Editorial: Acute leukemias: molecular characterization, leukemia-initiating cells, and influence of the microenvironment

Abstract

Acute leukemias remain a challenge, in spite of improvements in diagnosis and treatment. Fully establishing the depth and extent of the relative impact of the molecular mechanisms of disease progression and the pathways to recurrent disease will require decades of research, until our comprehension enables the routine development of simple and effective cures. This special issue was aimed to address progress in the characterization of the molecular basis of acute leukemias and to explore potential links with disease course.