dc.contributor.author | Ersoy, Ezgi | |
dc.contributor.author | Tanaman, Irmak | |
dc.contributor.author | Özkan, Esra Eroğlu | |
dc.contributor.author | Karahan, Selim | |
dc.contributor.author | Şahin, Hasan | |
dc.contributor.author | Çınar, Ercan | |
dc.contributor.author | Cantürk, Yeter Yeşil | |
dc.contributor.author | Kara, Emel Mataracı | |
dc.contributor.author | Zengin, Gökhan | |
dc.contributor.author | Boğa, Mehmet | |
dc.date.accessioned | 2023-08-04T07:46:23Z | |
dc.date.available | 2023-08-04T07:46:23Z | |
dc.date.issued | 2023 | en_US |
dc.identifier.citation | Ersoy, E., Tanaman, I., Özkan, E. E., Karahan, S., Şahin, H., Çınar, E. ve diğerleri. (2023). Phytochemical analysis of essential oils and the extracts of an ethnomedicinal plant, Teucrium multicaule collected from two different locations with focus on their important biological activities. South African Journal of Botany, (153), 124-135. | en_US |
dc.identifier.issn | 0254-6299 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0254629922006779 | |
dc.identifier.uri | https://hdl.handle.net/11468/12430 | |
dc.description.abstract | Teucrium species have been among the most commonly used traditional medicinal plants and they are
known to have extensive therapeutic applications. The main focus of this study, Teucrium multicaule is also
renowned for being an important medicinal and aromatic plant in Turkiye. Volatile profiling of the essential
oils was conducted by GC MS, phytochemical profiling of the ethanol extracts was carried out by LC HRMS,
antioxidant, anticholinesterase, antityrosinase, antiurease, antidiabetic, anticancer, and antimicrobial activities were revealed by different assays. Germacrene D was the most abundant compound in the essential oils
from Diyarbakir (TmuD) with 45.4%, and Batman (TmuB) with 54.7%. All extracts were found to be quite rich
in phytochemicals by LC HRMS, and herniarin, caffeic acid, naringenin, luteolin, scutellarein, hispidulin,
rhamnocitrin, penduletin, eupatilin, (-)-epigallocatechin gallate, hederagenin, and verbascoside were found
to be present in all extracts. T. multicaule roots extract from Diyarbakir (TmuRD) demonstrated the highest
radical scavenging, a-amylase inhibitory (59.82§0.36%), and antibutyrylcholinesterase activity (61.96§
1.72%), whereas T. multicaule aerial parts extract from Batman (TmuHB) exhibited the strongest antityrosinase (66.17§0.92%), antiurease (67.85§0.69%), and cytotoxic (54.76 § 1.57 mg/mL) activities. TmuRD also
showed significant antimicrobial activity against S. epidermidis with 156.2 mg/mL MIC value. As revealed by
this first detailed report on T. multicaule, the plant demonstrates various important biological activities
attributed to its rich phytochemicals, which also justifies its use in ethnomedicine. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.ispartof | South African Journal of Botany | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Teucrium multicaule | en_US |
dc.subject | LC-HRMS | en_US |
dc.subject | Enzyme inhibitory activity | en_US |
dc.subject | Cytotoxicity | en_US |
dc.subject | Traditional uses | en_US |
dc.title | Phytochemical analysis of essential oils and the extracts of an ethnomedicinal plant, Teucrium multicaule collected from two different locations with focus on their important biological activities | en_US |
dc.type | Article | en_US |
dc.identifier.issue | 153 | en_US |
dc.identifier.startpage | 124 | en_US |
dc.identifier.endpage | 135 | en_US |
dc.department | Dicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü | en_US |
dc.authorid | 0000-0002-6913-1952 | en_US |
dc.authorid | 0000-0002-1569-2535 | en_US |
dc.authorid | 0000-0001-5784-7091 | en_US |
dc.authorid | 0000-0002-8325-8116 | en_US |
dc.authorid | 0000-0003-0419-7798 | en_US |
dc.authorid | 0000-0002-4458-7881 | en_US |
dc.authorid | 0000-0002-4428-5066 | en_US |
dc.authorid | 0000-0001-6548-7823 | en_US |
dc.authorid | 0000-0003-4163-9962 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.wos | WOS:000921392400001 | |
dc.identifier.wos | WOS:000921392400001 | en_US |
dc.identifier.scopus | 2-s2.0-85144454542 | en_US |
dc.institutionauthor | Tanaman, Irmak | |
dc.institutionauthor | Karahan, Selim | |
dc.institutionauthor | Şahin, Hasan | |
dc.institutionauthor | Boğa, Mehmet | |
dc.identifier.doi | 10.1016/j.sajb.2022.12.020 | en_US |
dc.identifier.scopusquality | Q2 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |