Browsing by Author "Bingül, Murat"
Now showing items 1-4 of 4
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The Hemetsberger reaction: A new approach to the synthesis of novel dihydroindoloindole systems
Bingül, Murat; Kumar, Naresh; Black, David StC (Arkat Usa Inc, 2020)The Hemetsberger indole synthesis provides an alternative method for the preparation of dihydroindoloindole systems. Two novel examples, dimethyl 3,8-dihydroindolo[7,6-g]indole-2,7-dicarboxylate and dimethyl 1,6dihydroin ... -
Synthesis and characterisation of novel tricyclic and tetracyclic furoindoles: Biological evaluation as SAHA enhancer against neuroblastoma and breast cancer cells
Bingül, Murat; Arndt, Greg M.; Marshall, Glenn M.; St. Black, David C.C.; Cheung, Belamy; Kumar, Naresh Sampath (MDPI, 2021)The dihydropyranoindole structures were previously identified as promising scaffolds for improving the anti-cancer activity of histone deacetylase inhibitors. This work describes the synthesis of related furoindoles and ... -
Synthesis, characterization and biological evaluation of novel dihydropyranoindoles improving the anticancer effects of HDAC inhibitors
Bingül, Murat; Arndt, Greg M.; Marshall, Glenn M.; Cheung, Belamy; Kumar, Naresh Sampath; Black, David St Clair (MDPI AG, 2020)The dihydropyranoindole scaffold was identified as a promising target for improving the anti-cancer activity of HDAC inhibitors from the preliminary screening of a library of compounds. A suitable methodology has been ... -
Synthesis, reactivity and biological properties of methoxy-activated indoles
Şengül, İbrahim F.; Bingül, Murat; Kandemir, Hakan; Kumar, Naresh; Black, David StC. (Society Chimica Italiana, 2021)Indoles continue to play a central role in the development of new structures of chemical and biological interest. They are the source of numerous biologically active natural products by virtue of their derivation from ...
