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Öğe The antimicrobial activity of essential oils of Hypericum scabrum, Hypericum scabroides and Hypericum triquetrifolium(Wiley, 2004) Kızıl, Göksel; Toker, Zuhal; Özen, Hasan Çetin; Aytekin, ÇetinThe essential oils of Hypericum scabrum, Hypericum scabroides and Hypericum triquetrifolium were studied for the first time for their antimicrobial activity against nine organisms. All the essential oils exhibited some broad spectrum antibacterial activity, at a concentration of 80 mug/mL. The essential oils of Hypericum species showed antibacterial activity against the tested organisms and a yeast. Copyright (C) 2004 John Wiley Sons, Ltd.Öğe Immobilization of ?-amylase via adsorption onto bentonite/chitosan composite: Determination of equilibrium, kinetics and thermodynamic parameters(Wiley-V C H Verlag Gmbh, 2014) Baysal, Zübeyde; Bulut, Yasemin; Yavuz, Murat; Aytekin, ÇetinImmobilization of -amylase onto bentonite/chitosan (BC) composite was studied via adsorption. The composite was characterized by FTIR, SEM, and surface area measurements. The effect of different factors such as, pH, temperature, initial enzyme concentration, and various thermodynamic parameters was determined. The maximum -amylase adsorption capacity of the BC composite was determined as 64mg/g at 0.8mg/mL enzyme concentration. The activity of the immobilized enzyme was measured under varying experimental conditions. The highest enzyme activity for free and immobilized enzyme was determined at 30 and 35 degrees C in 0.1M phosphate buffer at pH 7.0. The effect of substrate concentration on enzyme activity of free and immobilized enzymes showed a good fit to the Lineweaver-Burk plots. Michaelis constant, K-m, for the immobilized -amylase was found to be higher than for the free enzyme. The adsorption isotherm was modeled by the Langmuir equation.Öğe Proflavin içeren, (+)-Duocarmycin antibiyotiği analoglarının sentezlenmesi ve DNA üzerine etkilerinin araştırılması(2013) Kızıl, Murat; Tanrıkurt, Emen; Aytekin, Çetin; Kocakaya, Şafak Özhan; Çeken, Bircan Toprancı; Pirinççioğlu, Mihdiye[Abstract Not Available]
