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    Effects of Intragastric Balloon on Body Mass Index, Lipid Profile and Blood Glucose Regulation: A Prospective Study
    (Dicle Üniversitesi, 2016) Erdem, Hasan; Aziret, Mehmet; Çetinkünar, Süleyman; Aktimur, Recep; Özdaş, Sabri; Yürekli, Banu; Yetişir, Fahri
    Objective: Obesity remains an increasing public health and socioeconomic problem. Life style changes including healthy diet and physical activity are the first-line therapy for successful weight loss. The intragastric balloon has been considered as an effective and reversible, non-surgical method for weight loss. In this study, we aimed to investigate the effects of Intragastric balloon on weight loss, lipid profiles and blood glucose regulation in obese patients Methods: 75 consecutive Intragastric balloon patients (55 Female, 20 Male) with a mean age of 35.2±9.6 years were included in this study. The study was conducted prospectively and an air-filled intragastric balloon was introduced in ambulatory settings. In this study, patients’ pre-intervention body mass index, peripheral blood parameters such as HbA1c, lipid profiles were recorded and compared with post-intervention values. Results: The median intervention time for intragastric balloon application was 13 min (8-19). After follow-up period of median 186 days (180-211), BMI was reduced significantly, 41.6±6.7 vs. 34.9±6.4 kg/m2 (p<0.001). The median excess weight loss was found to be 33.2% (14- 81.1). There is no statistically significant difference between pre-intervention and post-intervention valuables in terms of low-density lipoprotein, high-density lipoprotein, cholesterol and triglycerides levels (p>0.05). On the other hand, only pre and post-intervention HbA1c level was to be statistically significant (p=0.001) Conclusion: There was significant change in BMI and HbA1c level with the intervention of intragastric balloon after follow-up period. For long-term benefit of balloon, further studies are needed.