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    Eosinophilia and related hematological disorders: Review
    (Turkiye Klinikleri, 2007) Altintaş A.; Özmen Ş.; Ayyildiz O.
    Eosinophilia is defined by an eosinophile count of >600/mm3; it may be primary or secondary due to the underlying cause. End-organ damage may develop in familial form as well as primary or secondary eosinophilia and it may also develop regardless of a specific cause in severe or mild eosinophilia;. Recently, the pathogenesis of clonal hypereosinophilia is well recognized and different variants are defined. Copyright © 2007 by Türkiye Klinikleri.
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    Microchimerism, a dilemma in current medicine
    (2006) Özmen Ş.; Daniş R.; Altintaş A.; Bayan K.; Yilmaz Ş.
    Microchimerism refers to presence of a small number of cells, or DNA of one individual harbored in another individual. Many studies indicate that cell trafficking occurs between the fetus and mother during pregnancy and between others after organ transplantation or blood transfusions. These cells or DHA can persist in recipient's blood or tissues for decades, creating a state of physiologic microchimetism. In several recent studies, microchimerism has been shown to have potential roles in pathogenesis of different diseases. However, due to the fact that microchimerism has also been found in healthy individuals and in organs affected by non-autoimmune conditions, an alternative hypothesis has been suggested in which microchimeiic cells are associated with the healing process of a tissue injury as opposed to causing disease. As a conclusion of this review of recent studies, we can say that microchimerism studies yielded more questions than answers.