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Öğe Cervical biopsy specimens and human papilloma virus positivity in patients with external genital warts(I R O G Canada, Inc, 2002) Akdeniz, S; Yaldiz, M; Akdeniz, NCervical biopsy specimens were taken from 16 women with external genital warts in order to diagnose concomitant cervical human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN) according to pathology. Positive HPV infection was detected 56% (9/16) of the patients. Among those patients 66% (6/9) had concurrent subclinical low-grade CIN lesions. One of those patients had a high-grade CIN lesion. It is concluded that cervical HPV infection was rather common in women with external genital warts and it is valuable to examine cervical HPV infection by biopsy to detect concomitant CIN.Öğe The comparison of amino-terminal probrain natriuretic peptide levels in preeclampsia and normotensive pregnancy(Walter De Gruyter Gmbh, 2005) Kale, A; Kale, E; Yalinkaya, A; Akdeniz, N; Canoruç, NObjective: The purpose of this study was to evaluate the levels of amino-terminal probrain natriuretic peptide (Nt pro-BNP) in preeclampsia in comparison with normotensive pregnancy. Materials and methods: Women with preeclampsia (proteinuria >= 300 mg/24 In and at least two readings of systolic blood pressure >= 140 mm Hg and diastolic blood pressure >= 90 mm Hg) (n=32 mild preeclampsia and n=8 severe preeclampsia) were compared with normotensive women (n=40). Serum Nt pro-BNP was measured using an electrochemiluminescence immunoassay (ECLIA) method (Nt pro-BNP, Roche) with a Roche modular analytics E170 immunoassay analyzer. Statistical analysis was carried out by the Student t-test, and a P value of <0.05 was accepted as statistically significant. Results: The median serum Nt pro-BNP was 430 +/- 28.91 pg/mL in preeclampsia. The levels of serum Nt pro-BNP were 74 16.82 pg/mL in normotensive pregnant women (P < 0.001) and significantly higher in women with preeclampsia (P < 0.001). Conclusion: The higher levels of serum Nt pro-BNP in preeclamptic women may be an indicator of high left-ventricular filling pressure, and indicate left-ventricular diastolic dysfunction.Öğe Peritoneal tuberculosis mimicking ovarian pathology. A series of 11 cases(Saudi Med J, 2006) Kale, A; Akdeniz, N; Akyildiz, L; Kale, E; Gul, T[Abstract Not Available]Öğe Pregnancy complicated by superior vena cava thrombosis and pulmonary embolism in a patient with Behcet disease and the use of heparin for treatment(Saudi Med J, 2006) Kale, A; Akyildiz, L; Akdeniz, N; Kale, EBehcet disease is a multisystemic vasculitis of unknown origin. Vascular involvement has been considered to result from systemic vasculitis, occurs in 5-10% of these patients. We report a 34-year-old pregnant woman complicated by superior vena cava thrombosis, and pulmonary embolism in a patient with Behcet disease.Öğe The relationship between thrombophilic mutations and preeclampsia: a prospective case-control study(K Faisal Spec Hosp Res Centre, 2006) Yalinkaya, A; Erdemoglu, M; Akdeniz, N; Kale, A; Kale, EBACKGROUND: Preeclampsia and its association with thrombophilia remain controversial, dueto inconsistent results in different studies, which include different ethnic groups, selection criteria, and patient numbers. The aim of this study was to determine the relationship between thrombophilia and preeclamptic patients in our region. METHODS: In a prospective case-control study, we compared 100 consecutive women with preeclampsia and eclampsia (group 1) with 100 normal pregnant women (group 2). All women were tested two months after delivery for mutations of factor V Leiden, methylenetetrahydrofolate reductase (MTHFR), and prothrombin gene mutation as well as for deficiencies of protein C, protein S, and antithrombin III. RESULTS: A thrombophilic mutation was found in 42 (42%) and 28 (28%) women in group 1 and group 2, respectively (P=0.27, OR 1.5, 95% CI 1.0-2.2). The incidence of Factor V Leiden mutation (heterozygous), prothrombin mutation (heterozygous), prothrombin mutation (homozygous), MTHFR mutation (homozygous) was not statistically significant in group 1 compared with group 2 (P > 0.05). Also, deficiencies of protein S, protein C, and antithrombin III were not statistically significant in group 1 compared with group 2 (P > 0.05). CONCLUSION: There was no difference in thrombophilic mutations between preeclamptic patients and normal pregnant women in our region. Therefore, we suggest that preeclamptic patients should not be tested for thrombophilia.Öğe Spontaneous rupture of the ovarian artery following spontaneous vaginal birth(Saudi Med J, 2005) Kale, A; Akdeniz, N; Erdemoglu, M; Ozcan, Y; Yalinkaya, A[Abstract Not Available]
