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Öğe Assessment of sharps penetrating injury, mucosal exposure and compliance with standard precautions of health workers at a University Hospital in Turkey(NLM (Medline), 2023) Sarı, Hıdır; Dayan, Saim; Balkan, Hüsna; Çiçek, Yeliz; Özel, MehmetObjectives: To evaluate the compliance with standard precautions in healthcare workers who experienced a sharps penetrating injury or mucosal exposure using the compliance with Standard Precautions Scale, Turkish version. Methods: This descriptive cross-sectional study was conducted in a tertiary hospital. The occupational health and safety unit records of healthcare workers who were injured by a sharps penetrating injury or experienced mucosal exposure between January 2018 and July 2020 were examined. Compliance with the Standard Precautions Scale was assessed by having participants answer a questionnaire. Results: Of the 100 participants, 59% were men. Of all healthcare workers in the university hospital, 4.5% (n=100) were injured by sharps penetrating injuries or mucosal exposure. Of the participants, 95% were wounded by a sharps penetrating injury and 5% had mucosal exposure. The mean Compliance with Standard Precautions Scale score of participants with a sharps penetrating injury was 16.36±2.39 and with mucosal exposure was 16.80±3.03. There was no significant difference between the mean Compliance with Standard Precautions Scale scores of the sharps penetrating injury and mucosal exposure groups regardless of training on occupational health and safety (p=0.794). Conclusion: In conclusion, the frequency of a sharps penetrating injury and mucosal exposure in healthcare workers was similar to the literature. The compliance level of the healthcare workers measured with the Compliance with Standard Precautions Scale was high.Öğe Bruselloz tanılı hastaların klinik, laboratuvar ve epidemiyolojik özelliklerinin incelenmesi(Dicle Üniversitesi, Tıp Fakültesi, 2021) Çiçek, Yeliz; Dayan, SaimOcak 2017 Aralık 2018 Tarihleri Arasında Dicle Üniversitesi Tıp Fakültesi Hastanesinde İzlenen Bruselloz Tanılı Yetişkin Hastaların Retrospektif Olarak Değerlendirilmesi Amaç: Bu araştırmada Dicle Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları servis ve/veya polikliniğinde izlenen, bruselloz tanısı almış hastaların; demografik özellikleri, klinik, laboratuvar, radyolojik bulguları ve uygulanan tedavi rejimlerinin değerlendirilmesinin yanısıra brusella capture titresi ile kan kültür pozitifliği arasındaki ilişkinin de değerlendirilmesi amaçlanmıştır. Ayrıca hastaların müracaat ettikleri branşlar ile tanı sonrası hastalık bildiriminin yapılma oranları irdelenmiştir. Gereç ve Yöntemler: Ocak 2017-Aralık 2018 tarihleri arasında Dicle Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları Kliniği ve/veya Polikliniği'nde izlenen bruselloz tanısı almış 214 hastanın dosyaları retrospektif olarak incelendi. Çalışmaya alınan 118 hastanın demografik ve klinik özellikleri kaydedildi. Hastaların rose bengal, brusella capture testleri ve hemokültürleri Dicle Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Laboratuvarında diğer laboratuvar testleri ise Merkez Laboratuvarında çalışıldı. Bulgular: Hastaların yaş ortalaması 39,54±17,123 olup, hastaların %50'si erkek %50'si idi. Hastaların %58,5'i kırsal alanda yaşarken; %41,5'i kent merkezinde yaşıyordu. Başvuru anında en sık iki şikâyetin %89 ile ateş, %73,7 ile kemik-eklem ağrısı olduğu tespit edilmiştir. Hastalarının tanı anındaki en sık iki fizik muayene bulgusu %89 ile ateş %73,7 ile kemik ve eklemlerde hassasiyet olarak tespit edilmiştir. Eritrosit sedimentasyon hızı yüksekliği hastaların %29,6'sında, CRP yüksekliği ise hastaların %55,9'unda tespit edildi. Tanı anında en sık iki hematolojik bulgu: %45,8 ile anemi %26,3 ile lenfomonositoz olarak saptandı. En sık görülen iki tutulum %31,4 ile sakroileit, %25,4 ile splenomegali olarak saptandı. Hastaların %59,3'ünde hastalık bildiriminin yapıldığı, enfeksiyon hastalıkları kliniğinde bildirim oranının %64,7 olduğu, enfeksiyon dışı kliniklerde ise bildirimin %25'te kaldığı saptandı. Hastaların %86,4'ünün enfeksiyon hastalıkları kliniğine başvurduğu saptandı. Hastaların enfeksiyon dışı kliniklere başvuruları incelendiğinde hastaların %50'sinin dahiliye, %31,25'inin ise Fizik Tedavi-Rehabilitasyon, %6,25 Üroloji, %6,25 Kadın doğum, %6,25 Psikiyatri kliniğine başvurduğu saptanmıştır. Bruselloz nedeniyle takipli 118 hastanın 56'sından kan kültürü alındığı bunlardan 30'unda üreme olduğu saptanmış olup; üreyen mikroorganizmaların tamamı B. Melitensis idi. Brusella capture titresi ?1280 olan hastaların %62,5'inde; <1280 olan hastaların %31,25'inde kan kültüründe üreme olduğu saptanmıştır. Sonuç: Bruselloza bağlı anemi, lökopeni ve trombositopeni gibi hematolojik bulguları olan hastalarda sakroileit ve splenomegali gelişme oranında istatiksel olarak anlamlı fark bulunmuştır (p<0.05). Hastaların brusella capture titresi yükseldikçe (1/320 den 1/5120'ye doğru gidildikçe) kan kültüründe brusella bakterisini izole etme oranında istatiksel olarak anlamlı bir fark saptandı.(p<0.05) Brusella açısından endemik kabul edilen ülkemizde özellikle kırsal kesimden, ateş ve kemik eklem ağrısı ile gelen hastaların brusella açısından ayrıntılı öyküsünün alınması ile erken tanı konularak olası komplikasyonların önünde geçilmesi hedeflenmelidir. Bu amaçla enfeksiyon hastalıkları alanında uzman olmayan hekimlerin de tanı, tedavi ve takip açısından bilgi ve becerilerinin yeterli düzeyde olabilmesi için gerekli farkındalık oluşturulmalı ve periyodik eğitimler verilmelidir.Öğe Clinical and epidemiological evaluation of influenza and SARS-CoV-2 coinfected cases(Journal of Infection in Developing Countries, 2024) Çiçek, Yeliz; Sarı, Hıdır; Yetkin, Duygu İmre; Özel, MehmetIntroduction: Coinfection of COVID-19 with influenza pathogens, may complicate the diagnosis, treatment, and prognosis, which is a new concern. This study aims to evaluate COVID-19 and influenza coinfected cases during the flu season, while the SARS-CoV-2 pandemic continues. Methodology: The study was conducted between November 2021 and January 2022. A total of 1987 (1752 outpatients, 235 inpatients) patients were included, and 44 simultaneous COVID-19 and influenza laboratory-confirmed diagnoses. Results: During the study period, 1553 patients were diagnosed with COVID-19, 390 influenza, and 44 were diagnosed with coinfection. The incidence of coinfected cases was 2.2% (n = 44) in all patients, When coinfected cases were examined, there was a statistically significant difference between the disease duration in the inpatients (19.86 ± 10.78 days) and the disease duration in the outpatients (7.63 ± 2.25 days) (p < 0.05). 31.8% (n = 14) of coinfected cases were hospitalized, and the mortality rate was 50.0% (n = 7) in hospitalized patients. Conclusions: Coinfection with SARS-CoV-2 and Influenza was not uncommon. Data on coinfected cases are limited in the literature. The coinfection with SARS-CoV-2 and influenza A should be considered in patients with complaints such as fever, myalgia, weakness, shortness of breath, and cough during the flu season. Using the diagnostic test showing two diseases in a single sample may contribute to protecting patient and community health in follow-up and treatment.Öğe Clinical, laboratory, and epidemiological characteristics of patients diagnosed with brucellosis: A comprehensive analysis(Dicle Üniversitesi Tıp Fakültesi, 2023) Çiçek, Yeliz; Özcan, Nida; Demir, Yakup; Dayan, SaimIntroduction: This study aims to evaluate the demographic characteristics, clinical manifestations, laboratory findings, radiological features, and the relationship between brucella capture titers and blood culture positivity in patients followed up due to brucellosis. Methods: The medical records of 214 patients diagnosed with brucellosis, who were followed up at the infectious diseases clinic and/or outpatient clinic between January 2017 and December 2018, were retrospectively reviewed. Demographic and clinical characteristics of 118 included patients were recorded. Brucella capture tests and blood cultures were processed at bacteriology department of Dicle University Hospital Laboratory. Results: The mean age of the patients was 39.54±17.123 years. Fifty percent of the patients were male and 58.5% of the patients resided in rural areas. The most common complaints at presentation were fever (89%) and bone-joint pain (73.7%). The most frequent physical examination findings were fever (89%) and tenderness in bones and joints (73.7%). Elevated erythrocyte sedimentation rate was observed in 29.6% of patients, while elevated c-reactive protein levels were seen in 55.9% of the patients. The two most common hematological findings at the time of diagnosis were anemia with 45.8% and lymphomonocytosis with 26.3%. A statistically significant disparity was observed in the incidence of complications among patients displaying hematological manifestations, including anemia, leukopenia, and thrombocytopenia, associated with brucellosis (p<0.05). The most commonly encountered organ involvements were sacroiliitis, with a prevalence of 31.4%, and splenomegaly, noted in 25.4% of cases. Among the patient cohort, disease reporting was documented in 59.3% of instances. The reporting rate was notably higher at the infectious diseases clinic, accounting for 64.7% of cases, whereas non-infectious clinics exhibited a lower reporting rate of 25%. Blood cultures were taken from 56 of 118 patients followed up due to brucellosis and growth was detected in 30 of them. All of the microorganisms grown were determined to be B. Melitensis. Notably, 62.5% of patients with a brucella capture titer ≥1/ 1280 and 31.25% of those with titers <1/ 1280 exhibited growth in blood cultures. There was a statistically significant correlation between the elevation of brucella capture titers among patients, ranging from 1/320 to 1/5120, and an increased likelihood of detecting brucella bacteria through blood culture (p<0.05). Conclusion: This study revealed a correlation between higher brucella capture titers and blood culture positivity. In addition, markers such as anemia, leukopenia, and thrombocytopenia were associated with an increased risk of complications, emphasizing their importance as prognostic indicators.Öğe Comparison of thorax computed tomography based body composition parameters between COVID-19 positive and negative patients: A cross-sectional study(Türkiye Klinikleri, 2023) Yetkin, Duygu İmre; Çiçek, Yeliz; Sarı, Hıdır; Özmen, Cihan AkgülObjective: To compare body fat-muscle and visceral obesity indices that can be measured with thorax computed tomography (CT) between reverse transcriptase-polymerase chain reaction (RT-PCR) positive and negative patients. Material and Methods: This ret-rospective, comparative study included 141 PCR (+) and 150 PCR (-) patients who applied to our hospital with flu-like symptoms without having the comorbid diseases and undergone thoracic CT between April 1, 2020-July 1, 2020. For the each patient, the ratio of thoracic subcutaneous adipose tissue thickness to pectoralis major muscle thickness (TSAT/PMJ), epicardial adipose tissue thickness (EAT), liver density (LD), abdominal subcutaneous adipose tissue thickness to psoas major muscle thickness ratio (ASAT/ PSM), subcutaneous abdominal adipose tissue thickness to erector spinae muscle thickness ratio (ASAT/ESM) was measured. The comparison was made between the subgroups in terms of age, gender, and measured parameters. Results: Statistically significant difference was found between PCR (+) and (-) individuals in terms of EAT mean (p<0.05). TSAT/PMJ, ASAT/PSM and ASAT/ESM ratios were higher in women (p <0.05). The mean EAT in men was increased in the PCR (+) group (p<0.05). In PCR (+) group, LD decreased, EAT increased with increasing age (p[removed]0.05) in terms of TSAT/PMJ, ASAT/PSM, LD, ASAT/ESM. Conclusion: Higher EAT values can increase the risk of getting coronavirus disease-2019 (COVID-19) infection. Peripheral fat-muscle indices don’t increase the risk of contracting COVID-19 infection.
