Browsing Eczacılık Fakültesi Temel Eczacılık Bilimleri Bölümü Koleksiyonu by Issue Date
Now showing items 1-20 of 85
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Potential hepatoprotective effect of matricaria pubescens on high-fat diet-induced non-alcoholic fatty liver disease in rats
(Wiley, 16.03.2024)This study aimed to identify the phytochemical compounds of Matricaria pubescens by LC–MS/MS and evaluate the potential protective effect of its supplementation in high-fat diet (HFD)-induced non-alcoholic fatty liver ... -
Alchemilla pseudocartalinica Juz: Phytochemical screening by UPLC-MS/MS, molecular docking, anti-oxidant, anti-diabetic, anti-glaucoma, and anti-alzheimer effects
(ACG Publications, 18.03.2024)Alchemilla species (Rosaceae) are popularly known as 'Lady's Mantle, Lion's claw' and are used for medicinal purposes as diuretic, laxative, tonic, and wound healing agents. Bioactivities and phenolic content of Alchemilla ... -
Chemical constituents, cytotoxic, antioxidant and cholinesterases inhibitory activities of Silene Compacta (fischer) extracts
(Marmara University, 2017)In Turkey, Silene species have been used as infusion in urinary bladder and biliary tract diseases in traditional medicine. Silene species have been also consumed as food in Anatolia and Europe. In this study, the phenolic, ... -
Simultaneous quantification of phenolic acids and flavonoids in Chamaerops humilis L. using LC-ESI-MS/MS
(Sociedade Brasileira de Ciencia e Tecnologia de Alimentos, SBCTA, 2018)In this study, heated reflux extraction method has been used to identify the phenolic compounds from C. humilis var. argentea leaflets, rachis and fruits. Extractions were performed in both ultrapure water and 80% methanol ... -
An LC-MS/MS method validation for the phytochemical quantification of four edible plants
(Iğdır Üniversitesi Fen Bilimleri Enstitüsü, 2018)A comprehensive LC-MS/MS method was developed and validated for the quantification of eight plant phytochemicals (cynarin, caffeic acid, syringic acid, p-coumaric acid, o-coumaric acid, vanillic acid, ferulic acid, chlorogenic ... -
Tunceli Dağ Sarımsağının ( Allium tuncelianum ) rat kalp dokusu antioksidan enzim düzeylerine etkisi ve fenolik bileşenlerinin karakterizasyonu
(Kahramanmaraş Sütçü İmam Üniversitesi, 2018)Bu çalışmada, Allium tuncelianum'un su ekstraktlarının, fenolikbileşikleri LC-MS/MS ve HPLC ile belirlenmiştir. Antioksidan enzimdüzeylerine etkisini belirlemek için Wistar albino tipi dişi sıçanlarkullanılmıştır. Her ... -
Antioxidant, acetylcholinesterase and butyrylcholinesterase inhibition profiles of histamine schiff bases
(Turkish Chemical Society, 2019)In this work, a series of histamine Schiff bases H(1-20) were assayed for antioxidant properties by using different bioanalytical methods such as DPPH-free radical scavenging assay, ABTS cation radical decolarization, ... -
Comprehensive analysis of an uninvestigated wild edible medicinal garlic species from Turkey: Allium macrochaetum Boiss. & Hausskn.
(Blackwell Publishing Ltd., 2019)The study was aimed to investigate the phenolic compounds of Allium macrochaetum by LC-MS/MS, as well as the antioxidant, antialzheimer, and antimicrobial activities of the extracts, and determination of the essential oil ... -
Quantitation of fat soluble vitamins in different walnut genotypes and commercial cultivars; a comprehensive and robust LC-MS/MS method validation
(Iğdır Üniversitesi Fen Bilimleri Enstitüsü, 2019)Walnut, being both nutritious and delicious, has been regarded as a health food due to its preventive and therapeutic effects. In the present study, a robust LC-MS/MS analytical method was developed to simultaneously ... -
Design, synthesis and biological evaluation of 1,3-diaryltriazene-substituted sulfonamides as antioxidant, acetylcholinesterase and butyrylcholinesterase inhibitors
(Turkish Chemical Society, 2019)1,3-diaryltriazenes are one of the most useful and important linkers for many pharmaceutical applications. Therefore, in the current work, a series of 1,3-diaryltriazene sulfonamides 4(a-k) were synthesized by reacting ... -
Trace element analysis in some plants species by inductively coupled plasma optical emission spectrometry (ICP-OES)
(Iğdır Üniversitesi Fen Bilimleri Enstitüsü, 2019)In this study, the whole parts of eight edible and medicinal species (Alcea rosea, Carduuspycnocephalus subsp. albidus, Euphorbia gaillardotii, Euphorbia macroclada, Hypericum triquetrifolium,Kickxia lanigera, Malvella ... -
Synthesis, characterization and biological evaluation of novel dihydropyranoindoles improving the anticancer effects of HDAC inhibitors
(MDPI AG, 2020)The dihydropyranoindole scaffold was identified as a promising target for improving the anti-cancer activity of HDAC inhibitors from the preliminary screening of a library of compounds. A suitable methodology has been ... -
The Hemetsberger reaction: A new approach to the synthesis of novel dihydroindoloindole systems
(Arkat Usa Inc, 2020)The Hemetsberger indole synthesis provides an alternative method for the preparation of dihydroindoloindole systems. Two novel examples, dimethyl 3,8-dihydroindolo[7,6-g]indole-2,7-dicarboxylate and dimethyl 1,6dihydroin ... -
Trace element analysis in some salvia species by inductively coupled plasma-mass spectrometry (Icp-ms) and chemometric approach
(Marmara University, 2020)In this study, the stems, leaves, flowers, roots and mixed all parts of five Salvia species were analyzed for their trace element (Li, Be, V, Cr, Co, Ni, Cu, Zn, As, Se, Rb, Sr, Ag, Cd, Cs, Ba, Hg, Tl, Pb, and U) contents ... -
A comparative bio-evaluation and chemical profiles of Calendula officinalis L. extracts prepared via different extraction techniques
(MDPI AG, 2020)Calendula officinalis L., (marigold), well known for its medicinal properties, has been extensively studied for its therapeutic properties. Nonetheless, as far as the literature could establish, no study has attempted to ... -
Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
(Taylor and Francis Ltd., 2020)A series of novel calix[4]azacrown substituted sulphonamide Schiff bases was synthesised by the reaction of calix[4]azacrown aldehydes with different substituted primary and secondary sulphonamides. The obtained novel ... -
Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile
(Taylor and Francis Ltd, 2020)A series of 16 novel benzenesulfonamides incorporating 1,3,5-triazine moieties substituted with aromatic amines, dimethylamine, morpholine and piperidine were investigated. These compounds were assayed for antioxidant ... -
Determination of antioxidant, cytotoxic, anticholinesterase, antiurease, antityrosinase, and antielastase activities and aroma, essential oil, fatty acid, phenolic, and terpenoid-phytosterol contents of Salvia poculata
(Elsevier B.V., 2020)In this study, the essential oil, aroma, fatty acid, terpeneoid and phenolic contents of Salvia poculata were investigated. Additionally, antioxidant, toxic-cytotoxic activities of essential oil and the ethanol extracts ... -
Cannabinoids for SARS-CoV-2 and is there evidence of their therapeutic efficacy?
(Tubitak Scientific & Technical Research Council, 2021)Abstract: To combat the coronaviruses and their novel variants, therapeutic drugs and the development of vaccines that are to be effective throughout human life are urgently needed. The endocannabinoid system (ECS) acts ... -
Synthesis, characterization and biological evaluation of esterderivatives of 4-(diethylamino) salicylaldehyde cholinesterase and tyrosinase inhibitors
(INESEG Yayıncılık, 2021)Alzheimer's disease, one of the diseases that still has no a specific therapy, has become amajor public health issue owing to the increasing population of the elderly, particularly in richcountries. Inhibitory of cholinesterase ...
