Yazar "Aydin, Seniz Ongoren" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • [ X ]
    Öğe
    Acute colitis presenting with hematochezia in a patient with chronic myeloid leukemia during dasatinib therapy
    (Aves, 2014) Eskazan, Ahmet Emre; Hatemi, Ibrahim; Aydin, Seniz Ongoren; Ar, Muhlis Cem; Soysal, Teoman
    [Abstract Not Available]
  • [ X ]
    Öğe
    The Association Between JAK2V617F Mutation and Bone Marrow Fibrosis at Diagnosis in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms
    (Galenos Yayincilik, 2012) Ar, M. Cem; Buyuktas, Deram; Eskazan, A. Emre; Aydin, Seniz Ongoren; Tanrikulu, Eda; Baslar, Zafer; Buyru, A. Nur
    Objective: Bone marrow fibrosis is the second most common complication that causes morbidity and mortality in patients with Philadelphia-negative myeloproliferative neoplasms (MPNs). The aim of this study was to investigate the association between JAK2V617F mutation and bone marrow fibrosis at diagnosis in patients with MPNs. Material and Methods: In total, 149 patients with MPNs were retrospectively evaluated to determine if there was an association between the histological grade of bone marrow fibrosis and JAK2V617F mutation. Results: In all, 67.7% of the patients carried the mutated JAK2 gene. The presence of JAK2V617F mutation was not associated with the occurrence of bone marrow fibrosis (P = 0.55) or its grade at diagnosis (P = 0.65). Conclusion: Molecular mechanisms or genetic defects other than JAK2V617F may underlie the occurrence of bone marrow fibrosis in patients with MPNs.
  • [ X ]
    Öğe
    Successful Management of Chronic Refractory Immune Thrombocytopenia with Laparoscopic Splenectomy in a Patient with Acute Promyelocytic Leukemia
    (Springer India, 2013) Eskazan, Ahmet Emre; Salihoglu, Ayse; Gulturk, Emine; Aydin, Seniz Ongoren; Tuzuner, Nukhet; Aydin, Yildiz
    Acute promyelocytic leukemia (APL) is a particular type of acute myeloid leukemia with characteristic biological and clinical features, the frequent association at diagnosis of a severe hemorrhagic diathesis. Immune thrombocytopenia (ITP) is a common autoimmune disease characterized by low platelet counts and an increased risk of bleeding. Here we present a patient with the diagnosis of APL who achieved and maintained a remission with an induction consisting of idarubicin and ATRA, and then developed corticosteroid refractory ITP which is successfully treated with laparoscopic splenectomy.