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    Association Between the Rh Blood Group and the Covid-19 Susceptibility
    (Akad Doktorlar Yayinevi, 2020) Arac, Esref; Solmaz, Ihsan; Akkoc, Hasan; Donmezdil, Suleyman; Karahan, Zulkuf; Kaya, Safak; Mertsoy, Yilmaz
    We aimed to investigate whether there is a predisposition to COVID-19 with ABO and Rh blood group systems. This study was a retrospective study that investigate the patients admitted to our hospital between March 16 -May 20 due to Covid-19 pandemic and conducted with data revealed from the hospital Information Management System A total of 392 patients were included in this study, including 227 PCR test positive patients with blood group information in the system and 165 possible patients with CT findings in favor of Covid-19. Data from a blood group study conducted with 127091 people in our province in 2019 were used as a control group. In our study, a significant increase was observed in the blood group A in patients diagnosed with Covid-19, and a decrease was found in the blood groups B, AB and especially O. However, statistical analysis showed no significant difference between Covid-19 patients and healthy individuals in terms of ABO blood group system. When analyzed in terms of Rh blood group system, it was found that Rh positivity was statistically significantly higher in patients with Covid-19 (p= 0.000). Our study suggests that the Rh (-) blood group is protective and the Rh (+) blood group is predisposed to Covid 19 significantly. We think that it is valuable because it is the first study to reveal the relationship between Covid-19 and blood type in our country and the only one to reveal the relationship between Covid-19 and Rh (+) in the world literature.
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    Can clomiphene citrate resistance be predicted by RDW-CV levels in infertile women with PCOS?
    (Wolters Kluwer Medknow Publications, 2019) Peker, Nurullah; Ege, Serhat; Bademkiran, Muhammet Hanifi; Aydin, Edip; Karacor, Talip; Obut, Mehmet; Arac, Esref
    Objective: To identify whether red blood cell distribution width coefficient of variation (RDW-CV) and mean platelet volume (MPV) levels can predict clomiphene citrate resistance (CC-R) in infertile, anovulatory females with polycystic ovarian syndrome (PCOS). Methods: A total of 89 infertile patients who were admitted to a tertiary center diagnosed with non-obese PCOS were included in this study. The patients were divided into two groups: the first group comprised 53 non-obese patients with PCOS and CC-R, and the second group included 36 non-obese patients with PCOS and CC-S. RDW-CV, RDW-SD, and MPV values, along with routine whole blood count parameters were compared between the groups. Results: RDW-CV values were found to be significantly higher in the patients with CC-R compared to those with CC-S (P < 0.05). The sensitivity, specificity, positive, and negative predictive values were found to be 69%, 58.1%, 34.5%, and 12.5%, respectively, at an RDW-CV level of 12.85. The odds ratio was calculated as 3.077 (95% CI 1.245-7.603) in terms of the cut-off point. Conclusion: We think that RDW-CV which is a marker of inflammation is a simple, cheap, and accessible marker for the prediction of CC resistance.
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    Organic or psychosomatic? A cross-sectional study Organic or psychosomatic?
    (Bayrakol Medical Publisher, 2022) Donmezdil, Suleyman; Arac, Esref; Yesildal, Mahir; Guleken, Mehmet Diyadin; Tuzun, Abidin
    Aim: Symptomatic treatments of psychosomatic symptoms are not successful because they cannot solve true etiological causes. To resolve the disorder, it is first necessary to investigate and diagnose the underlying cause and persuade the patient to use the appropriate drugs. In this study, it was aimed to make suggestions in order to identify patients who may have psychiatric symptoms and to prevent unnecessary invasive procedures by scanning psychosomatic symptoms prior to endoscopy indication. Material and Methods: The Cornell index, Beck depression and Anxiety scales, and the Somatization scale were applied to 140 patients whose EGD procedure was planned. The patients were divided into three groups as normal endoscopic examination, antral gastritis, and other disease diagnoses (erosive gastritis, gastric ulcer, etc.). Beck Depression and Beck Anxiety Inventory scores were statistically lower in other diagnostic groups than in normal endoscopic findings and antral gastritis groups. Also, scores on the somatization scale were significantly higher in normal endoscopic findings and antral gastritis groups compared to other diagnostic groups. Results: In patients who underwent EGD, the process was found to be more likely to cause normal endoscopic examination as the age decreased. In addition, somatization, Cornell index, anxiety and depression scores were higher at a young age. The Cornell Medical Index showed a significantly higher sub-score of the strong neurotic structure in the antral gastritis group compared to the other groups. Similarly, there were significantly higher scores for the subscales of depression, irritability-anxiety, fear-startle, psychosomatic symptoms, hypochondriasis, and gastrointestinal disorders in the antral gastritis group compared to other diagnostic groups Discussion: Our results show that applying the somatization scale or an equivalent screening scale to screen psychiatric symptoms before seeking endoscopic examination, especially in the young population, can provide early treatment and prevent increased treatment costs.