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Öğe Appendicular tuberculosis: review of 155 published cases and a report of two cases(Urban & Vogel, 2010) Akbulut, S.; Yagmur, Y.; Bakir, S.; Sogutcu, N.; Yilmaz, D.; Senol, A.; Bahadir, M. V.This paper provides an overview of the literature on appendicular tuberculosis (ATB) between 1909 and 2010. We present two cases of primary ATB and a literature review of studies on ATB published in English and accessed via the Pubmed and Google Scholar databases. One hundred fifty-five published cases of ATB were reviewed, and two patients with primary ATB, treated and followed in our clinic, were reported. The age range of the patients (62 females, 60 males and 33 with unnoted gender) was between 2 and 60 years, with a mean age of 27.1 +/- A 10.6 years. Of the patients who had applied to hospital, 59 had acute right lower quadrant pain, 46 had recurrent right lower quadrant pain, 19 had generalized pain, and 10 had chronic abdominal symptoms suggestive of subacute intestinal obstruction, while 47 patients were operated on with a diagnosis of acute appendicitis, 24 with recurrent appendicitis, 19 with TB peritonitis, 14 with mass in the right lower quadrant, 13 with subacute intestinal obstruction, and 7 with ATB. While appendectomy was not performed on 4 patients, one or more of the following procedures were done in the other 151 cases: appendectomy, hemicolectomy, ileocecal resection, or cecectomy. Different anti-tubercular treatment regimens with durations varying from 3 weeks to 18 months were applied to 60 patients. During the follow-up period of 3 weeks to 15 years, mortality occurred in 14 patients, sinus in five, and fistula in one patient. Secondary ATB was detected in 86 patients, primary ATB in 50, and no differential diagnosis could be made in 19 cases. Tuberculosis is a systemic disease with localized manifestations; therefore, anti-TB therapy must be initiated in any patient whose pathologic specimen reveals tuberculosis.Öğe Castleman's disease as cervical mass: a report of three cases and review of the literature(Cic Edizioni Int, 2009) Cakabay, B.; Akbulut, S.; Sezgin, A.; Gomceli, I.; Arikok, A. T.; Ozmen, C. Akgul; Ozbek, E.node hyperplasia involving lymphatic tissue in the neck, mediastinum, abdomen and other areas. Disease was described for the first time in 1956 by Castleman. The etiopathogenesis of the disease is unknown. The disorder can be classified into three histopathological types: hyalin-vascular, plasma-cell and mixed. We report three cases of the Castleman's disease (hyaline-vascular type) in three female patients with unilateral swelling of the neck. None of the patients developed any local or distant recurrence in postoperative follow-up.Öğe Ectopic bone formation in thyroid gland: report of sixteen cases and comprehensive literature review(Verduci Publisher, 2023) Sogutcu, N.; Akbulut, S.; Sari, A.; Yavuz, R.; Yagmur, Y.; Colak, C.- OBJECTIVE: This study aimed to analyze the outcomes of patients with ectopic bone formation (EBF) diagnosed in thyroidecto-my specimen.PATIENTS AND METHODS: We retrospec-tively analyzed the data of 16 patients who un-derwent thyroidectomy between February 2009 and June 2018 and whose pathology examina-tion diagnosed EBF. RESULTS: Fourteen patients underwent bilat-eral total thyroidectomy (BTT), one patient re-quired BTT with central lymph node dissection, and one patient was subjected to BTT with func-tional lymph node dissection. On histopatholog-ical examination, left lobe EBF was diagnosed in four patients; left lobe EBF with bilateral pap-illary thyroid carcinoma (PTC) in two; left lobe EBF with left lobe PTC in one; left lobe EBF with left follicular adenoma in one; left lobe EBF with right lobe papillary thyroid microcarcinoma in one; bilateral EBF in one; right lobe EBF with ex-tramedullary hematopoiesis in one; right lobe EBF in three; right lobe EBF with right lobe med-ullary thyroid carcinoma in one, and right lobe EBF with bilateral lymphocytic thyroiditis in one. One of the five patients who underwent bone marrow biopsy was diagnosed with myelopro-liferative dysplasia, and another with polycythe-mia vera. Three patients were treated medically for anemia because no other pathological find-ings could be observed.CONCLUSIONS: There is a lack of literature data about the clinical significance of EBF in the thyroid gland in cases with no concomitant he-matological diseases. People who have been di-agnosed with EBF in the thyroid gland should be checked for hematological diseases.Öğe The effect of different suture materials on the safety of colon anastomosis in an experimental peritonitis model(Verduci Publisher, 2013) Arikanoglu, Z.; Cetinkaya, Z.; Akbulut, S.; Ilhan, Y. S.; Aygen, E.; Basbug, M.; Ayten, R.BACKGROUND: The aim of this experimental study was to compare the safety of different suture materials in a left colonic anastomosis in the presence of peritonitis. MATERIALS AND METHODS: Twenty-one male Wistar albino rats were randomly divided into three groups. First, left colonic injuries were created in all groups for the peritonitis model. After 24 hours, coated polyglactin 910 and silk suture were used in Group I rats, polydioxanone and silk suture were used in Group II rats, and coated polyglactin 910 plus antibacterial suture and silk suture were used in Group III rats during colonic anastomosis. Tissue hydroxyproline, anastomotic bursting pressure, and histopathologic findings on the anastomosis line were evaluated on the 10th postoperative day by performing a relaparatomy. RESULTS: The mean bursting pressure values were 198 +/- 11.37, 220 +/- 17.7, and 244 +/- 9.52 in Groups I, II, and III, respectively (Group I vs. II, p < 0.035; I vs III, p < 0.002; and II vs III, p < 0.021). The mean hydroxyproline levels were 1.21 +/- 0.58, 1.47 +/- 0.44, and 2.11 +/- 0.32 in Groups I, II, and III, respectively (Group I vs II, p < 0.338; I vs III, p < 0.011; and II vs III, p < 0.025). When histopathologic findings of the groups were compared, the healing score of the intestinal tissue was higher in Group III than in Group I (p < 0.015), whereas there were no statistically significant differences among Groups I vs II and II vs III (p < 0.081 and p < 0.095, respectively). CONCLUSION: Antibacterial suture usage increased anastomosis safety in the presence of peritonitis in resection and primary anastomosis.Öğe A familial tendency for developing inguinal hernias: study of a single family(Springer, 2010) Akbulut, S.; Cakabay, B.; Sezgin, A.Inguinal hernias are the most common abdominal wall rupture, and the predisposing factors to hernia formation include a familial tendency, connective tissue and lung diseases, smoking and prostatism. The aim of this study is to discuss the familial tendency for hernia in 5 members of a family of 11 people. To our knowledge, no other large family with inguinal hernias has been reported in the English literature. This study presents the surgical procedures and follow-up results of right inguinal hernias seen in 5 of 11 members from one family. Age, sex, body mass index (BMI), biochemical parameters, type of hernia and surgical procedure, and follow-up results were evaluated retrospectively. This study included five patients (three males, two females) presenting with right direct inguinal hernias. The initial symptoms began at an average age of 18.2 years (range 15-22), and the mean BMI of the patients was 20.6 kg/m(2) (range 19.3-22.1). Three underwent hernia repairs with polypropylene surgical mesh and two with polyglactin-polypropylene composite mesh (Vypro II). The patients' blood vitamin C levels were lower than those of the other family members, while their 24-h urinary hydroxyproline levels were higher. The patients were followed for an average of 16.4 months (range 3-33 months). No complications developed during follow-up. The occurrence of the same type of hernia in more than one family member and the altered biochemical results indicate that the hernias may have resulted from a familial connective tissue disease. In patients with hernias, if a familial tendency is suspected, a detailed examination for connective tissue diseases may help to confirm the diagnosis.Öğe Scar Endometriosis in the Abdominal Wall: a Predictable Condition for Experienced Surgeons(Acta Medical Belgica, 2010) Akbulut, S.; Sevinc, M. Mahsuni; Bakir, S.; Cakabay, B.; Sezgin, A.Purpose : Endometriosis in surgical scars develops in 0.1% of those women who undergo Caesarean section or other obstetric surgery. Herein we analyse and discuss the clinico-pathological characteristics of 15 patients with scar endometriosis in the abdominal wall. Methods : Fifteen cases of scar endometriosis in the abdominal wall that were treated surgically in our department between 2003 and 2009 were examined retrospectively. Age, parity, complaint, medical or surgical history, pre/postoperative hormonotherapy, size of the mass, surgical procedure, follow-up and disease recurrence were analysed. Results : This retrospective study included 15 patients presenting with 17 postoperative abdominal wall masses. The mean age of the patients was 32.1 +/- 6.0 years (range, 23-48). Eleven of the patients had a painful mass that became bigger before menstruation, two had palpable masses only, and two were hospitalised because of a mass with persistent pain. The locations of the masses were as follows : eight were close to the right side and three were close to the left side; two were in the middle of the Pfanenstiel incision and two were in trocar tracts. The patients' surgical histories included Caesarean. section in thirteen, bilateral laparoscopic ovarian cyst excision in one, and laparoscopic appendectomy in one. Conclusions : if a patient presents with incision pain and a palpable mass after gynaecologic surgery, an incisional endometrioma should be considered. Surgical excision and hormone therapy are effective treatment approaches in these patients.
