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Öğe Does 900 MHZ GSM mobile phone exposure affect rat brain?(Taylor & Francis Inc, 2004) Dasdag, S; Akdag, MZ; Aksen, F; Bashan, M; Buyukbayram, HThis study investigated the effects of cell phone exposure on the fatty acid composition in phospholipids, malondialdehyde concentration, p53 immune reactivity and histological structure of the rat brain. Sixteen Sprague-Dawley rats were divided into two groups of eight, sham and experimental (speech conditions). The rats were confined to Plexiglas cages, and cellular phone were placed 0.5 cm under the cages. For the experimental group, cellular phones were activated 20 minutes per day, 7 days a week, for 1 month. For the sham group, the cellular phones were placed beneath the cages with the phones turned off. The Whole Body Average SAR (rms) was 0.52 W/kg and 1 g averaged peak SAR (rms), 3.13 W/kg. The Mann-Whitney U-test was used for statistical. comparisons of groups.. Histological alteration and changes in brain phospholipid fatty acids composition were not observed in rat brains. Immunohistochemical staining of brain tissue shown that p53 immunoreactivity was not affected by cell phone exposure. Malondialdehyde concentration in exposed brains was significantly higher than sham (p < 0.05).Öğe The effects of extremely. low. frequency magnetic field on inner ear, parotis and submandibular gland(Taylor & Francis Ltd, 2002) Aksen, F; Akdag, MZ; Meric, F; Cureoglu, S; Yilmaz, F; Kaya, AExperiments using sixteen male Spraque-Dawley rats were carried out to determine possible effects of Extremely Low Frequency Magnetic Field (ELF MF) on inner ear, parotis and submandibular glands. The rats were seperated into two. groups of 8, one control and one experimental group, The rats in the experimental groups were exposed to ELF MF (1.35 mT) 2 hour/a day during two months. Eight rats of sham group were treated like experimental group except ELF MF exposure. The rats were sacrificed under ketalar anesthesia immediately after last exposure. Then parotis, submandibular gland and total ear of rats were removed for. histopathological examination. The histopathological results obtained indicate that ELF magnetic field didn't affect parotis, submandibular glands and inner ear.Öğe The effects of whole body cell phone exposure on the T1 relaxation times and trace elements in the serum of rats(Taylor & Francis Inc, 2004) Aksen, F; Dasdag, S; Akdag, MZ; Askin, M; Dasdag, MMThe. objective of this study was to investigate the effects of radiofrequency radiation emitted from cellular phones on: (1) trace elements such as manganese, iron, copper, zinc, (2) T1 relaxation times in serum, and (3) rectal temperature of rats. exposed to microwave radiation emitted. from cellular phones. Sixteen Sprague-Dawley rats were separated into two groups of eight, one sham-exposed (control) and one expo sed (experimental). The rats were confined in Plexiglas cages and a cellular phone was placed 0.5 cm under the cage. For the experimental group, cellular phones were activated 20 min per day, 7 days a week, for I month. For the control group, a cellular phone placed beneath the cage for 20 min a day was turned off. Rectal temperatures were measured weekly. For 250-mW-radiated powers, the whole body average specified absorption rate (SA R) (rms) is 0.52 W/ kg and 1-g-averaged peak SAR (rms) is 3.13 W/kg. The Mann-Whitney U test was used for statistical comparisons of groups. T1 relaxation time and the values of iron and copper in the serum of the experimental group were not changed compared to the control group (p > 0.05). However, manganese and zinc values in the serum of the experimental group were significantly different from the control group (p < 0.05). The difference in rectal temperature measured before and after exposure in the experimental groups was not statistically different from control (p > 0.05).Öğe The preventive effect on bone loss of 50-Hz, 1-mT electromagnetic field in ovariectomized rats(Springer-Verlag Tokyo, 2002) Sert, C; Deniz, M; Düz, MZ; Aksen, F; Kaya, AOsteoporosis is a common health problem, especially in the elderly and in women after menopause. Although there are some treatment methods, they impose serious side effects. Recently, the use of an electromagnetic field (EMF) has been a promising candidate for better treatment of osteoporosis. In the present study, we investigated the preventive effects of low-frequency (50 Hz), low-intensity (1 mT), and long-term (6 weeks) EMF on bone loss in ovariectomized rats. We used 18 female albino Wistar rats (8 unexposed and 10 exposed) to assess the effect of EMF. We examined the mineralization and the morphology of the tibia in control and EMF-exposed rats. The cortical thickness of the tibia was increased in EMF-exposed rats (P < 0.002). The levels of Na and K in the tibia were significantly increased in rats exposed to EMF (P < 0.001; P < 0.002, respectively). We also observed an increased blood alkaline phosphatase (ALP) level after EMF exposure (P < 0.05). No significant differences in the levels of Ca, Mg, Li, or creatine were found between the exposed and unexposed groups. Our data support the notion that an EMF may prove to be an effective treatment method for osteoporosis and other abnormalities related to bone loss.