Evaluation of the effect of EDTA on root coverage at free gingival graft procedure

Abstract

Aim: The present study was designed to compare the effect of root surface biomodification with ethylenediaminetetraacetic acid (EDTA) for the treatment of buccal gingival recession using the free gingival graft (FGG) technique.Methodology: In this randomized controlled parallel clinical trial, 34 patients with 40 teeth with Miller Class I and Class II gingival recessions were treated using FGG. The 40 teeth with recessions were assigned randomly to receive FGG with or without the application of EDTA gel. On pre-treatment (Day 0) and at 3-months and 6-months post-treatment, the following parameters were measured: gingival recession height (GRH), gingival recession width (GRW), probing pocket depth (PD), clinical attachment level (CAL), and width of keratinized tissue (WKT).Results: In the FGG+EDTA group, statistically significant changes from baseline were found: GRH decreased from 4.71.5 mm to 1.31.2 and WKT increased from 0.90.9 mm to 5.51.8 mm. In the FGG group, GRH decreased from 4.61.3 mm to 1.31.2 mm and WKT increased from 0.90.7 mm to 5.41.5 mm. For the FGG and FGG+EDTA groups, averagerootcoveragewasfoundtobe74.14%and69.26%, respectively.Conclusions: Thedatademonstratedthattherootsurface biomodification agent, EDTA, had no beneficial effect on root coverage.