Yazar "Aliosmanoglu, Cigdem" seçeneğine göre listele

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    Pediatric en bloc kidney transplantation to adult recipients: A case report
    (Aves, 2012) Aliosmanoglu, Ibrahim; Gul, Mesut; Kapan, Murat; Hakseven, Musluh; Aliosmanoglu, Cigdem; Tekes, Firat
    Kidney transplant is one of the most important treatment options in terminal phase kidney failure. The increase of patient waiting lists has pushed transplant centers towards using marginal donors. Although en bloc kidney transplant has been applied since 1970, technical complications, graft thrombosis and the worry of hyperfiltration damage has kept it limited in our country. Our aim in this study is to keep the en bloc kidney transplant on the agenda, which is done rarely from a child donor to an adult receiver.
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    Öğe
    Protective Effect of Caffeic Acid Phenethyl Ester on Antituberculosis Drug-Induced Hepatotoxicity in Rats
    (Int College Of Surgeons, 2017) Aliosmanoglu, Cigdem; Erbi, Halil; Aliosmanoglu, Ibrahim; Turkoglu, Mehmet Akif; Ulger, Burak Veli; Turkoglu, Ahmet; Yuksel, Hatice
    Isoniazid and rifampicin are drugs primarily used in antituberculosis treatment. Our aim in this study is to evaluate the effect of caffeic acid phenethyl ester's protective effect on liver function tests and to trace elements in hepatic damage caused by isoniazid and rifampicin on rats. Forty Wistar albino rats were divided into 4 groups. Group 1: Sham, Group 2: caffeic acid phenethyl ester application, Group 3: isoniazid and rifampicin given, Group 4: isoniazid + rifampicin and caffeic acid phenethyl ester application. After 30 days, the rats were sacrificed by taking blood from the heart. Alanine aminotransferase, aspartate aminotransferase, zinc, copper, total antioxidant capacity, total oxidative status, and oxidative stress index levels were evaluated. The rats to which isoniazid + rifampicin + caffeic acid phenethyl ester were given had less oxidative stress and copper levels (P < 0.001, P = 0.019) but have higher zinc levels (P = 0.001) compared to the isoniazid + rifampicin group. Liver enzyme levels were also lower in rats that were given isoniazid + rifampicin + caffeic acid phenethyl ester (P < 0.001). The results of this study suggested that caffeic acid phenethyl ester influences the levels of trace elements (copper and zinc) that are important for the physiologic mechanisms of organisms, reducing liver damage.