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    Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study
    (Elsevier Science Bv, 2016) Rodriguez, Ana M.; Asoglu, Mehmet R.; Sak, Muhammet Erdal; Tan, Alai; Borahay, Mostafa A.; Kilic, Gokhan S.
    Objective: Our objective was to estimate the incidence of uterine leiomyosarcoma in patients with leiomyomas following laparoscopic supracervical hysterectomy and myomectomy procedures. Study design: For this study, we analyzed records of 13,964 women aged 25-64 years who underwent laparoscopic supracervical hysterectomies or myomectomies for leiomyomas from 2002 to 2011 using Clinformatics DataMart. Patient records were divided into two groups: history of laparoscopic supracervical hysterectomy and history of myomectomy. Subjects were tracked to identify diagnosis of leiomyosarcoma within 1 year of the procedure. We analyzed data from the 25-39, 40-49, and 50-64 age brackets. Evidence was obtained from a cohort study from national private insurance claims in the US. Results: Our results showed the incidence of occult leiomyosarcoma developing within 1 year following supracervical hysterectomy using a laparoscopic-assisted approach are 9.8, 10.7, and 33.4 per 10,000 for the 25-39, 40-49, and 50-64 age brackets, respectively; the overall incidence rate is 13.1 per 10,000. The incidence rate of occult leiomyosarcoma developing within 1 year following myomectomy using a laparoscopic-assisted approach are 0.0, 33.8, and 90.1 per 10,000 for the 25-39, 40-49, and 50-64 age brackets, respectively; the overall incidence rate is 17.3 per 10,000. Conclusion: Our analysis shows the overall risk of being diagnosed with occult leiomyosarcoma is 12.9 per 10,000 in laparoscopic-assisted supracervical hysterectomy and myomectomy for patients younger than 49. There is no evidence of occult leiomyosarcoma 1 year after operation for patients younger than 40 who underwent laparoscopic myomectomy. (C) 2015 Published by Elsevier Ireland Ltd.
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    Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study (vol 197, pg 31, 2016)
    (Elsevier Science Bv, 2016) Rodriguez, Ana M.; Zeybek, Burak; Asoglu, Mehmet R.; Sak, Muhammet Erdal; Tan, Alai; Borahay, Mostafa A.; Kilic, Gokhan S.
    [Abstract Not Available]