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  • Küçük Resim
    Öğe
    The COVID-19 from neurological overview
    (Turkish Neurosurgical Society, 2020) Acar, Türkan Atılgan; Demirel, Esra Acıman; Afşar, Nazire; Akçal, Aylin; Demir, Gülşen Akman; Alagöz, Aybala Neslihan; Mengi, Tuğçe Angın; Arsava, Ethem Murat; Ayta, Semih; Bebek, Nerses; Bilgiç, Başar Gar; Boz, Cavit; Çakar, Arman; Çelebisoy, Neşe; Çevik, Mehmet Uǧur; Delen, Firuze; Tekçe, Hacer Durmuş; Ekmekçi, Hakan Ahmet; Elmal, Ayşe Deniz; Erdinç, Oǧuz Osman; Erdoǧan, Füsun Ferda; Eren, Fettah; Ergün, Ufuk; Parman, Yeşim Gülşen; Gümüş, Haluk; Algn, Demet İlhan; Karabudak, Rana; Karada̧s, Ömer; Yıldız, Özlem Kayım; Koç, Emine Rabia; Adapnar, Demet Özbabalk; Özdemir, Atilla Özcan; Öztürk, Şerefnur; Kocaman, Ayşe Saǧduyu; Sahin, Sevki; Topçuoğlu, Esen Saka; Şener, Özden; Tezer, Fadime İrsel; Toğrol, Rıfat Erdem; Tokçaer, Ayşe Bora; Topçuoǧlu, Mehmet Akif; Tuncer, Neşe; Uca, Ali Ulvi; Uluç, K.; Yaka, Erdem; Yön, Mehmet İlker
    Since December 2019, the disease caused by a new type of coronavirus called “New Coronavirus Disease (COVID-19)” has spread rapidly from Wuhan to other provinces of the Republic of China, and then to the entire world (1). With this pandemic around the world and in Turkey, very strong and shocking changes occurred in the flow of life, lifestyle, habits, education, politics, and the economy. Many issues related to COVID-19 have been discussed in the media, mostly new faces, new opinions, new expressions, mostly of scientists and physicians who have rarely been seen before have started to appear in media. With this fast-developing situation threatening the existence of all humanity, the perception of life, today and the future, has differentiated, and death has been considered more than ever before. In this process, new terms and concepts, which have never been used before or used very little, have started to be used frequently
  • Küçük Resim
    Öğe
    Impact of neutrophil-to-lymphocyte ratio on stroke severity and clinical outcome in anterior circulation large vessel occlusion stroke
    (Mdpi, 2024) Memiş, Zülfikar; Gürkaş, Erdem; Özdemir, Atilla Özcan; Acar, Bilgehan Atılgan; Öğün, Muhammed Nur; Aytaç, Emrah; Akpınar, Çetin Kürşad; Akıl, Eşref
    Background: The prognostic value of the neutrophil-lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates the relationship between admission NLR, stroke severity and 90-day outcomes in patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. Methods: A retrospective multicenter study was conducted with 1082 patients treated with mechanical thrombectomy for acute ischemic stroke. The relationship between admission NLR, baseline National Institutes of Health Stroke Scale (NIHSS), 24 h NIHSS and 90-day modified Rankin Scale (mRS) outcomes was analyzed using logistic regression. Results: Admission NLR correlated weakly but significantly with both baseline (p = 0.018) and 24 h (p = 0.005) NIHSS scores, reflecting stroke severity. However, multivariate analysis showed that higher 24 h NIHSS scores (OR 0.831, p = 0.000) and prolonged puncture-to-recanalization times (OR 0.981, p = 0.000) were independent predictors of poor 90-day outcomes, whereas NLR was not (p = 0.557). Conclusions: Admission NLR is associated with stroke severity but does not independently predict clinical outcomes at 90 days in patients achieving early and successful revascularization. These findings underscore the critical role of inflammation in the acute phase of stroke but suggest that its prognostic value for long-term outcomes is limited in this context.
  • [ X ]
    Öğe
    İNME KLİNİK PRATİĞİNDE NOAK KULLANIMI: TÜRK BEYİN DAMAR HASTALIKLARI DERNEĞİ UZMAN GÖRÜŞÜ
    (2020) Ünal, Ali; Eren, Alper; Yıldız, Özlem Kayım; Yaka, Erdem; Öztürk, Vesile; Özdemir, Atilla Özcan; Arsava, Ethem Murat
    Non-vitamin K oral antikoagülanların (NOAK) atrial fibrilasyonda inmenin önlenmesi amacıyla on yılı aşan bir süredir başarı ile kullanıldığı açıktır. Varfarine göre belirgin derecede az kanamaya yol açmaları ve inmeyi de eşit veya daha fazla oranda önleyebilmeleri yanı sıra kolay kullanım özellikleri primer proflakside atrial fibrilasyona bağlı inmeyi azaltma konusunda öne çıkmaktadır. Bunlar aynı zamanda genel inme prevalansının azalması anlamına gelmektedir. Yani AF nedenli inmenin engellenmesi toplum sağlığı için çağdaş bir gereklilik olarak algılanmalıdır. İnme klinik pratiğinde kardiyoloji uzmanları ile birlikte bu bağlamda çaba sarf eden nöroloji uzmanları için Türk Beyin Damar Hastalıkları Derneği bu uzman görüşünü hazırladı. Görüşler NOAK grubu ilaçların kullanımında sıkça karşılaşılan sorunlar ve bu problemler için güncel çözüm önerilerini içermektedir.