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dc.contributor.authorGeneş, Dilek
dc.contributor.authorPekkolay, Zafer
dc.contributor.authorŞimşek, Mehmet
dc.contributor.authorSaraçoğlu, H.
dc.contributor.authorTurgut, M.
dc.contributor.authorTekeş, Selahattin
dc.contributor.authorTuzcu, Alpaslan Kemal
dc.date.accessioned2024-04-24T17:58:20Z
dc.date.available2024-04-24T17:58:20Z
dc.date.issued2023
dc.identifier.citationGeneş, D., Pekkolay, Z., Şimşek, M., Saraçoğlu, H., Turgut, M., Tekeş, S. ve diğerleri. (2023). Comparison of C-peptide levels in monogenic forms of diabetes with other types of diabetes: A single-center study. Acta Endocrinologica, 19(3), 281-285.
dc.identifier.issn1841-0987
dc.identifier.urihttps://doi.org/10.4183/aeb.2023.281
dc.identifier.urihttps://hdl.handle.net/11468/23843
dc.description.abstractObjective. This study aimed to evaluate the utility of C-peptide levels in the differentiation of monogenic forms of diabetes from type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in clinical practice. Subjects and Methods. A total of 104 patients aged >16 who visited the Dicle University’s Faculty of Medicine between April 2011 and December 2020 and were diagnosed with monogenic diabetes by genetic analysis or with T1DM and T2DM were randomly selected for retrospective evaluation. The C-peptide levels of these patients at the time of diagnosis of diabetes were compared. Results. Of the 104 patients, 24 (23%) were diagnosed with maturity-onset diabetes of the young (MODY), 40 (38.5%) with T1DM, and 40 (38.5%) with T2DM. Median C-peptide levels (ng/mL) (interquartile range) were 1.78 (1.24-2.88) in MODY group, 0.86 (0.34- 1.22) in T1DM group, and 2.38 (1.58-4.27) in T2DM group. Conclusions. There was a difference in C-peptide levels between MODY and T1DM groups but not between MODY and T2DM groups. As per clinical evaluations, although C-peptide levels of patients with MODY are similar to those of patients with T2DM patients, the possibility of C-peptide levels being similar to those required for T1DM diagnosis should also be considered.en_US
dc.language.isoenen_US
dc.publisherActa Endocrinologica Foundationen_US
dc.relation.ispartofActa Endocrinologicaen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-Peptideen_US
dc.subjectModyen_US
dc.subjectMonogenic diabetesen_US
dc.subjectType 1 diabetesen_US
dc.subjectType 2 diabetesen_US
dc.titleComparison of C-peptide levels in monogenic forms of diabetes with other types of diabetes: A single-center studyen_US
dc.typeArticleen_US
dc.identifier.volume19en_US
dc.identifier.issue3en_US
dc.identifier.startpage281en_US
dc.identifier.endpage285en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.scopus2-s2.0-85186431945en_US
dc.identifier.doi10.4183/aeb.2023.281
dc.identifier.scopusqualityQ4en_US
dc.indekslendigikaynakScopusen_US


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