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    Effects of eradication on proteinuria: a prospective study
    (Springer Wien, 2012) Aydogan, Timucin; Ulas, Turgay; Selcoki, Yusuf; Alkan, Rabia; Yilmaz, Omer Caglar; Yalcin, Kadir Serkan; Inan, Osman
    Background Helicobacter pylori ( H. pylori) is one of the most common bacterial infections, seen in humans worldwide and its possible relationship to different diseases is a focus of attention nowadays. The aim of this study was to analyse the effects of eradication on proteinuria. Ninety-nine patients suffering from dyspeptic complaints were recruited in this prospective study. The patients were divided into two groups according to the presence of infection. Thus, a total of 67 positive and 32 negative patients were studied. The positive patients' group was divided into two groups according to response to eradication treatment. A total of three groups were formed, viz; group 1 comprises of patients who are positive and responds positively to eradication therapy, group 2 comprises of patients who are positive and responds negatively to eradication therapy and group 3 is the control group and comprises of patients that are negative. Urine samples to obtain the protein/creatinine ratio were collected initially and at the end of the study from all patients. Mean difference levels (pre- and post-treatment difference) of urine protein/creatinine ratio was 0.055 +/- 0.13 in group 1. The ratio was -aEuro parts per thousand 0.0007 +/- 0.0067 in group 2 and -aEuro parts per thousand 0.0022 +/- 0.008 in group 3. A statistically significant difference was found in group 1 compared to the other groups in terms of mean difference levels of protein/creatinine ratios (p < 0.001). As a result of our study, treatment of eradication significantly reduced the proteinuria within the normal limits.
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    Evaluation of sleeping energy expenditure using the SenseWear Armband in patients with overt and subclinical hypothyroidism
    (Canadian Soc Clinical Investigation, 2012) Ulas, Turgay; Buyukhatipoglu, Hakan; Eren, Mehmet A.; Dal, Mehmet S.; Torun, Aysenur; Aydogan, Timucin; Demir, Mehmet E.
    Purpose: The aim of the present study was to evaluate the average sleeping energy expenditure (EE) levels using the SenseWear Armband (SWA) in patients with overt and subclinical hypothyroidism. Methods: Sixty patients with hypothyroidism and 30 healthy individuals were recruited for the study. Hypothyroid patients were divided into two groups: group 1 (n = 30) consisted of patients with overt hypothyroidism and group 2 (n = 30) consisted of patients with subclinical hypothyroidism. Lastly, group 3 (n = 30) consisted of healthy subjects. The average EE and metabolic equivalent of task (MET) values during sleep of all the hypothyroid participants were analyzed at baseline and at the end of the study. Data were also obtained from the healthy subjects at baseline. Results: The average sleeping EE and METs values were not significantly different at baseline. Similarly, these values did not change significantly after achieving a euthyroid state via thyroid hormone replacement (both p > 0.05). Conclusions: Contrary to what has been previously reported, the average sleeping EE and METs values in all hypothyroid patients and healthy individuals were similar at baseline and did not change in the patients with overt and subclinical hypothyroidism after achievement of a euthyroid state.