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    Acupuncture stimulation causes earlier increase in the size and blood flow of corpus luteum and progesterone levels in dairy cows
    (Wiley-Blackwell, 2015) Kucukaslan, I.; Aslan, S.; Ay, S. S.; Kaya, D.; Findik, M.; Kacar, C.; Wollgarten, B.
    [Abstract Not Available]
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    Öğe
    Beneficial effects of Beta-carotene injections prior to treatment with PGF2? on the fertility of postpartum dairy cows
    (Ecole Nationale Veterinaire Toulouse, 2012) Ay, S. S.; Kaya, D.; Kucukaslan, I.; Agaoglu, A. R.; Emre, B.; Handler, J.; Findik, M.
    This study examined the effects of Beta-carotene (beta C) injections before estrus synchronization with PGF(2)alpha on fertility parameters in cows. A total of 124 postpartum (pp) cows were used. In GI (n=25), beta C (Carofertin (R), 0.4 mg/kgBW, i.m.) was injected on d 15 and 45 pp. In GII (n=25), beta C was administered on d 15 pp. In GIII (n=25), beta C was administered on d 45 pp. In GIV (n=25), beta C was injected on d 35 and 45 pp. GV (n=24) was set aside as a control group. All animals received PGF(2)alpha (Iliren (R), 0.0015 mg/kgBW, i.m.) on d 50 and 61 pp. Blood samples were collected on d 15,48 and three days after each beta C injection. The overall pregnancy rate was determined to be higher in GI (100%) and GIV (88.0%) than GV (70.8%) (P<0.01). The number of services per conception was the lowest in GI (1.4) and GII (1.4), while days of first service were lower in GIII (90.3 d) and GIV (90.8 d) (P<0.05). The insemination index was found to be lowest in GI (1.4). These results suggest that two administrations of beta C in the early and late pp period before administering PGF(2)alpha can improve fertility. It was concluded that when serum beta C concentrations remain high for a long time (30d) as a results of beta C injections, fertility can be improved.
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    Öğe
    The effect of acupuncture application during diestrus periods on the size and blood flow of corpus luteum and hormonal parameters in dairy cows
    (Wiley-Blackwell, 2014) Kucukaslan, I.; Ay, S. S.; Kaya, D.; Findik, M.; Aslan, S.
    [Abstract Not Available]
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    Öğe
    The effectiveness of combined preventive treatment with Ceftiofur, Oxytocin and PGF2? on fertility parameters in cows
    (Ecole Nationale Veterinaire Toulouse, 2012) Kaya, D.; Ay, S. S.; Kucukaslan, I.; Beceriklisoy, H. B.; Agaoglu, A. R.; Findik, M.; Ozyurtlu, N.
    The present study is aimed at evaluating the effectiveness of combined preventive treatment with Ceftiofur Hydrochloride (CHR), Oxytocin (OXT) and PGF(2 alpha) on fertility parameters and puerperal disorder rates in postpartum (pp) dairy cows. A total of 191 Holstein-Friesian cows were divided into four groups. The cows in group I (GI; n=37) and II (GII; n=69) were treated on a daily basis with CHR and OXT for five and three days pp, respectively. Group III (GIII; n=52) was designed as the PGF(2 alpha) group, and group IV (GIV; n=33) served as a control group. The animals in GI, GII, and Gill were given a PGF(2 alpha) analogue on days 15 and 26 pp. Each group was further divided into subgroups of normal parturition (np) and dystocia (d) when the study results were evaluated. It was found that the first service pregnancy rates for the subgroup of dystocia were significantly higher (P<0.05 and P<0.01) in subgroup GII (76.9%) than in GI (30.0%) and GIV (37.5%). Furthermore, the median time to first service and the median time to pregnancy were longer for cows in subgroup GIVd as compared with subgroups GId, GIId, and GIIId (P<0.001; P<0.01). Group II was found to have the lowest endometritis rates after treatment of subgroups-d and -np. No statistically significant difference was found between the groups with regard to cystic ovary rates after treatment (P>0.05). As the treatment with CHR-OXT combined with PGF(2 alpha) on days 15 and 26 was associated to improved uterine involution patterns and reproductive performance, our results suggest that administration of this preventive treatment would be useful, especially for cases of dystocia.
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    The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches
    (Elsevier Science Bv, 2014) Kaya, D.; Kucukaslan, I.; Agaoglu, A. R.; Ay, S. S.; Schaefer-Somi, S.; Emre, B.; Bal, Y.
    This study was designed to assess endocrine changes associated with termination of midterm pregnancy after use of two different protocols. For this purpose we compared the effects of aglepristone (AGL) alone and in combination with cloprostenol (CLO) on serum concentrations of progesterone (P-4), estradiol (E-2) and relaxin (RLN) measured at shortterm intervals during the abortion period in bitches. Fourteen pregnant bitches between day 25 and 32 of gestation were used in the study. In the AGL group (n = 7), aglepristone was administered solely (10 mg/kg body weight (BW), subcutaneously, once daily on two consecutive days) whereas in the AGL-CLO group (n = 7), aglepristone (dosage as in AGL group) and cloprostenol (1 mu g/kg BW, subcutaneously, same with aglepristone) were combined. All pregnancies were successfully terminated 5.2 1.6 days after initiation of treatments, which was significant in both groups (P> 0.05). At the time of the start of abortion (SA) and the end of abortion (EA), the mean P4 concentrations were 26.6 7.3 and 12.0 6.4 ng/ml in AGL group, and 2.7 0.7 and 0.9 0.1 ng/ml, in AGL-CLO group, respectively (P< 0.01). Serum E-2 concentrations were significantly higher (P< 0.05) in AGL group at 42, 48, 54 hand SA after initiation of treatment. In the AGL-CLO group, serum RLN concentrations did not significantly change from the initiation of treatment to EA (P> 0.05). However, markedly higher RLN concentrations (P< 0.05) were observed in the AGL group at 48 h (1.5 0.7 ng/ml) and at SA (1.6 0.5 ng/ml). The results of the present study indicate that changes in the hormonal concentrations affect the mechanism of abortion in different ways. Further in depth studies investigating changes in the expression of hormone receptors inside the ovary, endometrium and placenta might be helpful to our understanding of the endocrinological differences observed in this study. (C) 2014 Elsevier B.V. All rights reserved.