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    Anti-tuberculosis drug resistance in southeast of turkey
    (Acta Medica Mediterranea, 2013) Dal T.; Özcan N.; Tekin R.; Tekin A.; Çelen M.K.; Özekinci T.
    Objective: Tuberculosis is a globally prevalent life-threatening infectious disease. In this study we aimed to evaluate antibiotic suscebtibility rates of Mycobacterium tuberculosis complex strains. Materials and methods: A total of 150 culture-positive samples were included in. Among culture positive samples 86 were Mycobacterium tuberculosis complex and 64 were non-tuberculous mycobacterium. Of Mycobacterium tuberculosis complex isolated samples 45 were Ziehl-Neelsen positive. Of 64 non-tuberculous mycobacterium isolated samples 15 were Ziehl-Neelsen positive. Mean age of the patients with tuberculosis was 37.74±20.53 and non-tuberculous mycobacterium isolated patients was 46.80±23.32. Antibiotic susceptibility testing was performed for the four first-line anti-tuberculosis drugs by BACTEC MGIT-960 instrument (Becton Dickinson). Of M. tuberculosis strains 41 % was resistant to at least one or more of the drugs (isoniasid 27.9%, ethambutol 8.13%, streptomycin 12.79 %, rifampicine 9.3 %). Of the strains 5.8 % was resistant to two, 3.4 % to three and 3.4 % to four drugs. Conclusion: Mycobacterium tuberculosis complex and drug resistance of this microorganism continued to be a problem for our country and non-tuberculous mycobacterium species may become a problem in the future. We thought that a strong and costeffective tuberculosis control programme contributes to reduce the incidence of drug resistance in the community.
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    Seroprevalence of hepatitis b and tetanus among ezidian (Yazidi) women fleeing war
    (Bulgarian Society for Microbiology (Union of Scientists in Bulgaria), 2018) Özcan N.; Bulut Z.K.; Evinç E.; Yiğitalp G.; Özekinci T.; Ceylan A.
    Women suffer much from wars and forced migrations. In 2014, Ezidians (Yazidis) living in Iraq migrated to Syria and then to Turkey due to civil war. Tetanus is a bacterial infection caused by Clostridium tetani spores getting into the body. Hepatitis B is an infection caused by the hepatitis B virus. Both hepatitis B and tetanus are vaccine-preventable diseases. We aimed to evaluate the seroprevalence of tetanus and hepatitis B among Yazidi women who had fled to our country and have been living in a tent city. This study was conducted in Diyarbakır province, located in Southeastern Turkey, between July 2015 and February 2016. A total of 245 Yazidi women aged between 15 and 49 years, living in a tent city, were included. HBsAg, anti-HBs and anti-HBcIgG were studied by ELISA method with Cobas e 601 (Roche Diagnostics, Switzerland) system autoanalyzer. Antibodies to tetanus toxin were tested by ELISA method with the Virotech ELISA tetanus (Virotech, Germany). Of the 245 women, 38 (15.5%) had vaccine-induced immunity, while 11 (4.5%) had antibodies against hepatitis B due to previous exposure. Two women (0.8%) had isolated anti-HBcIgG positivity. Among 245 women, 96 (39.2%) had anti-tetanus antibodies. This population was notably susceptible to both tetanus and hepatitis B. Vaccination of this sensitive population was important for the well-being of the women, their spouses and children to be born. © 2018, Bulgarian Society for Microbiology (Union of Scientists in Bulgaria). All rights reserved.
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    Öğe
    Three cases of chronic suppurative otitis media (CSOM) caused by kerstersia gyiorum and a review of the literature
    (EDIMES Edizioni Medico Scientifiche, 2018) Özcan N.; Saat N.; Baylan M.Y.; Akpolat N.; Atmaca S.; Gül K.
    New identification techniques such as gene sequencing and mass spectrometry have increased the incidence of novel agents such as Kerstersia gyiorum. As a new member of the Alcaligenaceae family, K. gyiorum was isolated from wounds, respiratory tract, urine specimens and most frequently from chronic suppurative otitis media (CSOM). We isolated three K. gyiorum strains from three CSOM cases over a one-year period. The strains were analyzed by mass spectrometry and identified by Bruker Biotyper 3.1 (Bruker Daltonics, USA). The cases were young patients without chronic diseases and immuno-deficiencies. Two strains were resistant to ciprofloxacin. © 2018, EDIMES Edizioni Medico Scientifiche. All rights reserved.