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    A case of familial mediterranean fever presenting with isolated dry pleuritis
    (2009) Yildiz T.; Ateş G.; Akyildiz L.; Topçu F.
    Familial Mediterranean fever (FMF), a hereditary disease which is characterised by self limited attacks of fever and serositis, is especially common in Mediterranean region. Colchicine is the most effective drug in preventing the recurrent attacks of the disesae. Since it is a rare condition, we present a patient with FMF who had pleural involvement without radiologic findings.
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    Connecting with guidance counselors in anti smoking campaigns in formal education
    (2009) Ates G.; Akyildiz L.; Yildiz T.; Topcu F.; Polat M.R.
    One of the most important steps in the struggle against tobacco smoking is public training and awareness. For this purpose, teachers carry important responsibilities. This study is aimed to evaluate the rate of smoking, reactions against it, the knowledge about smoking-related disorders, and legal restrictions against smoking in guide teachers (guidance counselors). A self-administered questionnaire was applied to guide teachers in Diyarbakir. Totally 217 teachers (135 male, 82 female, mean age 29.2 ± 4.5 years) were included in this study. Seventy-eighth (35.9%) of them were found to be smokers. More than 90% of them showed supportive attitudes for all the legal preventions except for extremely high cigarette prices, prohibition of smoking in entertainment places such as cafes, restaurants and outdoor places in which various sports, cultural and art activities take place. Almost all of the participants were aware of the health damaging impacts of smoking except its neonatal death and bladder cancer-inducing effects. Owing to their high degree, support for legal restrictions and their knowledge regarding the damaging effects of cigarette smoking on human health, guiding counselors can be actively cooperated in anti-smoking campaigns in formal education.
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    The effectiveness of scoring systems and various biochemical parameters in predicting survival in a respiratory intensive care unit
    (Turkish Biochemistry Society, 2010) Yildiz T.; Gündo?uş B.; Ateş G.; Akyildiz L.; Çelik Y.; Topçu F.; Canoruç N.
    Aim: The aim of the present study was to compare various clinical and biochemical parameters, Acute Physiological and Chronic Health Evaluation II (APACHE II), and Sequential Organ Failure Assessment (SOFA) for their effectiveness in distinguishing surviving and non-surviving patients who had acute respiratory failure (ARF) while in the Respiratory Intensive Care Unit (RICU). Materials and Methods: A prospective observational clinical study was carried out in the RICU of the Chest Disease Clinic. One hundred and sixteen patients were observed. Laboratory parameters and scoring points for the first 24 hours were recorded. Patients' demographic characteristics, biochemical parameters, length of stay at the RICU, and GCS, APACHE II and SOFA scores were also recorded. The primary outcome of the current study was the mortality rate in the RICU. Results: Mortality rate was determined to be 39.6% (46 patients) of 116 patients, although the predicted mortality rate was 49.7%. There was a statistically significant difference between surviving and non-surviving patients in terms of SOFA (p= 0.004, OR= 1.33, CI= 1.10-1.61), INR (p = 0.02, OR = 3.95, CI = 1.30-12.07), albumin (p= 0.02, OR= 2.58, CI= 1.17-5.64), and PCO2 levels (p= 0.005, OR= 1.04, CI= 1.01-1.06), respectively. Conclusion: Our results suggest that the mortality rate may be higher when SOFA, INR, albumin and PCO2 abnormalities are seen. Co-morbidities such as non-pulmonary organ dysfunction and metabolic disorders other than respiratory failure may have contributed additionally to increased mortality risk for patients who were admitted to the RICU. These parameters should be taken into account when ARF patients are admitted to the RICU. 2010 © TurkJBiochem.com.
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    Should sputum ARB evaluation done in patients with squamous cell cancer?
    (2006) Akyildiz L.; Abakay A.; Topçu F.; Aritürk-Abakay Ö.
    A seventy one year old /man patient was admitted to our hospital with cough, sputum hemoptysis and weight lose that were present for two months. Physical examination revealed bilateral rales. On his chest X-ray caviter lesion with pericavitier infiltration was seen in middle zone. Thorax CT showed the infrahiler mass including irreguler bordered, thick walled cavitier lesion. Bronchoscopic endobronchial biopsy revealed squamous cell cancer and caseifie granulomatous bronchit in the entrance of right lower lobe. Anti-Tbc chemotherapy had been started with four drugs (HREZ) because the sputum ARB results were positive. The patient died because of respiratory failure in fifteenth day of therapy. One month prior to admission of the patient to our hospital, bronchoscopic endobronchial biopsy that was done in an another center revealed squamous cell cancer and also granulomatous process but despite thus any other diagnostic evaluation (such as sputum ARB) had not been performed. We aimed to notify that sputum ARB evaluation should be done in all patients with pulmonary cavitier lesions for differential diagnosis especially in countries that tuberculous is a common infection like our country.