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Öğe Effect of energy deficiency during late pregnancy in chios ewes on free fatty acids, ?-hydroxybutyrate and urea metabolites(Tubitak Scientific & Technological Research Council Turkey, 2006) Durak, Mehmet Hanifi; Altiner, AysenPregnant Chios ewes with high twin-lambing rates fed a low energy ration during the final periods of pregnancy were studied. The aim of this study was to determine whether pregnancy toxemia occurred in these ewes by monitoring the changes in the concentrations of serum free fatty acids (FFAs), plasma beta-hydroxybutyrate (beta-HB) and urea. Thirty-eight Chios ewes were used. The animals were divided into 3 groups: pregnant normal energy (PNE), pregnant low energy (PLE), and non-pregnant normal energy (N-PNE). On day 105 of gestation, the animals were begun to be fed with the treatment rations. The feeding regime was continued until lambing. Blood samples were taken into tubes with and without anticoagulant from the jugular vein on days 120, 127, 134, 141, and 148 during gestation. The ewes in PLE had higher concentrations of FFAs on days 134 and 148 compared to those in PNE. beta-HB concentrations in PLE animals were always higher than those in PNE. No difference was found between PNE animals and N-PNE animals. Plasma urea concentration in PNE decreased on day 127, and then continuously increased to a significant [eve] on day 148. It is concluded that an energy intake of greater than 10 MJ/kg ME should be ensured for pregnant ewes in late pregnancy, although an energy level of 8.0 MJ/kg ME does not cause a serious energy deficiency and does not cause pregnancy toxemia.Öğe Serum Ceruloplasmin Levels in Ewes Fed Deficient-Energy During Late Pregnancy(Medwell Online, 2010) Gursel, Feraye Esen; Durak, M. Hanifi; Altiner, AysenThe aim of the study was to investigate the changes in serum ceruloplasmin levels of ewes fed deficient-energy during late pregnancy. Thirty Chios ewes at 4-6 years of age were used in the study. On day 105 after random mating, the ewes were subjected to ultrasound examination to determine pregnancy. After that they were divided into three groups: Pregnant Normal Energy (PNE, n = 10), Pregnant Deficient Energy (PDE, n = 10) and Non-Pregnant Normal Energy (N-PNE, n = 10). From the mating day up to the day 105, all ewes were fed in according to the ration of N-PNE group. On day 106 of gestation, the animals were begun to be fed the treatment rations. Blood samples were taken from the jugular vein into the tubes before feeding in the morning on days 120, 127, 134, 141 and 148 during gestation. Serum ceruloplasmin levels were not statistically different between groups except day 148. On day 148, serum ceruloplasmin levels in the pregnant deficient group were significantly higher than in the other two groups (p<0.05). They were significantly higher in the pregnant normal energy group than in the non-pregnant normal energy group and were significantly lower in the pregnant normal energy group than in the pregnant deficient group (p<0.05). In the study, serum ceruloplasmin level became a sensitive indicator of feed deficiency in the last days of pregnancy. Thus, variations in this antioxidant in ewes with pregnancy toxemia may be of considerable clinical importance.