Histopathological Evaluation of the Polyps with and without the Presence Cholesteatoma

Abstract

Objective: To determine if there were any differences between the histopathological structures of the polyps with or without cholesteatoma Materials and Methods: In our study, 41 patients underwent operation with complaints of chronic otitis media with polyp. The patients were divided into those who had cholesteatoma and those who did not, so that discriminatory features were identified. Chronic otitis media with polyp was associated with cholesteatoma in 21 patients. Cholesteatoma was not found in 20 patients with chronic otitis media with polyp. Specimens removed from the both of patients groups were evaluated and compared between the groups in according to histopathologic features. Results: We observed that specimens of polyps with cholesteatoma were comprised of keratinized masses, keratinized tissue layers, and abundant immature granulation tissue, whereas, specimens of the polyps without cholesteatoma consisted of copious glandular stroma bordered by smooth epithelium (p<0,05). Conclusion: Our study showed that histopathologic features of the polyps suggest the presence or absence of cholesteatoma.