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    Effects of low-intensity microwave radiation on oxidant-antioxidant parameters and DNA damage in the liver of rats
    (Wiley, 2021) Alkış, Mehmet Eşref; Akdaǧ, Mehmet Zülküf; Daşdağ, Süleyman; 0000-0002-3321-2873; 0000-0003-2826-2734; 0000-0003-1211-9677
    The continuously increasing usage of cell phones has raised concerns about the adverse effects of microwave radiation (MWR) emitted by cell phones on health. Several in vitro and in vivo studies have claimed that MWR may cause various kinds of damage in tissues. The aim of this study is to examine the possible effects of exposure to low-intensity MWR on DNA and oxidative damage in the livers of rats. Eighteen Sprague-Dawley male rats were divided into three equal groups randomly (n = 6). Group 1 (Sham-control): rats were kept under conditions the same as those of other groups, except for MWR exposure. Group 2: rats exposed to 1800 MHz (SAR: 0.62 W/kg) at 0.127 +/- 0.04 mW/cm(2) power density, and Group 3: rats exposed to 2,100 MHz (SAR: 0.2 W/kg) at 0.038 +/- 0.03 mW/cm(2) power density. Microwave application groups were exposed to MWR 2 h/day for 7 months. At the end of the exposure period, the rats were sacrificed and DNA damage, malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG), and total oxidant-antioxidant parameter analyses were conducted in their liver tissue samples. It was found that 1800 and 2100 MHz low-intensity MWR caused a significant increase in MDA, 8-OHdG, total oxidant status, oxidative stress index, and comet assay tail intensity (P < 0.05), while total antioxidant status levels (P < 0.05) decreased. The results of our study showed that whole-body exposure to 1800 and 2100 MHz low-intensity MWR emitted by cell phones can induce oxidative stress by altering oxidant-antioxidant parameters and lead to DNA strand breaks and oxidative DNA damage in the liver of rats. Bioelectromagnetics. (c) 2020 Bioelectromagnetics Society
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    New technique: Measurement of microleakage volume in the marginal gaps of the dental restorations
    (2005) Yavuz, I.; Aydın, A. Haluk; Ülkü, Refik; Dülgergil, Türksel Çoruh; Akdaǧ, Mehmet Zülküf; 0000-0001-6953-747X
    This study investigates the feasibility of a different approach to determining the microleakage volume associated with dental restorations and the relative marginal adaptation deficiency of dog, bovine and human primary teeth in in vitro conditions. It was also researched the appropriateness of using dog and bovine teeth in in vitro studies instead of human teeth. Our method utilizes the molecular characteristics of methylene blue (MB). Within the framework of this study, 60 permanent teeth (20 human, 20 dog and 20 bovine) were used. Class V cavities were prepared in all human, dog and bovine primary teeth and all restorations were made by Composite. These groups were evaluated statistically for dye penetration and microleakage volume measurements using Kruskal-Wallis non-parametric test (p>0.05) and One Way ANOVA, both of which indicated no statistically significant differences (p>0.05). This preliminary investigation showed that the new microleakage volume measurement method might be a valuable tool for the in vitro study of microleakage dynamics around dental restorations. However, this method can be used as a new technique for the determination of microleakage volume. As a result of this study; dog and bovine teeth can be used instead of human teeth.
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    Whole body exposure of rats to microwaves emitted from cell phone does not affect the testes
    (Wiley, 2003) Daşdağ, Süleyman; Akdaǧ, Mehmet Zülküf; Akşen, Feyzan; Yılmaz, Fahri; Başhan, Mehmet; Daşdağ, M. Mutlu; Çelik, Mustafa Salih; 0000-0003-1211-9677; 0000-0001-7965-6229; 0000-0002-1228-9548
    The objective of this study was to investigate the effects of radiofrequency radiation emitted from cellular phones on the lipid composition, malondialdehyde concentration, p53 immune reactivity, sperm count, morphology, histological structure of testes, and on rectal temperature of rats exposed to microwave radiation emitted from cellular phones. Sixteen Spraque-Dawley rats were separated into two groups of eight, sham exposed (control) and experimental. The rats were confined in plexiglas cages specially designed for this study, and cellular phones were placed 0.5 cm under the cages. For the experimental group, cellular phones were activated 20 min per day (7 days a week) for 1 month. For the control group, the cellular phones were placed beneath the cages for 20 min a day, but the phones were turned off. Rectal temperatures were measured weekly. For 250 mW radiated power, the whole body average SAR (rms) is 0.52 W/kg and 1 g averaged peak SAR (rms) is 3.13 W/kg. The Mann-Whitney U-test was used for statistical comparisons of groups. No statistically significant alteration in any of the endpoints was noted. This study found no evidence suggesting an adverse effect of cell phone exposure on measures of testicular function or structure. (C) 2003 Wiley-Liss, Inc.