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Öğe Ağır kifoskolyozlu hastada supin pozisyonda ultrasonografi eşliğinde perkütan nefrolitotripsi(2011) Bozkurt, Yaşar; Atar, Murat; Yıldırım, Kadir; Söylemez, Haluk; Kılıç, Fahrettin; Sancaktutar, Ahmet Ali; Penbegül, NecmettinPerkutaneus nefrolitotomi (PNL) böbrek taşlarının tedavisinde altın standart olarak kabul edilmektedir. Ancak anatomik anomalisi olan ve kas-iskelet sistemi deformitesi olan hastalarda anormal anatomiden dolayı uygulanması zor olabilir. Kifoskolyozis kas –iskelet sistemi hastalığı olup; böbrek ve etrafındaki organlar arasında anormal anatomik oluşumlar bulunabilir. Burada 38 yaşında ciddi kifoskolyozisi olan bir hastada supin pozisyonda ultrasonografi kılavuzluğunda PNL uyguladığımız vakayı sunduk.Öğe An Alternative and Inexpensive Percutaneous Access Needle in Pediatric Patients(Elsevier Science Inc, 2012) Penbegül, Necmettin; Soylemez, Haluk; Bozkurt, Yasar; Sancaktutar, Ahmet Ali; Bodakci, Mehmet Nuri; Hatipoglu, Namik Kemal; Atar, MuratINTRODUCTION The most important factor that increases the cost of percutaneous surgery is the disposable instruments used for the surgery. In this study we present the advantages of using an intravenous cannula instead of a percutaneous access needle for renal access. TECHNICAL CONSIDERATIONS Recently, percutaneous stone surgery has grown in use in pediatric cases and is considered a minimally invasive surgery. The most important step in this surgery is access to the renal collecting systems. Although fluoroscopy has been used frequently at this stage, the use of ultrasound has recently increased. During percutaneous accesses under all types of imaging techniques, disposable 11- to 15-cm-long 18-ga needles are used. In pediatric cases, these longer needles are difficult to use. Using disposable materials in percutaneous nephrolithotomy increases the cost of the procedure. Therefore, we asserted that percutaneous access especially in pediatric cases could be performed using a 16-ga intravenous cannula (angiocath). Indeed, percutaneous access was performed successfully, especially in pediatric preschool patients. Shorter needle length, easy skin entry, comfort of manipulation, clear visualization of the metal needle on ultrasound, and wide availability can be considered advantages of this method. The angiocath is also less expensive than a percutaneous access needle. CONCLUSION Angiocath is inexpensive, easily available, and practical, and it is the shortest needle to perform percutaneous access in pediatric patients. UROLOGY 80: 938-940, 2012. (C) 2012 Elsevier Inc.Öğe ANTIOXIDANT SIGNAL AND KIM-1 LEVELS IN ESWL INDUCED KIDNEY INJURY(Mary Ann Liebert, Inc, 2012) Hatipoglu, Namik Kemal; Evliyaoglu, Osman; Bodakci, Mehmet Nuri; Atar, Murat; Penbegül, Necmettin; Soylemez, Haluk; Sancaktutar, Ahmet Ali[Abstract Not Available]Öğe Askerlik çağındaki erkeklerde inguinal ve genital organ anomalisi sıklığı ve farkındalığı(2011) Bozkurt, Yaşar; Penbegül, Necmettin; Söylemez, Haluk; Atar, Murat; Sancaktutar, Ahmet AliAmaç: Eksternal genital anomalilerin erken tanı ve tedavisi gelecekteki fertilite potansiyelinin korunması açısından önemlidir. Bu kesitsel çalışmada genç Türk erkeklerinde inguinal ve genital anomali sıklığının, tedavi oranlarının ve bu konudaki toplum bilincinin belirlenmesi amaçlanmıştır. Gereç ve yöntem: İzmir’de askerliğini yapmakta olan 2,061 genç erkek çalışmaya alındı. Bütün askerler aynı ürolog tarafından özel bir odada muayene edildi ve inguinal ve genital anomalileri kaydedildi. Anomali tespit edilenlere aldıkları tedaviler, tedavi zamanları, tedavi sonuçları ve hastalıkları hakkındaki bilgileri soruldu. Bulgular: Katılımcıların yaş ortalaması 20.3±1.0 (dağılım 19-27) idi. Toplam 681 kişide (%33.0) 746 anomali tespit edildi. Sıklık sırasına göre tespit edilen anomaliler; varikosel (%24.2), mea darlığı (%4.0), penil kurvatur (%2.0), inguinal herni (%1.8), inmemiş testis (%1.8), hipospadias (%0.9), hidrosel (%0.7), atrofik testis (%0.4) ve retraktil testis (%0.4) idi. Katılımcılardan 18’i (%0.9) sünnet olmamıştı. Anomalili hastalardan sadece 35’i (%4.7) opere olmuştu. Yapılan ameliyatlar; varikoselektomi, orşiopeksi, orşektomi, inguinal herni onarımı ve hipospadias onarımı idi. Sonuç: İnguinal ve genital sistem anomalileri genç Türk erkeklerinde yaygın olarak görülmektedir. Buna karşın ülkemizde bu konudaki toplum bilinci yeterli değildir ve bu anomaliler zamanında tedavi edilmemektedir.Öğe Association Between Neuropathic Pain, Pregabalin Treatment, and Erectile Dysfunction(Wiley-Blackwell, 2014) Bozkurt, Mehtap; Gocmez, Cuneyt; Soylemez, Haluk; Daggulli, Mansur; Em, Serda; Yildiz, Mehmet; Atar, MuratIntroduction. The pathophysiology of erectile dysfunction (ED) may be vasculogenic, hormonal, anatomical, neurogenic, drug-induced and/or psychogenic in origin. Neuropathic pain (NP) may facilitate ED, because it is frequently associated with anxiety, depression, and its drug, pregabalin, may also contribute ED. Aim. The objective of this study was to determine whether pregabalin treatment for patients with neuropathic pain promotes erectile dysfunction. Methods. The study sample consisted of a total of 102 male subjects that were subdivided into three groups. Group 1 patients (n = 31) had a pre-existing diagnosis of NP and was treated with 300 mg/day of pregabalin for at least 3 months. Group 2 patients (n = 34) were diagnosed with NP for at least 3 months; however, neither were they treated with pregabalin nor did they received physical therapy throughout the study. Lastly, healthy age-matched control subjects comprised group 3 (n = 37). Main Outcome Measures. Patients in all groups completed the International Index for Erectile Function (IIEF) questionnaire. Results. Mean age and mean body mass index did not differ significantly between each of the three groups. The cause of NP and the mean duration of having a diagnosis of NP did not differ significantly in groups 1 and 2. However, IIEF scores were significantly lower for group 1 when compared to group 2 in terms of erectile function, orgasmic function, overall satisfaction and total score. Yet groups 1 and 2 did not diverge significantly in the intercourse satisfaction and sexual desire scores. Overall IIEF scores for group 3 were significantly higher than those of group 2 except for mean erectile function scores. Conclusion. Taking pregabalin for the treatment of neuropathic pain poses an increased risk for developing ED in male patients. Thus, clinicians prescribing pregabalin to patients diagnosed with neuropathic pain should assess for ED before and during treatment with this medication.Öğe Association of microRNA-related gene polymorphisms and idiopathic azoospermia in a south-east Turkey population(Taylor & Francis Ltd, 2017) Ay, Ozlem Izci; Balkan, Mahmut; Erdal, Mehmet Emin; Rustemoglu, Aydin; Atar, Murat; Hatipoglu, Namik Kemal; Bodakci, Mehmet NuriMicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression. Although it is reported in many studies that there are associations between alterations of miRNA homeostasis and pathological conditions such as cancer, psychiatric and neurological diseases, cardiovascular disease and autoimmune disease, the effects of common genetic variants of these genes on male infertility are unclear. To better understand this effect, we performed a case-control study including a total of 108 infertile men with idiopathic azoospermia and 125 fertile control subjects. Real-time polymerase chain reaction was used to genotype six single-nucleotide polymorphisms (SNPs) of microRNA biogenesis pathway genes and the associations between individual and combined genotypes and idiopathic azoospermia were analysed. The results showed significant difference between the individual AA genotype frequency of the GEMIN3 (rs197388) gene in the patient and control groups, indicating that the AA genotype may be considered as indicative of a higher predisposition to idiopathic azoospermia. The combined genotype analysis, including six SNPs, revealed statistically significant differences between the patients and control subjects for some combinations. For example, the frequency of genotype distributions of the AA\CA-CC-TT-AT genotype combination for the XPO5-RAN-DICER1GEMIN3 combined loci was significantly different, and it may be considered a predisposition to idiopathic azoospermia. According to the obtained results, both individual and combined genotypes of SNPs from miRNA genes may be used to predict the risk of male infertility with idiopathic azoospermia.Öğe Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women with ureteral stones and hydronephrosis(Academic Journals, 2012) Atar, Murat; Bozkurt, Yasar; Sancaktutar, Ahmet Ali; Soylemez, Haluk; Penbegül, Necmettin; Sak, Muhammet Erdal; Tekin, RecepThe aim of this study is to identify bacterial agents and their antibiotic susceptibility patterns isolated from pregnant women with symptomatic ureterolithiasis. Seventeen patients who had proven ureteral stones, positive urine cultures and underwent intervention for ureterolithiasis treatment between January, 2008 to December, 2011 were included in this study. Bacteriuria was defined as accounts of 10(5) cfu/ml in urine culture. The mean age and gestational period was 24.5 years and 25.5 weeks. The major symptoms were renal colic, hematuria and fever-chills. The overall prevalence of urinary tract infection (UTI) in pregnancy with ureteral stones was 17/65 (26.2%). Escherichia coli are the most common etiological agent (64.7%), followed by Klebsiella and Staphylococcus. The rate of resistance of E. coli to amoxicillin-clavulanate, ampicilin, cefotaxime, ciprofloxacin, trimethoprim/sulfamethoxazol, ceftriaxone, piperacillin/ tazobactam and imipenem were 50, 45.5, 100, 18, 36.4, 28.6, 36.4, 0%, respectively. The rate of resistance of Klebsiella to Ampicilin were 80% and Amoxicillin-Clavulanate, Cefazolin, Cefepime, Ceftazidim were 60%. There were no resistance of Klebsiella to ciprofloxacin, gentamicin, meropenem and amikacin. Significant bacteriuria was observed in these patients and we recommend urine cultures in all pregnant women with ureteral stones during pregnancy. Ceftriaxone is recommended for the patients who have UTI with ureteral stones during pregnancy because of its high specificity and sensitivity.Öğe Caffeic Acid Phenethyl Ester Protects Kidneys against Acetylsalicylic Acid Toxicity in Rats(Taylor & Francis Ltd, 2012) Bozkurt, Yasar; Bozkurt, Mehtap; Turkcu, Gul; Sancaktutar, Ahmet Ali; Soylemez, Haluk; Penbegül, Necmettin; Atar, MuratAim: The aim of this study was to investigate the protective effect of caffeic acid phenethyl ester (CAPE) on acetylsalicylic acid (ASA)-induced renal damage in rats. Materials and methods: A total of 40 rats were randomly divided into five groups, with eight rats in each group-group 1: control, not receiving any medication; group 2: ASA (50 mg/kg/day); group 3: ASA (50 mg/kg/day) + CAPE (20 mu g/kg/day); group 4: ASA (100 mg/kg/day); and group 5: ASA (100 mg/kg/day) + CAPE (20 mu g/kg/day). ASA and CAPE were given via orogastric gavage for 5 days. The total oxidant status (TOS), total antioxidant capacity (TAC), and paraoxonase-1 (PON-1) activity of the blood samples and kidney tissues were determined. Histopathological examinations of the kidneys were performed using light microscopic methods. Results: The TOS level in the serum of rats and kidney tissues given ASA (groups 2 and 4) significantly increased, but the levels of TAC and PON-1 in these tissues significantly decreased in group 4 when compared with the control rats (p < 0.05). The levels of TAC and PON-1 in the kidney tissues increased and the levels of TOS decreased in the CAPE treatment groups (groups 3 and 5) when compared with the rats in the no CAPE treatment groups (groups 2 and 4). The PON-1, TAC, and TOS values reverted to normal levels in group 5 when compared to group 4 (p < 0.05). These results were supported by histopathological observation. Conclusion: Oxidative stress plays an important role in ASA-induced nephrotoxicity, and CAPE may protect against ASA-induced nephrotoxicity in rats.Öğe A case of a scrotal mesenteric cyst(Dicle Üniversitesi Tıp Fakültesi, 2014) Bodakçı, Mehmet Nuri; Hatipoğlu, Namık Kemal; Fırat, Uğur; Penbegül, Necmettin; Atar, MuratMesenteric cysts are rarely seen intraabdominal mass lesions which can manifest themselves with different clinical signs, and symptoms. They can locate in the mesenterium from duodenum down to rectum, and also in the retroperitoneal space. Herein we present a very rare case of a scrotal mesenteric cyst which resembled an epididymal cyst in a 6-year-old boy. Ultrasonographic examination revealed a multiloculated cyst completely filling the scrotal sac, and the cyst was excised surgically. Histopathological examination described the surgical specimen as chylolymphatic mesenteric cyst, and during one year follow-up any recurrence was not observed.Öğe A Cheap Minimally Painful and Widely Usable Alternative for Retrieving Ureteral Stents(Karger, 2011) Soylemez, Haluk; Sancaktutar, Ahmet Ali; Bozkurt, Yasar; Atar, Murat; Penbegül, Necmettin; Yildirim, KadirObjective: To describe a cheap, minimally painful and widely usable method for retrieving ureteral stents by using an ureteroscope. Subjects and Methods: Sixty-seven patients with ureteral stents were enrolled in this study. The patients were randomized into a cystoscopic (35 patients) and a ureteroscopic (32 patients) group. All stents were retrieved by a flexible cystoscope in the first group and by a ureteroscope in the second group under local anesthesia. Patients in each group were assessed for stented time, stent side, cause of stent placement, operative time, peroperative pain, postoperative pain, irritative voiding symptoms and hematuria. Also costs of instruments were calculated. Results: Stents were successfully retrieved in 67 patients. There were no statistical differences in the two groups regarding patient gender and age or stent side, operative time, stented time, mean operative pain score, irritative voiding symptom scores and hematuria. Total selling price was USD 20.399 for flexible instruments and USD 10.516 for rigid ones. Total maintenance price was higher in flexible instruments than in the rigid ones (USD 197.8 and 51.7 per use, respectively). Conclusion: Ureteroscopic stent retrieval is a minimally painful, safe and highly tolerable method under local anesthesia as well as flexible cystoscopic retrieval. Also, it is a cheap and widely usable method. Copyright (C) 2011 S. Karger AG, BaselÖğe Comparison of a 4.5 F semi-rigid ureteroscope with a 7.5 F rigid ureteroscope in the treatment of ureteral stones in preschool-age children(Springer, 2012) Atar, Murat; Sancaktutar, Ahmet Ali; Penbegül, Necmettin; Soylemez, Haluk; Bodakci, Mehmet Nuri; Hatipoglu, Namik Kemal; Bozkurt, YasarThe aim of this study was to compare the success and complication rates of a 4.5 F ureteroscope with a 7.5 F ureteroscope in the treatment of urolithiasis in preschool-age children. We retrospectively reviewed 69 ureteroscopy (URS) procedures in a pediatric population (40 boys, 29 girls). We divided the patients into two groups according to the type of ureteroscope used: group 1 (n = 42, Storz 7.5 F) and group 2 (n = 27, Wolf 4.5 F). We statistically compared all the procedures performed in both groups regarding patient age, complication rates, whether the procedure was therapeutic, and whether we used a guidewire. Additionally, in cases with ureteral stones, we also compared the stone clearance rate and the necessity of X-ray imaging between the two groups. The mean patient age was 56.04 months in group 1 and 47.48 months in group 2 (p = 0.057). The stone-free rate was 78.6 % in group 1 and 92.6 % in group 2 (p > 0.05). However, when we compared the stone-free rates for patients younger than 3 years, the rate was 66.7 % in group 1 and 93.8 % in group 2 (p < 0.05). The difference was not statistically significant for patients between the ages of 4 and 7 years. The success and failure rates revealed better outcomes for treatment of ureteral stones with a 4.5 F ureteroscope. We recommend the use of the mini-ureteroscope, especially in infants and preschool-age children.Öğe Comparison of Laparoscopic and Microscopic Subinguinal Varicocelectomy in terms of Postoperative Scrotal Pain(Soc Laparoendoscopic Surgeons, 2012) Soylemez, Haluk; Penbegül, Necmettin; Atar, Murat; Bozkurt, Yasar; Sancaktutar, Ahmet Ali; Altunoluk, BulentBackground and Objectives: In this study, 2 different varicocelectomy methods were compared with regard to postoperative scrotal pain, length of operation, and complications. Methods: Forty varicocele patients, who visited our clinic because of infertility or scrotal pain between 2008 and 2009, were enrolled in this clinical study. Microscopic subinguinal varicocelectomy was performed on 20 patients in Group I, and laparoscopic varicocelectomy was performed on 20 patients in Group II. Following surgery, the patients were assessed for postoperative requirements for analgesia; return to normal activity; varicocele recurrence; hydrocele formation; scrotal pain at postoperative days 1, 3, and 7; and other complications. Results: Mean age was 24.2 +/- 3.4 years in Group I and 25.1 +/- 12.1 years in Group II. Mean pain scores at postoperative 1, 3, and 7 days in Group I were (5.20 +/- 11.14, 4.60 +/- 10.97, and 3.50 +/- 0.97, respectively) significantly higher than those of Group 11 (0.70 +/- 0.82, 0.60 +/- 10.84, and 0.10 +/- 10.32, respectively). Time to return to normal activity was significantly shorter in Group 11 (3.7 +/- 2.1 days) compared with Group I (6.8 +/- 13.4 days) (p = 0.028). However, the number of recurrences and hydroceles, as a complication of varicocelectomy, was 2 times higher in Group II (10%) than in Group I (5%). Conclusions: We believe that laparoscopic varicocelectomy is a safe, effective, and minimally invasive procedure. Furthermore, reduced postoperative discomfort and earlier return to normal activity are additional advantages of this method.Öğe Comparison of pneumatic and laser lithotripsy in the treatment of pediatric ureteral stones(Elsevier Sci Ltd, 2013) Atar, Murat; Bodakci, Mehmet Nuri; Sancaktutar, Ahmet Ali; Penbegül, Necmettin; Soylemez, Haluk; Bozkurt, Yasar; Hatipoglu, Namik KemalObjective: To compare the effectiveness and safety of pneumatic and holmium: YAG laser lithotripters in the treatment of pediatric ureterolithiasis. Patients and methods: Medical records of patients treated using pneumatic (PL) (n = 29) or laser (LL) (n = 35) lithotripter between 2009 and 2011 were retrospectively analysed. The patients were evaluated with respect to age, gender, stone size, complications, and stone-free rates 1 month after the operation. Results: For the PL and LL groups, mean ages (8.8 +/- 3.4 and 8.3 +/- 3.5 years), male/ female ratios (19:10 and 22:13) and stone locations were similar (p > 0.05). Mean stone sizes were 55.6 mm(2) and 47.6 mm(2) in the PL and LL group, respectively, with no statistically significant difference (p = 0.850). Mean operative times were 20.5 min in the PL group and 25.2 min in the LL group, with a statistically significant difference (p = 0.020). Stone-free rates 1 month after intervention were 79% in the PL group and 97% in the LL group (p = 0.022). Stone migration was detected in the PL group (n = 6) and in the LL group (n = 1). No major complication was found in either group. Conclusion: In the ureteroscopic treatment of pediatric ureterolithiasis, both pneumatic and laser lithotripters are effective and successful. However, laser lithotripsy has a higher stone-free rate and lower complication rate. (C) 2012 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.Öğe Comparison of Shockwave Lithotripsy and Microperc for Treatment of Kidney Stones in Children(Mary Ann Liebert, Inc, 2013) Hatipoglu, Namik Kemal; Sancaktutar, Ahmet Ali; Tepeler, Abdulkadir; Bodakci, Mehmet Nuri; Penbegül, Necmettin; Atar, Murat; Bozkurt, YasarPurpose: We aimed to compare the outcomes of microperc and shockwave lithotripsy (SWL) for treatment of kidney stones in children. Patients and Methods: The medical records of 145 patients under the age of 15 years with opaque and single kidney stones treated with either SWL or microperc were retrospectively reviewed. Both groups were compared in terms of fluoroscopy and operative time, re-treatment, complications, success rate, and secondary and total number of procedures. Results: Microperc and SWL were performed on 37 and 108 pediatric patients, respectively. The mean age of the patients was 5.914.03 years (1-15) and 8.43 +/- 4.84 (1-15) years in the SWL and microperc groups, respectively (P=0.004). The mean stone size was 11.32 +/- 2.84 (5-20) mm in the SWL group and 14.78 +/- 5.39 (6-32) mm in the microperc group (P<0.001). In the SWL group, 31 (28.7%) patients underwent a second SWL session and 6 (5%) had a third session. Finally, 95 (88%) patients were stone free at the end of the SWL sessions. In the microperc group, the stone-free rate was 89.2% in a single session (P=0.645). The mean duration of hospitalization was 49.2 +/- 12.3 (16-64) hours in the microperc group and 8.4 +/- 2.3 (6-10) hours per one session in the SWL group (P<0.001). The fluoroscopy time was significantly longer in the microperc group compared with the SWL group (147.3 +/- 95.3 seconds vs 59.6 +/- 25.9 seconds, P<0.001). The rate of requirement for an auxiliary procedure was higher in the SWL group than in the microperc group. The overall complication rates for the microperc and SWL groups were 21.6% and 16.7%, respectively (P=0.498). Conclusions: The results of our study demonstrate that microperc provides a similar stone-free rate and a lower additional treatment rate compared with SWL in the treatment of kidney stone disease in children.Öğe Debate on monoplanar percutaneous nephrolithotomy(Springer, 2013) Hatipoglu, Namik Kemal; Bodakci, Mehmet Nuri; Penbegül, Necmettin; Bozkurt, Yasar; Sancaktutar, Ahmet Ali; Atar, Murat; Soylemez, Haluk[Abstract Not Available]Öğe Düşük prostat spesifik antijen değeri olan hastalara yapılan transrektal prostat biyopsi sonuçları(Dicle Üniversitesi Tıp Fakültesi, 2012) Bodakçi, Mehmet Nuri; Bozkurt, Yaşar; Atar, Murat; Hatipoğlu, Namık Kemal; Penbegül, Necmettin; Söylemez, Haluk; Sancaktutar, Ahmet Ali; Yıldırım, KadirAmaç: Bu çalışmanın amacı, prostat spesifik antijen (PSA) değerleri 4 ng/ml altında olan hastaların prostat biyopsi sonuçlarını değerlendirmektir. Gereç ve yöntem: Kliniğimizde Ocak 2005-Aralık 2011 tarihleri arasında prostat kanseri şüphesi olan ve total PSA değeri 4 ng/ml’nin altında olan 61 hastadan alınan prostat biyopsisinin sonuçları retrospektif olarak değerlendirildi.Bulgular: Yaşları 41 ile 74 arasında değişen ve PSA ortalaması 2.5 ng/ml olan 63 olguya Transrektal Ultrasonografi (TRUS) eşliğinde prostat biyopsisi yapıldı. On iki hastada (%19) prostat kanseri tespit edildi. Biyopsi sonucu prostat kanseri olan bu hastaların ortalama Gleason skoru 6.8 (5-7), tümor pozitif kor sayısı ise 3 idi. Sonuç: Prostat spesifik antijen değeri 4 ng/ml’nin altında olan olgularda kanser oranımız %19 olup, önceki raporlarla uyumlu bulunmuştur.Öğe Effectiveness and safety of ureteroscopy in pregnant women: a comparative study(Springer, 2013) Bozkurt, Yasar; Soylemez, Haluk; Atar, Murat; Sancaktutar, Ahmet Ali; Penbegül, Necmettin; Hatipoglu, Namik Kemal; Bodakci, Mehmet NuriThe aim of this study was to investigate the efficacy and safety of ureteroscopy (URS) in pregnant patients compared with non-pregnant patients. We reviewed the cases of 41 pregnant and 62 non-pregnant women who developed ureteral stones and were treated with URS in our center between April 2005 and September 2011. A semi-rigid 9.5 F ureteroscope was used. The calculi were fragmented with pneumatic lithotripsy or a holmium laser, and if necessary, a double-J (JJ) stent was inserted during the procedure. Among the pregnant women, the mean gestation period was 23.22 +/- 4.61 weeks (range 13-34), and the mean number of pregnancies per patient was 3 +/- 2.02 (range 1-10). The mean ages of the pregnant and non-pregnant patients were 27.41 +/- 5.79 and 28.54 +/- 7.94 years, respectively (p = 0.734). There were no statistically significant differences in stone localization, anesthesia type, stone diameter, methods of stone manipulation, JJ stent insertion rate, hospitalization length, or operative times between the two groups. For pregnant and non-pregnant patients, the stone-free rates achieved in a single session were 87.8 and 85.5 %, respectively (p = 0.737). There was no statistically significant difference in preoperative and postoperative complication rates between the two groups. The positive urine culture rate was statistically significantly higher for pregnant patients than non-pregnant patients (29.3 vs. 11.3 %; p = 0.021). We did not observe any serious obstetric complications. URS is a safe and reasonable treatment option for pregnant patients with ureteral stones refractory to medical treatment during pregnancy.Öğe Effectiveness of 4.5 F semirigid ureteroscope (Mini-URS) in the management of ureteral stones in children younger than 3 years of age(Aves, 2011) Sancaktutar, Ahmet Ali; Atar, Murat; Soylemez, Haluk; Bozkurt, Yasar; Penbegül, Necmettin; Bodakci, Mehmet Nuri; Gumus, HaticeObjective: We investigated the effectiveness of ureteroscopy (URS) performed with the smallest caliber (4.5 F) semirigid ureteroscope in children younger than 3 years. Materials and methods: URS was performed with a 4.5 F semirigid ureteroscope (Mini-URS). The operative outcomes of 16 children [7 females, 9 males; mean age 30.5 months (range 10-36 months)] who underwent URS in our clinics were evaluated retrospectively. Results: The mean stone diameter was 5.1 mm (range 3-15 mm). A Holmium: YAG laser lithotripter was used. Double J stents were inserted in 3 patients, while ureteral catheterization was performed in 6. In 7 patients, we were unable to insert a double J stent. At the end of the first postoperative week, 13 (84%) patients were completely stone-free. Double J stents were inserted in two patients because of poor endoscopic visualization and inadequate stone fragmentation. In these patients repeat URS was performed to retrieve residual stones during removal of the double J stents. After 1 month, 15 (93.75%) patients were stone-free. No perioperative or early postoperative complication was observed in any patient. Conclusion: URS performed with a 4.5 F semirigid ureteroscope is an ideal alternative for retrieving ureteral stones, with lower complication rates, faster ureteral engagement, and shorter operating times, even in very young patients.Öğe EFFECTIVENESS OF 4.5 F SEMIRIGID URETEROSCOPE (MINI-URS) IN THE MANAGEMENT OF URETERAL STONES IN CHILDREN YOUNGER THAN 3 YEARS OF AGE(Mary Ann Liebert, Inc, 2012) Sancaktutar, Ahmet Ali; Atar, Murat; Soylemez, Haluk; Bozkurt, Yasar; Hatipoglu, Namik Kemal; Penbegül, Necmettin; Bodakci, Mehmet Nuri[Abstract Not Available]Öğe Effects of acute exercise on the diameter of the spermatic vein, and duration of reflux in patients with varicocele(Informa Healthcare, 2013) Atar, Murat; Soylemez, Haluk; Oguz, Fatih; Beytur, Alt; Altunoluk, Bulent; Kahraman, Bayram; Islamoglu, YahyaObjective. The aim of this study was to investigate the effects of acute exercise on the diameter of the spermatic vein, and on the duration of reflux in patients with varicocele. Material and methods. The study included 38 patients with complaints of infertility and scrotal pain between 2009 and 2010. The diagnoses were made by physical examination and colour Doppler ultrasound, with both performed before and after exercise tests. Results. The mean age of the participants was 25.7 +/- 4.9 years. During the first examination, the grades of the varicoceles detected were as follows: grade I, n = 7; II, n = 10; and III, n = 21. The diameters of veins in patients with grades I, II and III varicocele were 2.1 mm, 2.9 mm and 4.2 mm, respectively, before exercise, whereas they were 2.6 mm, 3.2 mm and 4.3 nun, respectively, after exercise. In patients with grade I varicoceles, compared with pre-exercise values, the diameter of the left spermatic vein and duration of reflux measured during Valsalva manoeuvres were increased significantly after exercise (p = 0.042 and p = 0.034, respectively); similar results were obtained for the patients with grade II varicoceles (p = 0.007 and p = 0.008, respectively). However, the minimal relative increase in cases with grade III varicoceles was not statistically significant (p > 0.05). Conclusions. This study demonstrates that acute exercise increases the spermatic vein diameter and reflux time in patients with varicoceles. These outcomes demonstrate that acute exercise may be an aggravating factor for varicocele, as seen in chronic exercise.