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Öğe Absolute white blood cell count and neutrophil-lymphocyte ratio may predict the need for double- J stent Insertion in ureteral stones in children: A comparative study(2023) Önen, Abdurrahman; Aydoğdu, Bahattin; Okur, Mehmet Hanifi; Karabel, Musemma; Arslan, Serkan; Azizoğlu, Mustafa; Kamcı, Tahsin OnatObjective: Our goal was to determine whether or not a double-J (DJ) stent insertion is required in cases of ureteral stones based on the absolute white blood cell (WBC) counts, neutrophil-lymphocyte ratio (NLR), absolute monocyte counts, and other laboratory markers. Materials and Methods: The patients were divided into two groups as those who did (Group 1), and did not (Group 2) need DJ stent insertion. The age, symptoms, diagnosis, hemogram parameters, and treatment results of the patients were evaluated. Results: Forty-nine percent (n=44) of the patients were female and 51% (n=46) were male. The groups did not differ in terms of age and gender (p>0.05). A higher incidence of hematuria was observed in Group 1 (p<0.05). WBC (p<0.05), NLR (p<0.05), and monocyte counts (p<0.05) were found to be higher in Group 1. In the ROC analysis; WBC and NLR were found to be two predictive markers for the need for DJ stent insertion. At a cut-off value of 12.6 x 109/L, WBC had 37% sensitivity, and 81% specificity (AUC: 0.67; 95% CI: 0.54-0.80), and at a cut-off value of 3.8, NLR had 65% sensitivity, and 76% specificity (AUC: 0.70; 95%CI: 0.57-0.82) in predicting the need for a DJ stent insertion. Reoperation was not required in any case. Conclusion: In cases of ureteral stones, the absolute WBC count and NLR may help determine the requirement (if any) for a DJ stent insertion.Öğe The beneficial effects of the transanastomotic feeding tube in the management of congenital duodenal obstruction: a meta-analysis(Mexican Acad Surgery, 2023) Arslan, Serkan; Azizoğlu, MustafaObjective: We aimed to assess the evidence on the efficacy and safety of transanastomotic feeding tubes (TAFTs) in neonates with congenital duodenal obstruction (CDO), we conducted a systematic review. Material and methods: Using the databases EMBASE, PubMed, and Cochrane, we carried out a thorough literature search up to 2022. Studies comparing TAFT + and TAFT -for CDO were included. We applied a random effect model. Results: 505 CDO patients who met the inclusion criteria were selected. The TAFT + group had a shorter time to reach full feeds (weighted mean difference [WMD]: -6.63, 95% confidence interval [CI]: -8.83 --4.43; p < 0.001) and had significantly less central venous catheter (CVC) insertion (I2 = 85%) (RR: 0.43, 95% CI: 0.19-1.00; p < 0.05). Fewer patients in the TAFT + group received parenteral nutrition (PN) (I2 = 78%) (RR: 0.43, 95% CI: 0.20-0.95; p < 0.05). There was no statistically significant difference in terms of the development of sepsis (I2 = 37%) (risk ratio [RR]: 1.35, 95% CI: 0.52-3.46; p > 0.05). No statistically significant difference was observed in terms of length of stay (I2 = 82%) (WMD: 2.22, 95% CI: -7.59-12.03; p > 0.05) and mortality (I2 = 0%) (RR: 0.55, 95% CI: 0.07-4.34; p > 0.05). Conclusions: The use of the transanastomotic tube resulted in early initiation of full feeding, less CVC insertion, and less need for PN.Öğe Challenges in strategies for Amyand hernia in children: literature review with clinical illustrations(Springer Science and Business Media Deutschland GmbH, 2023) Klyuev, Sergey; Azizoğlu, MustafaIntroduction: Amyand hernia (AH) is a rare disease, so there are no standard strategies and there are many different aspects at each stage of its management. Based on our own experience, we encountered these differences even in a small number of cases and therefore sought to review the literature to highlight the diversity of approaches to this pathology. This review of the literature was not intended to describe the statistical findings found in the clinical case series, but rather to highlight the clinical and surgical difficulties of AH in children. Nevertheless, we conducted an introductory statistical study based on data from PubMed and Google Scholar to understand the global prevalence of AH. Materials and methods: The search for the key terms Amyand hernia, Amyand’s hernia, and “children” between 2003 and 2023 resulted in 52 PubMed and 548 Google Scholar articles. Results: After the exclusion of irrelevant studies, 101 articles were found. A total of 83 case reports describing 182 pediatric patients were used to understand the demographic distribution of this pathology. Given the impossibility of further comprehensive statistical analysis (due to heterogeneous data), a narrative design was used to describe the remaining aspects of AH management. Finally, three clinical cases demonstrated the mentioned aspects. Discussion: As a result of the search, conclusions were drawn about the main difficulties in the management of AH in children, which were discussed.Öğe Commentary on “Laparoscopic inguinal hernia repair (LIHR): the benefit of the double stitch in the largest single-center experience”(Springer Science and Business Media Deutschland GmbH, 2024) Azizoğlu, Mustafa; Okur, Mehmet HanifiWe have read with interest the study of Haveliwala et al. titled “Laparoscopic inguinal hernia repair (LIHR): the beneft of the double stitch in the largest single-center experience”, in which they published their inguinal hernia experiences at Great Ormond Street Hospital.Öğe Comparison of single-incision laparoscopic percutaneous and cystoscope forceps assisted morgagni hernia repair techniques(W.B. Saunders, 2024) Okur, Mehmet Hanifi; Aydoğdu, Bahattin; Azizoğlu, Mustafa; Arslan, Serkan; Bayram, Salih; Basuguy, Erol; 0000-0002-9217-423X; 0000-0002-6720-1515; 0000-0003-2858-3984; 0000-0002-3456-9217; 0000-0002-4360-6892Objective: Our goal was to compare single-incision laparoscopic percutaneous and cystoscope forceps-assisted Morgagni hernia repair techniques. Materials and methods: A total of 40 patients were allocated to two groups, each with 20 patients. Group 1: Single incision (port) laparoscopic surgical percutaneous Morgagni hernia repair (with a 5 mm Storz laparoscopic scope entered through the umbilicus). Group 2: Single incision (port) laparoscopic surgical percutaneous Morgagni hernia repair (with an 11 Fr [3.6 mm] cystoscope entered through the umbilicus + using forceps + sac plication, and sac cauterization). In Group 1; the sac was not removed. In group 2; we advanced the forceps through the cystoscope, caught the sac, pushed the needle through the sac, plicated the sac, and then cauterized the sac with Bugbee electrode. Results: Of the 40 patients, 70 % (n = 28) were male. The symptoms at admission included repeated chest infections (40 %), dyspnea (30 %), vomiting (22 %), and abdominal pain (22 %). No difference was found between groups in terms of age, gender symptomatology, or associated anomalies. The operation time was shorter in group 2 compared to group 1 (p < 0.05; 25 min vs 40 min). Although there was one recurrence in Group 1, no recurrence was reported in Group 2. The recurrence incidence did not differ between groups (p > 0.05). Conclusions: Cystoscope-assisted repair of Morgagni hernia was found to be superior in terms of safety and shorter operation time. Level of evidence: Type III. Type of the study: Retrospective study.Öğe Crystallized phenol for treatment of pilonidal sinus disease in children: a comparative clinical study(Springer, 2021) Arslan, Serkan; Okur, Mehmet Hanifi; Basuguy, Erol; Aydoğdu, Bahattin; Zeytun, Hikmet; Çal, Suat; Teğin, Serdest; Azizoğlu, MustafaBackground The aim of this study was to present our experience in the use of crystallized phenol (CP) to treat pediatric patients with 'simple' and complex' Pilonidal sinus disease (PSD). Materials and methods Patients who underwent CP treatment in between January 2015 and January 2020 were evaluated retrospectively, using prospectively collected data. The patients were divided into simple and complicated groups. The groups were assigned depending on the number of sinuses and clinical presentation. The groups were compared in terms of age, sex, number of sessions, cost analysis, body mass index (BMI), recurrence, time resolution, cosmetic results, results /improvement, and complications. Results This study included 54 patients: 28 (52%) girls and 26 (48%) boys. The mean number of sinuses was 2.4. Symptoms included discharge in 50 (92%) patients, and pain in 42 (78%) patients. Fifty (93%) patients experienced mild pain during the procedure, whereas four (7%) patients had moderate pain. The mean number of CP sessions was 2.9; mean numbers of CP sessions were 2.2 and 4.2 in the Simple and Complicated groups. In total, 5 of 54 patients (9%) had recurrence.At the end of treatment, therapeutic success was achieved in 49 of 54 (91%) patients: 31 of 33 (94%) patients in the Simple group and 18 of 21 patients (86%) in the complicated group. The mean treatment cost for the whole cohort was $17.40. One patient (2%) presented with moderate skin burns. Cosmesis was deemed acceptable by patients, although there was evidence of minor skin burns following the procedure. Conclusions The findings showed that the CP procedure was advantageous for treatment of PSD, because it was minimally invasive, cost-effective, provided good cosmesis, and had a high success rate and low complication rate. Furthermore, it did not require prior examination, and could be performed under local anesthesia. Therefore, the CP procedure may be useful as a first-line treatment option in children with PSDÖğe Effectiveness of extracorporeal shock wave lithotripsy in urolithiasis patients under 2 years of age(Permanyer Publications, 2023) Basuguy, Erol; Önen, Abdurrahman; Azizoğlu, Mustafa; Okur, Mehmet Hanifi; Aydoğdu, Bahattin; Arslan, SerkanObjective: In this study, we present our extracorporeal shock wave lithotripsy (ESWL) outcomes in urolithiasis patients under the age of two. Materials and Methods: The procedure was performed with patients < 2 years of age sedated, under anesthesia using ketamine and Dormicum (midazolam), in the supine position. Fragmentation was evaluated by fluoroscopy after the procedure. Results: A total of 74 procedures were performed on 65 kidneys. One patient with bilateral stones had two sessions of ESWL on the right side; three sessions of ESWL were performed in one patient with a unilateral stone, and two sessions were performed in seven patients with unilateral stones. All other patients underwent one session of ESWL. As post-procedural complications, hematuria was observed in 14 patients (12 mild and 2 significant), and vomiting occurred in 1 patient. Ureterorenoscopy was performed in 5 patients, and percutaneous nephrolithotomy in 6 patients due to a failed procedure. Conclusion: As a result, ESWL treatment is effective and has advantages such as a short hospitalization time, good reproducibility, cost-effectiveness, and a low rate of complications. Therefore, we recommend ESWL as the first-line treatment for renal and proximal ureteral stones in infants < 2 years of age.Öğe Fewer knots in circumcision are associated with less postoperative pain: A retrospective comparative study(Bukovyna State Medical University, 2023) Sağır, Süleyman; Azizoğlu, Mustafa; Ergün, MüslümMale circumcision is the most frequently performed surgical procedure among Muslim and Jewish communities, mainly for medical, religious, and traditional reasons (1-4). In the USA, circumcision is frequently performed for cosmetic purposes. Although it is seen as a simple procedure, it is quite prone to complications like other surgical procedures. The early and long-term complications of circumcision are well known and the overall complication rate has been reported between 0.2% and 3.9%. Common complications associated with circumcision are acute bleeding, pain, edema, wound infection, and unnecessary foreskin. Rare complications include meatal stenosis, urethral fistula, partial and total glandular amputations, glandular necrosis, penile curvature, and penile rotation. In addition, keloid formation and scar hypertrophy are some rare complications that cause poor cosmetic appearance.The aim of paper: Our aim in this study was to investigate the effect of the number of sutures placed during circumcision on postoperative pain, infection, bleeding amount, and analgesic need in children.Materials and methods: A total of 715 patients who applied to our hospital for circumcision requests between November 2019 and January 2022 were retrospectively analyzed. The patients were randomly divided into three groups according to the number of knots used during the surgical procedure: Group 1 (8 sutures), group 2 (6 sutures), and group 3 (4 sutures). The patients were evaluated in terms of whether they needed analgesics in the postoperative period (1-hour), bleeding status, and whether this bleeding needed re-intervention.Results: The average age of the participants in the study was 4.06±2.51 years, and the average weight was 18.66±7.07 kg. The operation was completed using 8 sutures (group 1) in 47.5%, 6 sutures (group 2) in 27.7%, and 4 sutures (group 3) in 24.9% of the patients. Postoperative infection developed in 2.8% of the participants, and bleeding was observed in 25.1%. The number of participants who needed analgesia for the first hour after the operation was 66.8%. The median value of the postoperative pain scale was 5 (range: 1-9), and those with a pain scale of 5-9 were 65.5%. There was no significant difference between the groups in terms of age, weight, development of infection, and bleeding (p>0.05). Analgesia was needed in 88.7% of those in group 1, 69.9% of those in group 2, and 21.6% of those in group 3 (p<0.001). A score (MPOS) of 5 or higher was found in 86.8% of those in group 1, 71% of those in group 2, and 18.6% of those in group 3 (p<0.001).Conclusions: our study showed that group 3 (4 sutures) achieved lower pain scores, less analgesic consumption, and lower agitation scores after circumcision compared to other groups.Öğe Letter to the editor in response to: Laparoscopic repair of morgagni hernia in children(W.B. Saunders, 2023) Okur, Mehmet Hanifi; Azizoğlu, MustafaDear Editor, We have read the “Laparoscopic Repair of Morgagni Hernia in Children” article with interest [1]. First, the authors mentioned in the operative technique section “two, 5 mm working ports were inserted on the lateral edges of rectus muscles from the right and left upper quadrants bilaterally.” However, in the picture given in Figure 1, an additional port was entered only on the left side, not on the right side. According to the picture given, sutures have already been placed on the diaphragmatic rims and are about to be attached. We think the statement that all operations were performed with the same surgical technique is unclear. It is confusing whether only one port or two ports are used.Öğe The value of hematological inflammatory parameters in the differential diagnosis of testicular torsion and epididymo-orchitis in children(2023) Arslan, Serkan; Azizoğlu, Mustafa; Kamçı, Tahsin Onat; Aydoğdu, Bahattin; Okur, M.Hanifi; Basuguy, Erol; Önen, AbdurrahmanAim: To investigate the value of neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) in differentiating acute scrotal conditions. Methods: A total of 60 patients, including 30 epididymo-orchitis and 30 testicular torsions, diagnosed and treated in our clinic between January 1, 2010 and December 2022, were included in the study. The patients were divided into two groups; group 1 (testicular torsion = TT) and Group 2 (epididymo-orchitis = EO). The age, diagnosis, and hemogram parameters of the patients were evaluated. Results: Both Group 1 and Group 2 consisted of 30 patients each. The mean ages of group 1 and 2 were 13.7, and 11.2 years, respectively (p>0.05). When compared to the group 2, NLR was higher in the group 2 (p<0.05). There was no statistically significant difference between the groups in terms of PLR value (p >0.05). ROC analysis was performed for NLR. According to the ROC analysis; at a cut-off value of 2.92, the sensitivity was 51% and the specificity was 87%, AUC (0.79; CI: 0.694 - 0.896). Conclusion: TT and EO can be diagnosed using inflammatory markers such as NLR. However, additional prospective studies are needed.