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Öğe Cis-platinum combination chemotherapy during pregnancy for mucinous cystadenocarcinoma of the ovary.: Case report(S O G Canada Inc, 1999) Bayhan, G; Aban, M; Yayla, M; Gül, T; Yaldiz, M; Erden, AC[Abstract Not Available]Öğe CYP17 genetic polymorphism in patients with endometrial hyperplasia and cancer(Lippincott Williams & Wilkins, 2006) Aban, M; Arslan, M; Tok, E; Tekes, S; Budak, T; Altintas, AWe investigated the association of CYP17 gene polymorphism with the risk of having endometrial cancer and a well-known precursor of it, endometrial hyperplasia. Group A (control group) consisted of 35 patients who had histologically proven normal endometrium. Group B and C consisted of 18 and 30 patients who had endometrial hyperplasia with and without atypia, respectively. Group D consisted of 57 patients who had endometrial cancer. Venous blood samples were collected from patients in groups, and polymerase chain reaction was performed to determine the CYP17 gene polymorphism. Significant increase of A1/A1 and a decrease of A1/A2 genotype frequencies have been determined in patients with endometrial cancer and with atypical endometrial hyperplasia. No significant differences were found between groups in the frequency of A2/A2 genotype. There was no significant difference between the groups in the meaning of allele distributions. CYP17 polymorphism had correlation with endometrial atypia and cancer. Related effects of different types of CYP17 gene variants on the progression of hyperplastic endometrial cells into carcinoma should be evaluated in further studies. Progress in this area would help us modulate preventive treatments used in those actual high-risk group patients.Öğe Incomplete androgen insensitivity (testicular feminization) syndrome: Two case reports(Munksgaard Int Publ Ltd, 1996) Hakverdi, AU; Taner, CE; Aban, M; Vural, A; Gungoren, A; Yilmaz, N[Abstract Not Available]Öğe Prevalence, management and outcome in eclampsia(Wiley, 1996) Taner, CE; Hakverdi, AU; Aban, M; Erden, AC; Ozelbaykal, UObjective: To review the management of eclampsia in our institution. Method:The prevalence, management and outcome of women with eclampsia over a period of 8 years were reviewed at our referral medical center. There were 444 patients with eclampsia among 5757 deliveries (1 in 12.96 deliveries or 7.71% of deliveries). Most of the cases were uneducated and had received no antenatal care. One hundred eighty-one cases were nulliparous (40.77%). High parities of more than five were observed in 27.93% of cases. A standard magnesium sulfate regimen, similar to Prichard's intramuscular regimen, was used. Results: Magnesium sulfate effectively controlled the convulsions. The incidence of abdominal delivery among 397 cases with ante- and intrapartum eclampsia was 50.12%. Perinatal mortality was very high (591.47%0) for all cases. Maternal complications were serious and led to maternal death in 42 women (9.46%). Conclusion: Eclampsia is still a serious obstetric complication particularly in uneducated women who do not receive antenatal care.