Investigation of The Effects of Electromagnetic Fields on SerumParaoxonase (PON1)

Abstract

INTRODUCTION: The widespread use of electrical devices inthe society and being in close contact with these devices causeboth anxiety and affect public health. The aim of this study is toinvestigate whether high voltage induced electromagnetic fieldexposure on different days affects serum paraoxanase 1activity of rats. METHODS: The study included 24 adult male wistar albinorats, weighing 320 grams on average. They were randomlygrouped into 3 as n: 8. Group 1: Sham-control, Group 2: 26days High voltage (HV) and Group 3: 52 days HV. The rats inthe 26-day and 52-day experimental groups (Groups I, II)received electric and magnetic fields for 8 hours each day. RESULTS: We found a decrease in paraoxonase (PON1)activity in the 26- and 52-day high-voltage exposure groupcompared to the control group. A statistically significant(p=0.000) change was found between the groups. DISCUSSION AND CONCLUSION: :Our study suggests thatthe exposure to high voltage line may cause a reduction ofparaoxonase 1 activity. We've noticed that short-termexposures, compared to long-term ones, may lead to lowerparaoxonase 1 activity. Therefore, our study also points to theimportance of further research in this regard.