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    Diagnostic contribution of focal cortical dysplasia MRI imaging findings and ADC values
    (Springer, 2019) Aslan, Aydin; Deniz, Muhammed Akif; Deniz, Zelal Tas; Turmak, Mehmet; Ekici, Faysal
    BackgroundFocal cortical dysplasia (FCD) is a condition that often interferes with the cranial mass. Knowledge of focal cortical dysplasia magnetic resonance imaging (MRI) characteristics is of utmost importance for diagnosis. This study aimed to determine the diagnostic contribution of cranial MRI and the apparent diffusion coefficient (ADC) in FCD.ResultsCranial MRI revealed subcortical hyperintensity (SCH) in 52 patients (82.5%), blurring of the gray-white matter (GWM) interface (blurring) in 52 patients (82.5%), cortical thickening (CT) in 48 patients (76%), cortical signal increase (CSI) in 41 patients (65%), and transmantle sign (TMS) in 29 patients (46%). All of the FCDs had a diffusion increase in diffusion-weighted images (DWIs). The mean ADC value at the lesion level was 1.087 x 10(-3) mm(2)/s (0.82/1.316 x 10(-3) mm(2)/s), which was significantly higher than the mean ADC value measured from the contralateral symmetric region (0.758 x 10(-3) mm(2)/s, 0.678/0.872 x 10(-3) mm(2)/s, p = 0.001).ConclusionResults of this study revealed that the most common MRI findings in FCD patients are SCH, blurring, and CT. These findings aid in an easier diagnosis in patients with suspected FCD. All of the lesions studied here in had a diffusion increase in DWI. The quantitative mean ADC values detected in the differential diagnosis of other lesions with a diffusion increase can be used as a reference. Therefore, in addition to the ADC values and electroencephalography (EEG) findings, the conventional MRI findings of FCD, which is resistant to medical treatment, can help to facilitate the diagnosis of FCD, which can be treated with surgery.
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    Evaluation of the multi-slice computed tomography outcomes in diaphragmatic injuries related to penetrating and blunt trauma
    (Elsevier Science Inc, 2018) Turmak, Mehmet; Deniz, Muhammed Akif; Ozmen, Cihan Akgul; Aslan, Aydin
    Purpose: Traumatic diaphragmatic rupture is a diagnostic challenge for both surgeons and radiologists and generally occurs secondary to blunt and penetrating trauma of thoracoabdominal region. Material and methods: 56 patients who underwent surgical. procedure due to blunt or penetrating trauma were included to the study. Results: There were 37 diaphragmatic ruptures in the left side and 19 patients in the right side. The most common radiological finding was the direct monitoring of defect (54,3%). Conclusion: Findings suggestive of diaphragmatic rupture must be carefully evaluated in patients with blunt or penetrating thoracoabdominal trauma.
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    Investigation of the arterial intima-media thickness in Behcet's disease patients without vascular complaints
    (Sage Publications Ltd, 2018) Kankilic, Nazim; Aslan, Aydin; Karahan, Oguz; Demirtas, Sinan; Caliskan, Ahmet; Yavuz, Celal
    Objectives Behcet's disease is a multisystemic, inflammatory disease. Various factors have been implicated in the disease, including genetics, infections, immunoglobulins, immune complexes, antibodies, and oxidative stress. However, the underlying etiopathogenesis remains unclear. Behcet's disease can occur with or without vascular involvement. This prospective study investigated the relationship between the intima-media thickness of the major arteries, in addition to other factors affecting the disease process, in Behcet's disease without vascular involvement. Methods Twenty-four patients (average age: 38.5010.931) without vascular involvement or any vascular complaints who were diagnosed with Behcet's disease were included in the study. Sixteen healthy subjects (average age: 39.757.793) were included as a control group. Demographic information and medical histories were recorded, and routine blood tests were performed in both groups. The intima-media thickness of the subclavian, axillary, femoral, and carotid arteries of all the participants were recorded using Doppler ultrasonography. The data were then subjected to intergroup statistical and correlation analyses. Results There were no significant differences between the arterial intima-media thickness values of the Behcet's disease patients and those of the control group (p>0.05). However, there was a significant difference between the neutrophil-lymphocyte ratio (p=0.004), low-density lipoprotein (p=0.007), and triglyceride (p=0042) levels of the two groups. Significant correlations were found between intima-media thickness and neutrophil-lymphocyte ratio levels (p=0.012) and the disease duration (p=0.030). There was also a significant correlation between the intima-media thickness of the femoral artery and disease duration (p=0.014). Conclusions The results showed that the duration of illness had a significant effect on arterial intima-media thickness in Behcet's disease. Blood neutrophil-lymphocyte ratio levels were also associated with increased intima-media thickness.