular pattern in two cases. Fine microcalcification, parenchymal band and fisssural prominence were the most common findings on HRCT. Small subpleural cysts were detected in five cases but only case 1 showed black pleural line in chest X-ray. One case had small subpleural bullae and bronchiectatic changes in both lower lobes predominantly in the left lung in HRCT. Conclusion: Relatives of a patient with PAM having reticular or reticulonodular pattern in chest X-ray must be investigated in detail for PAM because it can be the early stage of the disease. HRCT has a major importance for the detection of the rapid progression.