Hypovolemic shock as an initial presentation of pediatric systemic lupus erythematosus
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CitationEce, A., Boşnak, M., Gürkan, F., Davutoğlu, M. ve Haspolat, Y. K. (2005). Hypovolemic shock as an initial presentation of pediatric systemic lupus erythematosus. Pediatrics International, 47(3), 348-351.
Most children with systemic lupus erythematosus (SLE) initially present with non-specific symptoms of fever, anorexia, weight loss and malaise; hypovolemic shock has never been described as onset of the disease1. When circulating lupus anticoagulant (LA) or immune thrombocytopenia lead to hemorrhage in patients with SLE, supportive medical interventions alone might not improve the situation. In these life-threatening emergencies, morbidity and mortality may be high, despite adequate supportive measures, unless aggressive immunosuppressive treatment is instituted. We present a case of SLE with urogenital hemorrhage leading to shock and lethargy necessitating intensive care management in a pediatric patient with membranous nephropathy.