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Öğe Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey(Wiley, 2018) Uzun, Soner; Gurel, Mehmet S.; Durdu, Murat; Akyol, Melih; Karaman, Bilge Fettahlioglu; Aksoy, Mustafa; Aytekin, SemaBackground Cutaneous leishmaniasis ( CL) is a vector- born parasitic disease characterized by various skin lesions that cause disfiguration if healed spontaneously. Although CL has been endemic for many years in the southern regions of Turkey, an increasing incidence in nonendemic regions is being observed due to returning travelers and, more recently, due to Syrian refugees. Thus far, a limited number of national guidelines have been proposed, but no common Turkish consensus has emerged. Objectives The aim of this study was to develop diagnostic and therapeutic guidelines for the management of CL in Turkey. Methods This guideline is a consensus text prepared by 18 experienced CL specialists who have been working for many years in areas where the disease is endemic. The Delphi method was used to determine expert group consensus. Initially, a comprehensive list of items about CL was identified, and consensus was built from feedback provided by expert participants from the preceding rounds. Results Evidence- based and expert- based recommendations through diagnostic and therapeutic algorithms according to local availability and conditions are outlined. Conclusion Because CL can mimic many other skin diseases, early diagnosis and early treatment are very important to prevent complications and spread of the disease. The fastest and easiest diagnostic method is the leishmanial smear. The most common treatment is the use of local or systemic pentavalent antimony compounds.Öğe Kronik mukokutanöz kandidiyazis: nadir bir hastalık(Doğu Karadeniz Deri ve Zührevi Hastalıklar Derneği, 2022) Erat, Tuğba; An, İsa; Öztürk, Murat; Aksoy, Mustafa; Ayhan, Erhan; Uçan, Egemen"Editöre mektup" makale türünde Mucosa için özet sunulmasına gerek yoktur.Öğe Neutrophil / Iymphocyte ratio, platelet / Iymphocyte ratio, mean platelet volume and C-reactive protein values in psoriatic arthritis patients(İnönü Üniversitesi Tıp Fakültesi, 2019) An, İsa; Uçmak, Derya; Öztürk, Murat; Aksoy, Mustafa; Yıldız, İsmail; Ucan, EgemenAim: Studies have shown that neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio(PLR), mean platelet volume(MPV) and C-reactive protein(CRP) are higher in psoriatic arthritis patients than in the control group. In this study, NLR, PLR and MPV values of patients with psoriatic arthritis were calculated and if these parameters were related to CRP levels. Material and Methods: 74 psoriatic arthritis patients and 77 healthy controls without any systemic, infectious and autoimmune diseases were included in the study. Patients were divided into two groups according to their CRP values: normal (0-0.5 mg / dl) and high (> 0.5 mg / dl) Results: NLR, MPV and CRP values in the patient group were significantly higher than the control group. PLR value in the patient group was higher than the control group but the difference between them was not statistically significant. There was a statistically significant relationship between CRP and NLR and MPV values in psoriatic arthritis patients. Conclusion: Since NLR and MPV were significantly higher in psoriatic arthritis patients than in the control group and there was a statistically significant relationship with CRP elevation, it was thought that they were appropriate parameters to show inflammation in patients with psoriatic arthritis.Öğe Ten cases of aquagenic syringeal acrokeratoderma revealed during the COVID-19 outbreak(Wiley, 2021) Erhan, Ayhan; Yıldırım, Cihat; Aksoy, Mustafa; Ebik, Berat; Öztürk, Murat; Akelma, HakanAquagenic syringeal acrokeratoderma (ASA) is a rare, acquired disease affecting predominantly young women. It is characterised by the development of hypopigmented, translucent, flat‐topped, oedematous papules and plaques that form hyperwrinkling or keratoderma.1 It occurs after 3‐5 minutes of contact with water and resolves when the hand dries.1 Although its aetiology is not known exactly, it has been suggested that the disease may develop due to genetic predisposition or diseases such as cystic fibrosis, focal hyperhidrosis and Raynaud's phenomenon.2, 3 However, increased personal hygiene measures such as wearing personal protective equipment, excessive hand washing and disinfection in the COVID‐19 epidemic may play a role in the aetiology of ASA.5 Here we present ten cases with a very short history of ASA where lesions were first seen after the COVID‐19 outbreak.
