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Öğe 900 MHz radiofrequency radiation has potential to increase the expression of rno-miR-145-5p in brain(University of Dicle, 2019) Dasdag S.; Erdal M.E.; Erdal N.; Tasdelen B.; Kiziltug M.T.; Yegin K.; Akdag M.Z.Interaction between radiofrequency radiation (RFR) and miRNA which plays paramount role in growth, differentiation, proliferation, and cell death by suppressing one or more target genes, is still unknown. Therefore, the purpose of this study is to investigate the effects of long term 900 MHz mobile phone exposure on some of the miRNA in brain tissues (sham: 7; Exposure: 7)., which were kept in appropriate laboratory conditions for the second phase of our previous study [5]. It is remembered that rats in the exposure group were exposed to 900 MHz RFR for 3 h per day (7 days a week) for one year. For the aim of this study, expression of miRNAs such as rno-miR-22-3p, rno-miR-24-1-3p, rno-miR-132-3p, rno-miR-145-5p, rno-miR-181a-5p, rno-miR-186-5p, rno-miR-195-5p, rno-miR-219a-5p, rno-miR-221-3p and rno-miR-222-3p were investigated. Results indicated that long-term exposure of 900 MHz RF radiation increased only expression of rno-miR-145-5p (adj P * = 0.047) value where 1g average SAR value in brain was 0.198 W/kg. Our results indicated that chronic exposure of 900 MHz RFR has potential to increase expression of rno-miR-145-5p. Therefore, further studies are necessary to understand the relation between 900 MHz mobile phone exposure and diseases related to the expression of rno-miR-145-5p. © University of Dicle.Öğe Alteration in body composition of elite professional female players in a premier league volleyball bout(2009) Cerit S.; Akdag M.Z.; Dasdag S.; Karakoc Y.; Celik M.In this study, we aimed to investigate the effects of single bout of volleyball on body composition in elite professional female players. Sixteen elite professional female players that play volleyball in a club in Turkish Premier League were enrolled in the study. Prior to one league match (pre-exercise) bioelectric impedance analyzes were performed using a bioelectric impedance analyzer. After the final period (3rd set) of match was ended, bioelectric impedance analyzes were repeated (post-exercise). There were no significantly changes in body mass index, body cell mass, body capacitance, lean body mass, and basal metabolic rate at post-exercise time. Body resistance, reactance and fat mass were all significantly lower than pre-exercise time (p<0.01). On the other hand, extracellular mass increased at post-exercise time, and that significances were found to be p<0.05. As an intense aerobic exercise, single bout of volleyball (three sets) decreases body fat mass at post-exercise time. This change is associated with decreases in body resistance and reactance. Excess lost of body fat may be related to frequently using anaerobic process for energy requirement in volleyball players and prolonged exercise for competition.Öğe The effect of 900 MHZ radiofrequency (RF) radiation on some hormonal and biochemical parameters in rabbits(2009) Karadede B.; Akdag M.Z.; Kanay Z.; Bozbiyik A.In this study, the effect of cell phone frequency 900 MHz radiofrequency (RF) radiation on rabbits' some hormonal and biochemical parameters was investigated. 14 male, adult, New Zealand albino rabbits were separated into two groups as control and experimental (n=7). For the experimental group, rabbits exposed to 900 MHz frequency RF radiation 2 h per day (7 days in a week) for 90 days. Control group rabbits' procedure was the same as experimental group except the exposure of RF. Before the exposure, at first and third month of exposure; Glucose, Creatinin, Na, K, Cl, Calcium, Phosphorus, Total protein, Albumin, Globulin and Magnesium levels and T3, T4, TSH, LH, FSH, Testesteron, Estradiol, Prolactin, Cortisol, ACTH and Growth Hormon levels were determined from rabbits' blood which was taken from V.Marginalis in their right ear. There was not any significant difference in neither hormonal nor biochemical parameters between experimental and control groups before exposure (p>0.05). At first month of RF exposure; there was not any significant difference in biochemical parameters (p>0.05). However, T4, Testesterone, Estradiol, Cortisol and ACTH levels increased but this increasing was not stastistically significant (p>0.05). After third month exposure, it was found that there was not any significant difference in biochemical parameters (p>0.05), but there was an increase at T4, Cortisol and ACTH levels and only increasing in ACTH levels was stastistically significant (p<0.05). It was concluded that 900 MHz RF exposure did not change some important biochemical and hormonal parameters except ACTH levels after 90 days exposure.Öğe Effect of extremely low frequency magnetic fields in safety standards on structure of acidophilic and basophilic cells in anterior pituitary gland of rats: An experimental study(2009) Akdag M.Z.; Dasdag S.; Ketani M.; Sagsoz H.After discovery of magnetite in the brain of several mammalian species including humans, it was suggested that the human brain is sensitive to magnetic fields. The present study investigated the effect of 100 ?T and 500 ?T extremely low frequency magnetic fields (ELF-MF), established guidelines by the International Commission on Non-Ionizing Radiation Protection (ICNIRP) for public and occupational magnetic field exposure limits at 50 Hz, on acidophilic and basophilic cells in the anterior pituitary gland of rats. 30 adult male Sprague Dawley rats were separated into three groups in this study (sham group: 10 and two study groups: 20). Rats in the study (experimental) groups separated equally into two groups that is 100 ?T and 500 ?T exposure groups. First experimental group rats exposed to 100 ?T while second experimental group exposed to 500 ?T ELF-MF for 2 hours per day (7 days in a week) during 10 months. For the sham group, the same experimental procedure was applied to the rats (2 hours/day/7 days in a week for 10 months) except ELF-MF exposure. After ELF-MF and sham exposure, the pituitary gland were removed totally to examine the structure of acidophlic and basophilic cells in the anterior pituitary gland of rats as histomorphometric and histochemical. Affinity against dye in acidophilic and basophilic cells of first experimental groups' rat was found lower than sham group. It means that degranulation may occur in sitoplasmic granuls of these cells. Disappearing in the affinity of Periodic Acid-Shchiff (PAS)-Orange-G in acidophilic and basophilic cells of second exposure group has been indicating high disappearing of granuls in these cells. No significant differences were found between sham and exposure groups in terms of the number of acidophilic and basophilic cells in the anterior pituitary gland (p>0.05). Although degranulation observed in acidophilic cells, the results were not found to be significant between experimental groups (p>0,05). However, degranulated basophilic cells were found significant between experimental groups (p<0,05). In conclusion, it was suggested that long-term ELF-MF exposure, which are the limits for public environmental and occupational magnetic field exposure guidelines, can affect affinity of PAS-Orange G in acidophilic and basophilic cells of the anterior pituitary gland in rats.Öğe The effects of Extremely Low Frequency Magnetic Field on inner ear, parotis and submandibular gland(2002) Aksen F.; Akdag M.Z.; Meric F.; Cureoglu S.; Yilmaz F.; Kaya A.Experiments using sixteen male Spraque-Dawley rats were carried out to determine possible effects of Extremely Low Frequency Magnetic Field (ELF MF) on inner ear, parotis and submandibular glands. The rats were seperated into two groups of 8, one control and one experimental group. The rats in the experimental groups were exposed to ELF MF (1.35 mT) 2 hour/a day during two months. Eight rats of sham group were treated like experimental group except ELF MF exposure. The rats were sacrificed under ketalar anesthesia immediately after last exposure. Then parotis, submandibular gland and total ear of rats were removed for histopathological examination. The histopathological results obtained indicate that ELF magnetic field didn't affect parotis, submandibular glands and inner ear.Öğe Effects of radiofrequencies emitted from mobile phones on teeth and oral tissues(University of Dicle, 2017) Dasdag S.; Yavuz I.; Akdag M.Z.Number of various sources of wireless communication is had been incredibly increased in the recent decade. One of the most popular wireless communication equipment is mobile phones. However, another widespread part of wireless communications is Wi-Fis. As it is known, smart phones has many function such as speaking, Wi-Fi, bluetooth etc. Therefore, their radiofrequency radiation (RFR) level is higher than the first generation mobile phones. It means that smart phones emit higher RFR. The results of studies performed on the effects of RFR on animal or human indicated that mobile phones are not innocent. Because of that RFRs classified as 2B (Possible carcinogen) by World Health Organization in 2011. Most of the studies usually performed on RFR and health focused on the brain tumors and other diseases. No one pay attention to the potential health effects of this electromagnetic pollutant on oral tissues and teeth, which are one of the most RFR exposed parts of heads at the beginning. Although limited number of the studies had been done on oral tissues, the results of the studies are worth considering. Therefore, the aim of this review is to summarize the results of the limited studies here. In conclusion, the results of the studies investigated the effects of RF exposure on oral tissues and teeth indicated that uncontrolled exposures may have potential to cause some dental health problems. Finally, further studies including human studies are necessary to illuminate this topic.Öğe ELF electromagnetic field and strontium ranilate influences on the trace element content of rat teeth(2009) Kaya S.; Akdag M.Z.; Yavuz I.; Celik M.S.; Adiguzel Ö.; Tumen E.C.; Kaya F.A.Exposure to Extremely Low Frequency (ELF) Electromagnetic Field (EMF) emanating from the generation, distribution and utilization of electricity. The major debate in recent years has focused on the possibility that exposure to EMF may result some health consequences such as differentiation on bone constitute. In this study, the effect of ELF-EMFs and strontium ranelate on teeth constitute amount of mineral were investigated in rats. Seventy-five four month old adult female Sprague-Dawley rats were randomly divided into 5 different groups (n = 15). After all applications, some mineral levels such as: Ca, Mg and Zn in rat teeths were determined with Atomic Absorbtion Spectrophotometry (AAS) and the phosphorus content of teeth was determined by Ultraviolet Spectrophotometer (UVS). It was determined that the levels of Ca and P were not statistically different in comparison to Cg-Cnt and between groups (p>0.05). However, it was observed that the levels of Zn significantly alterations between some groups (p<0.05). The levels of Mg in ELF-EMF+OVX, ELF-EMF and OVX groups decreased significantly in comparison to Cg-Cnt group (p<0.05). As a resulf it can be suggested that mineral amount of rat teeth can change after ovariectomy and ELF-EMF exposure, also strontium ranelate treatments can't increase mineral amount of teeth. © Medwell Journals, 2009.
