Browsing by Author "Boğa, Mehmet"
Now showing items 1-12 of 12
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Anticholinesterase and antioxidant activities of novel heterocyclic Schiff base derivatives containing an aryl sulfonate moiety
Kamalı, Ayfer; Çakmak, Reşit; Boğa, Mehmet (Wiley-V C H Verlag GMBH, 2022)In this research, nine novel heterocyclic Schiff base derivatives (10-18) bearing an aryl sulfonate moiety were designed, synthesized for the first time, and characterized. Then, their inhibitory effects on acetyl- and ... -
Cytotoxic and apoptotic effects of Hypericum androsaemum on prostate adenocarcinoma (PC-3) and hepatocellular carcinoma (Hep G2) cell lines with identification of secondary metabolites by LC-HRMS
Bektaş, Nurdan Yazıcı; Ersoy, Ezgi; Boğa, Mehmet; Boran, Tuğçe; Çınar, Ercan; Özhan, Gül; Gören, Ahmet Ceyhan; Özkan, Esra Eroğlu (Scientific Technical Research Council Turkey-TUBITAK, 2021)The study aims to determine the secondary metabolites of Hypericum androsaemum L. extracts by liquid chromatography-high resolution mass spectrometry (LC-HRMS), and investigate the antioxidant and cytotoxic activities of ... -
Design, synthesis and biological evaluation of 1,3-diaryltriazene-substituted sulfonamides as antioxidant, acetylcholinesterase and butyrylcholinesterase inhibitors
Akocak, Süleyman; Boğa, Mehmet; Lolak, Nabih; Tuneğ, Muhammed; Sanku, Rajesh Kishore Kumar (Turkish Chemical Society, 2019)1,3-diaryltriazenes are one of the most useful and important linkers for many pharmaceutical applications. Therefore, in the current work, a series of 1,3-diaryltriazene sulfonamides 4(a-k) were synthesized by reacting ... -
Di-, and triterpenoids isolation and LC-MS analysis of salvia marashica extracts with bioactivity studies
Aydın, Sibel Kıran; Ertaş, Abdulselam; Boğa, Mehmet; Erol, Ebru; Toraman, Gülbahar O. Alim; Saygı, Tuba Kusman; Halfon, Belkıs; Topçu, Gülaçtı (ACG Publications, 2021)Abstract: In this study, dichloromethane, acetone, and methanol extracts of the aerial parts of the Salvia marashica plant which is an endemic species to Anatolia, were investigated. The total phenolic amounts of ... -
Heterocyclic Schiff base derivatives containing pyrazolone moiety: Synthesis, characterization, and in vitro biological studies
Çınar, Ercan; Başaran, Eyüp; Erdoğan, Ömer; Çakmak, Reşit; Boğa, Mehmet; Çevik, Özge (Wiley, 2021)In this study, some pyrazolone-based Schiff base derivatives 2a-e (except 2a)were synthesized for the first time and structurally illuminated by some spec-troscopic techniques (1H,13C NMR, FT-IR) and elemental analysis. ... -
In Silico studies and DNA cleavage, antioxidant, acetylcholinesterase, and butyrylcholinesterase activity evaluation of bis-histamine schiff bases and bis-spinaceamine substituted derivatives
Lolak, Nebih; Boğa, Mehmet; Sönmez, Görkem Deniz; Tuneğ, Muhammed; Doğan, Aslınur; Akocak, Süleyman (Springer, 2022)In this work, a series of seven bis-histamine Schiff bases (H1-H4) and bis-spinaceamine substituted derivatives (SPH1, SPH2, and SPH4) were successfully re-synthesized to evaluate their antioxidant properties by several ... -
Kekik olarak kullanılan Thymus fallax ve thymus kotschyanus var. kotschyanus bitkilerinin kimyasal i̇çerikleri, antimikrobiyal, antioksidan ve antialzheimer aktivitelerinin belirlenmesi
Tuncay, Eyyüp (Dicle Üniversitesi, Sağlık Bilimleri Enstitüsü, 2019)Amaç: Thymus cinsi genel olarak yemeklere tat ve koku verici amaçla kullanılır ve tıbbi ve ekonomik önemi olan bitkiler sınıfındandır. Birçok biyolojik ve farmakolojik aktivitesi bilinen Thymus cinsine ait T. fallax ve T. ... -
Phytochemical analysis and antioxidant and anticholinesterase activities of Pulicaria dysenterica from Turkey
Boğa, Mehmet; Ertaş, Abdulselam; Yeşil, Yeter; Haşimi, Nesrin; Yılmaz, Mustafa Abdullah; Özaslan, Cumali (Dicle Üniversitesi Fen Bilimleri Estitüsü, 2014)[Özet Yok] -
Salvia pseudeuphratica bitkisinin sekonder metabolitlerinin saflaştırılması, antioksidan ve antialzheimer aktivitelerinin belirlenmesi ve LC-MS/MS ve GC-MS ile kimyasal i̇çeriklerinin i̇ncelenmesi
Tuncay, Evin Aygün (Dicle Üniversitesi, Sağlık Bilimleri Enstitüsü, 2019)Amaç:Ülkemiz birçok iklim koşullarını barındırması nedeniyle bitkilerin çeşitliği açısından zengindir. Dünya genelinde çay olarak tüketilen bitkiler ve baharat dışsatımlamasındasöz sahibi ülkelerden biri olmasının yanısıra ... -
Terpenoid and fatty acid profiling along with anti-tyrosinase and anti-urease potentials of scorzonera pygmaea sibth. & sm. an endemic plant of Turkey
Şahin, Hasan; Boğa, Mehmet; Sarı, Aynur (Wiley-V C H Verlag GMBH, 2022)Petroleum ether (PE), chloroform (CH), ethyl acetate (EA) and butanol (BU) fractions were obtained from ethanol extracts of the roots (SPR) and the above ground (SPH) parts of S. pygmaea. PE fractions were evaluated by ... -
Teucrium parviflorum ve Teucrium polium bitkilerinin kimyasal ve biyolojik aktivite yönünden incelenmesi
Suvari, Goncagül (Dicle Üniversitesi, Sağlık Bilimleri Enstitüsü, 2019)Amaç: Literatürde antioksidan özelliklerine atıfta bulunulan Lamiaceae familyası üyeleri T. parviflorum ve T. polium bitkilerinin etanol ekstrelerinin toplam fenolik ve flavonoid miktarları ile antioksidan ve antikolinesteraz ... -
Volatile and phenolic profiling of a traditional medicinal plant, Hypericum empetrifolium with in vitro biological activities
Boğa, Mehmet; Ersoy, Ezgi; Özkan, Esra Eroğlu; Çınar, Ercan; Kara, Emel Mataracı; Cantürk, Yeter Yeşil; Zengin, Gökhan (Elsevier Ireland LTD, 2021)Ethnopharmacological relevance: Hypericum empetrifolium Willd is a member of the Hypericaceae family, mainly known in southern Greece, and western Turkey. Being a centuries-old medicinal plant, the aerial parts of the plant ...
